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CAS No.: 1464151-33-4
Synonyms: ETC-1907206
ETC-206 is a selective MNK1 and MNK2 inhibitor with IC50s of 64 nM and 86 nM, respectively.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT03414450 | Ph+ Acute Lymphoblastic Leukem... more >>ia (Ph+ALL) Ph- Acute Lymphoblastic Leukemia (Ph-ALL) Chronic Myeloid Leukemia Accelerated Phase (CML-AP, Ph+) Chronic Myeloid Leukemia Blast Crisis (CML-BC, Ph+) Collapse << | Phase 1 | Withdrawn(Withdrawal requested... more >> by D3) Collapse << | February 2023 | United States, Georgia ... more >> Winship Cancer Institute, Emory University Atlanta, Georgia, United States, 30322 United States, Maryland The Center for Cancer and Blood Disorders Bethesda, Maryland, United States, 20874 United States, New York Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 United States, Oregon Oregon Health & Science University Portland, Oregon, United States, 97239 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Singapore Singapore General Hospital Singapore, Singapore, 169608 Collapse << |
实验方案
技术信息
CAS号 | 1464151-33-4 | 储存条件 |
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分子式 | C25H20N4O2 | 运输 | 蓝冰 | |||||||
分子量 | 408.45 | 别名 | ETC-1907206 | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT03414450 | Ph+ Acute Lymphoblastic Leukem... more >>ia (Ph+ALL) Ph- Acute Lymphoblastic Leukemia (Ph-ALL) Chronic Myeloid Leukemia Accelerated Phase (CML-AP, Ph+) Chronic Myeloid Leukemia Blast Crisis (CML-BC, Ph+) Collapse << | Phase 1 | Withdrawn(Withdrawal requested... more >> by D3) Collapse << | February 2023 | United States, Georgia ... more >> Winship Cancer Institute, Emory University Atlanta, Georgia, United States, 30322 United States, Maryland The Center for Cancer and Blood Disorders Bethesda, Maryland, United States, 20874 United States, New York Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 United States, Oregon Oregon Health & Science University Portland, Oregon, United States, 97239 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Singapore Singapore General Hospital Singapore, Singapore, 169608 Collapse << |
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