CAS No.: 1439901-97-9
Tirabrutinib HCl Catalog No. CSN17862
Synonyms: ONO-4059 hydrochloride;GS-4059 hydrochloride;ONO-4059 (hydrochloride)
ONO-4059 is a selective inhibitor of BTK with IC50 2.2 nm, ONO-4059 binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Walter HS, Rule SA, et al. A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies. Blood. 2016 Jan 28;127(4):411-9.
- [2] Akinleye A, Chen Y, et al. Ibrutinib and novel BTK inhibitors in clinical development. J Hematol Oncol. 2013 Aug 19;6:59.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1439901-97-9 | 储存条件 |
|
|
| 分子式 | C25H23ClN6O3 | 运输 | 蓝冰 | |
| 分子量 | 490.94 | 别名 | ONO-4059 hydrochloride;GS-4059 hydrochloride;ONO-4059 (hydrochloride);GS-4059;ONO-WG-307;ONO-4059 HCl;ONO-4059;Tirabrutinib |
