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CAS No.: 238750-77-1
Synonyms: CHR-2797
Tosedostat is a aminopeptidase inhibitor with IC50 of 220, > 1000 nM for aminopeptidase N and aminopeptidase B respectively.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01638442 | Healthy | Phase 1 | Unknown | September 2012 | United States, Indiana ... more >> Covance Clinical Research Unit Inc. Evansville, Indiana, United States, 47710 Collapse << |
NCT00692354 | Advanced Solid Tumors | Phase 1 | Completed | - | - |
NCT01636609 | Acute Myeloid Leukemia ... more >> High Risk Myelodysplastic Syndrome Collapse << | Phase 1 Phase 2 | Active, not recruiting | November 30, 2018 | United States, Texas ... more >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
实验方案
技术信息
CAS号 | 238750-77-1 | 储存条件 |
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分子式 | C21H30N2O6 | 运输 | 蓝冰 | |||||||
分子量 | 406.47 | 别名 | CHR-2797 | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01638442 | Healthy | Phase 1 | Unknown | September 2012 | United States, Indiana ... more >> Covance Clinical Research Unit Inc. Evansville, Indiana, United States, 47710 Collapse << |
NCT00692354 | Advanced Solid Tumors | Phase 1 | Completed | - | - |
NCT01636609 | Acute Myeloid Leukemia ... more >> High Risk Myelodysplastic Syndrome Collapse << | Phase 1 Phase 2 | Active, not recruiting | November 30, 2018 | United States, Texas ... more >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT01567059 | Acute Myeloid Leukemia With Mu... more >>ltilineage Dysplasia Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities Adult Acute Myeloid Leukemia With Del(5q) Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) de Novo Myelodysplastic Syndromes Previously Treated Myelodysplastic Syndromes Secondary Acute Myeloid Leukemia Secondary Myelodysplastic Syndromes Untreated Adult Acute Myeloid Leukemia Collapse << | Phase 2 | Completed | - | United States, Washington ... more >> Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium Seattle, Washington, United States, 98109 Collapse << |
NCT00522938 | Carcinoma, Non-Small-Cell Lung | Phase 1 Phase 2 | Terminated(Very poor recruitme... more >>nt of patients to the study) Collapse << | - | United States, California ... more >> Tower Cancer Research Foundation Beverly Hills, California, United States, 90210 Medical Oncology Care Associates Orange, California, United States, 92868 United States, Kentucky Oncology Associates of West Kentucky Paducah, Kentucky, United States, 42003 United States, New York Montefiore Medical Center Bronx, New York, United States, 10467 Richmond University Medical Center Staten Island, New York, United States, 10310 United States, North Carolina Clinworks Research Center Charlotte, North Carolina, United States, 28207 Carolina BioOncology Institute Huntersville, North Carolina, United States, 28070 Collapse << |
NCT00737555 | Solid Tumor | Phase 1 | Completed | - | Netherlands ... more >> UMC St Radboud Nijmegen, Netherlands, 6525 GA Erasmus MC University Medical Centre- Location Centrum Rotterdam, Netherlands, 3015 CE Collapse << |
NCT02352831 | Pancreatic Cancer ... more >> Cancer of Pancreas Cancer of the Pancreas Pancreas Cancer Collapse << | Phase 1 Phase 2 | Terminated(Insufficient fundin... more >>g and drug supply from manufacturer) Collapse << | - | United States, Missouri ... more >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 Collapse << |
NCT01180426 | Acute Myeloid Leukemia | Phase 2 | Unknown | June 2013 | United States, California ... more >> UCLA Division of Hematology/Oncology Los Angeles, California, United States, 90095 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109-2800 United States, New Jersey John Theurer Cancer Center Hackensack, New Jersey, United States, 07601 United States, New York New York Presbyterian Hospitacl New York, New York, United States, 10021 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Texas MD Anderson Houston, Texas, United States, 77030-4009 Collapse << |
NCT02452346 | Myelodysplastic Syndrome | Phase 2 | Completed | - | United States, New York ... more >> Weill Cornell Medical College New York, New York, United States, 10065 Collapse << |
NCT00689000 | Acute Myeloid Leukemia ... more >> Myelodysplastic Syndrome Multiple Myeloma Collapse << | Phase 1 Phase 2 | Completed | - | United Kingdom ... more >> Nexus Oncology Ltd Edinburgh, Scotland, United Kingdom, EH25 9PP Collapse << |
NCT00780598 | Acute Myeloid Leukemia ... more >> AML Collapse << | Phase 2 | Completed | - | - |
NCT02452346 | - | - | Completed | - | - |
NCT02352831 | - | - | Terminated(Insufficient fundin... more >>g and drug supply from manufacturer) Collapse << | - | - |
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