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CAS No.: 1493764-08-1
Synonyms: UNC2881
UNC2881 is a Mer kinase inhibitor and can inhibit the phosphorylation of Mer with IC50 of 4.3 nM.
生物活性
实验方案
技术信息
CAS号 | 1493764-08-1 | 储存条件 |
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分子式 | C25H33N7O2 | 运输 | 蓝冰 | |||||
分子量 | 463.58 | 别名 | UNC2881 | |||||
溶解度 |
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动物实验配方 |
Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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697 B-ALL cells | - | Function assay | 1 h | Inhibition of Mer kinase phosphorylation in human 697 B-ALL cells after 1 hr by Western blot analysis, IC50=0.022 μM | 24219778 |
mouse 32D-EMC cells | - | Function assay | - | Inhibition of EGF-induced human intracellular domain of Mer/extracellular domain of EGFR phosphorylation expressed in mouse 32D-EMC cells after 1 hr by Western blot analysis | 24219778 |
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