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The formyl peptide receptors (FPR) belong to a class of G protein-coupled receptors involved in chemotaxis. In humans, there are three formyl peptide receptor isoforms, each encoded by a separate gene that are named FPR1, FPR2, and FPR3.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN25759 | WRW4 | 878557-55-2 | WRW4 is a selective antagonist of formyl peptide receptor 2 (FPR2) signaling. It can inhibit WKYMVm binding to FPR2 with IC50 of 0.23 μM. |
| CSN26347 | WKYMVdM | 187986-17-0 | WKYMVM is a very potent agonist of formyl peptide receptor members FPR1/FPR2 (EC50 1 nM) and FPRL1/FPRL2 (75 pM and 3 nM, respectively). |
| CSN25764 | WKYMVM | 187986-11-4 | WKYMVM is a selective agonist for the formyl peptide receptors FPR2 and FPR3. |
| CSN25761 | FPR Agonist 43 | 903895-98-7 | TC-FPR 43 is a potent formyl peptide receptor 2 (FPR2) agonist with EC50 of 44 nM. |
| CSN25760 | PBP10 | 794466-43-6 | PBP 10 is a selective antagonist of formyl peptide receptor 2 (FPR2). It can selectively inhibit FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. |
| CSN25309 | HCH6-1 | 1435265-06-7 | HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1) and may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases. |
| CSN22896 | Cyclosporin H | 83602-39-5 | Cyclosporin H is a potent and effective inhibitor of formyl peptide receptor (FPR) with Ki of 0.1 uM. |
| CSN25758 | (6S,9S,12S)-12-Benzyl-9-isobutyl-2,2-dimethyl-6-(2-(methylthio)ethyl)-4,7,10-trioxo-3-oxa-5,8,11-triazatridecan-13-oic acid | 67247-12-5 | Boc-MLF is an antagonist of formyl peptide receptor 1 (FPR1). |
| CSN27284 | ACT-389949 | 1258417-54-7 | ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2). |
| CSN25763 | Quin C1 | 786706-21-6 | |
| CSN25762 | (2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S)-35-((S)-2-Amino-4-methylpentanamido)-11,26-dibenzyl-29-((S)-sec-butyl)-8,23-bis(3-guanidinopropyl)-20,32-bis(hydroxymethyl)-14,17-diisobutyl-5-isopropyl-2-(2-(methylthio)ethyl)-4,7,10,13,16,19,22,25,28,31,34-undecaoxo-3,6,9,12,15,18,21,24,27,30,33-undecaazaoctatriacontane-1,38-dioic acid | 271246-66-3 | |
| CSN25757 | N'-(4-(Benzyloxy)-3-methoxybenzylidene)benzo[d][1,3]dioxole-5-carbohydrazide | 329691-12-5 | |
| CSN36844 | BML-111 | 78606-80-1 |
