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The formyl peptide receptors (FPR) belong to a class of G protein-coupled receptors involved in chemotaxis. In humans, there are three formyl peptide receptor isoforms, each encoded by a separate gene that are named FPR1, FPR2, and FPR3.

FPR

货号 产品名 CAS号 信息
CSN25759 WRW4 878557-55-2 WRW4 is a selective antagonist of formyl peptide receptor 2 (FPR2) signaling. It can inhibit WKYMVm binding to FPR2 with IC50 of 0.23 μM.
CSN26347 WKYMVM 187986-17-0 WKYMVM is a very potent agonist of formyl peptide receptor members FPR1/FPR2 (EC50 1 nM) and FPRL1/FPRL2 (75 pM and 3 nM, respectively). 
CSN25764 WKYMVM 187986-11-4 WKYMVM is a selective agonist for the formyl peptide receptors FPR2 and FPR3.
CSN25761 FPR Agonist 43 903895-98-7 TC-FPR 43 is a potent formyl peptide receptor 2 (FPR2) agonist with EC50 of 44 nM.
CSN25760 PBP10 794466-43-6 PBP 10 is a selective antagonist of formyl peptide receptor 2 (FPR2). It can selectively inhibit FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils.
CSN25309 HCH6-1 1435265-06-7 HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1) and may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases.
CSN22896 Cyclosporin H 83602-39-5 Cyclosporin H is a potent and effective inhibitor of formyl peptide receptor (FPR) with Ki of 0.1 uM.
CSN25758 (6S,9S,12S)-12-Benzyl-9-isobutyl-2,2-dimethyl-6-(2-(methylthio)ethyl)-4,7,10-trioxo-3-oxa-5,8,11-triazatridecan-13-oic acid 67247-12-5 Boc-MLF is an antagonist of formyl peptide receptor 1 (FPR1).
CSN27284 ACT-389949 1258417-54-7 ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2).
CSN25763 Quin C1 786706-21-6
CSN25762 (2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S)-35-((S)-2-Amino-4-methylpentanamido)-11,26-dibenzyl-29-((S)-sec-butyl)-8,23-bis(3-guanidinopropyl)-20,32-bis(hydroxymethyl)-14,17-diisobutyl-5-isopropyl-2-(2-(methylthio)ethyl)-4,7,10,13,16,19,22,25,28,31,34-undecaoxo-3,6,9,12,15,18,21,24,27,30,33-undecaazaoctatriacontane-1,38-dioic acid 271246-66-3
CSN25757 N'-(4-(Benzyloxy)-3-methoxybenzylidene)benzo[d][1,3]dioxole-5-carbohydrazide 329691-12-5
CSN36844 BML-111 78606-80-1
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