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VEGFR

VEGFR

货号 产品名 CAS号 信息
CSN16336 XL647 781613-23-8 XL647 or tesevatinib inhibits EGFR, HER2, VEGFR and EphB4 with potential antineoplastic activity.
CSN25326 Tyrphostin AG1433 168835-90-3 Tyrphostin AG1433 is a tyrosine kinases inhibitor and also a selective PDGFRβ and VEGFR-2 (Flk-1/KDR) inhibitor with IC50s of 5.0 μM and 9.3 μM, respectively.
CSN20516 SU5408 15966-93-5 SU5408 is a VEGFR2 kinase inhibitor with IC50 of 70 nM in murine.
CSN21274 SU5208 62540-08-3 SU5208 is an analogue of SU5025.
CSN20604 Su5205 3476-86-6 Su5205 is an inhibitor of VEGFR2.
CSN17169 SKLB1002 1225451-84-2 SKLB1002 is a selective inhibitor of VEGFR2 with IC50 of 32 nM.
CSN17854 SAR131675 1433953-83-3 SAR131675 is selective inhibitor of VEGFR3 with IC50 and Ki of 23 nM, 12 nM, respectively.
CSN17331 Regorafenib Monohydrate 1019206-88-2 Regorafenib is a multi-target inhibitor. It can inhibit the activities of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 and their IC50 values ​​range from 1.5 nM to 46 nM.
CSN17192 Motesanib Diphosphate 857876-30-3 Motesanib diphosphate is ATP-competitive inhibitor of VEGFR1, VEGFR2 and VEGFR3 with IC50 of 2 nM, 3 nM and 6 nM, respectively. It also shows better inhibitory activity against c-Kit, PDGFR, and RET.
CSN26936 1-(4-((6-Amino-5-((methoxyimino)methyl)pyrimidin-4-yl)oxy)-2-chlorophenyl)-3-ethylurea 951151-97-6 JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively .
CSN17542 Fruquintinib 1194506-26-7 Fruquintinib is an inhibitor of VEGFR family with IC50s of 33 nM, 35 nM and 0.5 nM for VEGFR1, 2, 3 respectively.
CSN21898 Cediranib 288383-20-0 Cediranib is a multiple RTKs inhibitor with IC50 values of <0.001μM, 0.005μM, ≤0.003μM, 0.002μM and 0.005μM for VEGFR-2, VEGFR-1, VEGFR-3, c-Kit and PDGFR-β(measured kinase activity), respectively.
CSN16877 Cabozantinib Malate 1140909-48-3 Cabozantinib S-malate is a VEGFR2 inhibitor with IC50 of 0.035 nM. It also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM-11.3 nM.
CSN21290 SU5204 186611-11-0 Analogue of SU5025
CSN23266 4,4-Bis(4-aminophenoxy)biphenyl 13080-85-8 4,4'-Bis(4-aminophenoxy)biphenyl is a potent Flk-1 (VEGFR2) inhibitor.
CSN16990 2,4-Pyrimidinediamine with Linker 1430089-64-7 2,4-Pyrimidinediamine with linker is a multikinase inhibitor with a -NH2 terminal linker.
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