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VEGFR

VEGFR

货号 产品名 CAS号 信息
CSN20194 α-Cembrenediol 57605-80-8 VEGFR inhibitor TC1 acts in angiogenesis inhibitory in multiple breast cancer cell lines by significantly reducing the activated VEGFR2 levels.
CSN25326 Tyrphostin AG1433 168835-90-3 Tyrphostin AG1433 is a tyrosine kinases inhibitor and also a selective PDGFRβ and VEGFR-2 (Flk-1/KDR) inhibitor with IC50s of 5.0 μM and 9.3 μM, respectively.
CSN20516 SU5408 15966-93-5 SU5408 is a VEGFR2 kinase inhibitor with IC50 of 70 nM in murine.
CSN21274 SU5208 62540-08-3 SU5208 is an analogue of SU5025.
CSN20604 Su5205 3476-86-6 Su5205 is an inhibitor of VEGFR2.
CSN21922 SU1498 168835-82-3 SU1498 is a selective inhibitor of the VEGFR2 with IC50 of 700 nM.
CSN20550 SU 4312 5812-07-7 SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively), which is selective over EGFR and c-Src tyrosine kinases.
CSN18523 R1530 882531-87-5 R1530 is the multikinase inhibitor with potential antiangiogenesis and antineoplastic activities.
CSN23179 Vatalanib Succinate 212142-18-2 Potent VEGFR inhibitor; also aromatase inhibitor
CSN27706 NVP-ACC789   300842-64-2 NVP-ACC789 is a selective VEGFR inhibitor with IC50 values of 0.02μM, 0.18μM and 0.38μM for VEGFR2, VEGFR3 and VEGFR1, respectively, as well as with less potency to PDGFR-β with IC50 value of 1.4μM.
CSN27655 MAZ51 163655-37-6 MAZ51 is a selective inhibitor of VEGFR-3 (Flt-4) tyrosine kinase.
CSN33135 Lucitanib HCl 1058137-84-0 Lucitanib is a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs).
CSN27743 GW806742X   579515-63-2 GW806742X is an ATP mimetic MLKL inhibitor with Kd value of 9.3μM, and a VEGFR2 inhibitor with IC50 value of 2nM.
CSN26565 GW768505A free base 501693-25-0 GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2, with a pIC50 of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity[1]。
CSN27589 Donafenib 1130115-44-4 Donafenib, also known as CM-4307, is a multikinase inhibitor of Raf kinase and receptor tyrosine kinases with IC50 of 6 nM, 20 nM and 22 nM for Raf-1, B-Raf and VEGFR-3, respectively.
CSN26133 Decursin 5928-25-6 Decursin is a cumarin isolated from Radix peucedani that exhibits a number of physiological actions including anticancer, antibacterial, antinematodal and antioxidant. It inhibited proliferation and angiogenesis of endothelial cells to suppress diabetic retinopathy via VEGFR2.
CSN26201 Chloropyramine HCl 6170-42-9 Chloropyramine hydrochloride is a histamine receptor H1 antagonist which can also inhibit the biochemical function of VEGFR-3. Chloropyramine hydrochloride may be useful in the treatment of invasive breast cancer.
CSN21898 Cediranib 288383-20-0 Cediranib is a multiple RTKs inhibitor with IC50 values of <0.001μM, 0.005μM, ≤0.003μM, 0.002μM and 0.005μM for VEGFR-2, VEGFR-1, VEGFR-3, c-Kit and PDGFR-β(measured kinase activity), respectively.
CSN19151 BFH772 890128-81-1 BFH772 selectively targets VEGFR2 kinase with IC50 of 3 nM.
CSN26521 (Z)-SKI V 927429-51-4 and a Kd of 3.06 μM. (Z)-SKI V inhibits Aurora A with an IC50 of 1.34 μM. (Z)-SKI V, a benzofuran derivative, has extensive cytotoxic effects on cancer cell lines[1].
CSN21290 SU5204 186611-11-0 Analogue of SU5025
CSN23266 4,4-Bis(4-aminophenoxy)biphenyl 13080-85-8 4,4'-Bis(4-aminophenoxy)biphenyl is a potent Flk-1 (VEGFR2) inhibitor.
CSN25675 (E)-FeCP-oxindole 884338-18-5 (E)-FeCP-oxindole is a selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) with IC50 of 214 nM.
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