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Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function. TNIK has been shown to interact with KIAA0090, although the significance is unclear. TNIK has been shown to phosphorylate Gelsolin, a protein involved in F-actin depolymerisation thus inducing cytoskeletal changes.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN17458 | Pim1 AKK1-IN-1 | 1093222-27-5 | Pim1 AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively and also inhibits MPSK1 and TNIK. |
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