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Chloride Channel
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN12365 | Shikonin | 517-89-5 | Shikonin is an inhibitor of TMEM16A chloride channel with IC50 of 6.5 μM, it's a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc.. |
| CSN15941 | Selamectin | 220119-17-5 | Selamectin is an avermectin derivative prepared by hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of parasites, which selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission. |
| CSN11822 | R(+)-IAA-94 | 54197-31-8 | R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels. |
| CSN22216 | NS1652 | 1566-81-0 | NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells. |
| CSN21767 | NPPB | 107254-86-4 | NPPB can act as a blocker of the chloride channel with IC50 of 100 nM-100 µM and inhibitor of cyclooxygenase (IC50 = 8 µM). |
| CSN12665 | Niflumic Acid | 4394-00-7 | Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. |
| CSN19806 | IAA-94 | 53108-00-2 | IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of chloride channels that binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM. |
| CSN22401 | Fluxametamide | 928783-29-3 | Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls. |
| CSN25671 | Eact | 461000-66-8 | Eact is an activator of TMEM16A calcium-activated chloride channel (CaCC) with EC50 of 3 μM. It is also transient receptor potential vanilloid 1 (TRPV1) channel activator (EC50 = 11.6 μM). |
| CSN27709 | Chlorotoxin | 163515-35-3 | Chlorotoxin is a small 36 amino-acid peptide identified from the venom of the scorpion Leiurus quinquestriatus. It works as a selective blocker of small conductance chloride channels. |
