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Chloride Channel
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN27627 | T16Ainh-A01 | 552309-42-9 | T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC). |
| CSN12365 | Shikonin | 517-89-5 | Shikonin is an inhibitor of TMEM16A chloride channel with IC50 of 6.5 μM, it's a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc.. |
| CSN15941 | Selamectin | 220119-17-5 | Selamectin is an avermectin derivative prepared by hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of parasites, which selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission. |
| CSN11822 | R(+)-IAA-94 | 54197-31-8 | R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels. |
| CSN22216 | NS1652 | 1566-81-0 | NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells. |
| CSN21767 | NPPB | 107254-86-4 | NPPB can act as a blocker of the chloride channel with IC50 of 100 nM-100 µM and inhibitor of cyclooxygenase (IC50 = 8 µM). |
| CSN12665 | Niflumic Acid | 4394-00-7 | Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. |
| CSN19806 | IAA-94 | 53108-00-2 | IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of chloride channels that binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM. |
| CSN33111 | Endovion | 265646-85-3 | Endovion is a blocker of both VRAC and CaCC with IC50 value around 400nM for blocking swelling-activated anion currents in HEK293 cells. |
| CSN27709 | Chlorotoxin | 163515-35-3 | Chlorotoxin is a small 36 amino-acid peptide identified from the venom of the scorpion Leiurus quinquestriatus. It works as a selective blocker of small conductance chloride channels. |
| CSN25670 | Ani 9 | 356102-14-2 | Ani 9 is selective TMEM16A blocker with IC50 of 77 nM. |
