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Lignans

Lignans

货号 产品名 CAS号 信息
CSN14378 Yangambin 13060-14-5 Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role.
CSN14378 Yangambin 13060-14-5 Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role.
CSN19977 Tracheloside 33464-71-0 Tracheloside, a natural product isolated and purified from the herbs of Trachelospermum jasminoides (Lindl.) Lem., significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC50 value of 0.31 mg/mL, a level of inhibition comparable to that of tamoxifen (IC50 = 0.43 mg/mL).
CSN15455 threo-7-O-Methylguaiacylglycerol β-Coniferyl Ether 150333-85-0 threo-7-O-Methylguaiacylglycerol β-coniferyl ether is a natural product isolated and purified from plants.
CSN16633 Sesamin 607-80-7 Sesamin is a natural product derived from sesame seeds, acting as a potent serum lipid-lowering food component.
CSN14645 Schizandriside 71222-06-5 Schizandriside, a natural product isolated and purified from the leaves of Miconia rubiginosa with anti-inflammatory effect, shows significant cytotoxicity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines with inhibitory concentration (IC50) values of 3.26-8.89 uM, and has inhibitory activities against nitric oxide and prostaglandin E(2) production in IFN-γ- and lipopolysaccharide-stimulated RAW 264.7 cells.
CSN19434 Schizandrin 7432-28-2 Schizandrin is a natural product possessing antioxidant and anti-inflammatory activities.
CSN18373 Schisantherin E 64917-83-5 Schisantherin E is a natural compound isolated from the active fraction of the fruits of Schisandra sphenanthera Rehd.
CSN18769 Schizantherin B 58546-55-7 Schisantherin B is a natural product isolated and purified from the seeds of Schisandra chinensis (Turcz.) Baill. showing good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
CSN16630 Schisantherin A 58546-56-8 Schisantherin A is a natural product isolated and purified from the herbs of Chelidonium majus with anti-microbial, anti-oxidant and anti-inflammatory properties, and is a specific inhibitor of Rac1b.
CSN16432 Schisandrin B 61281-37-6 Schisandrin B is a naturally occuring anti-inflammatory and antioxidant agent which can inhibit ROS production in microglia.
CSN16433 Schisandrin A 61281-38-7 Schisandrin A is a naturally occuring agonist of the adiponectin receptor 2 with an IC50 value of 3.5 µM.
CSN14350 Savinin 493-95-8 Savinin, a natural product isolated and purified from the heartwood of Pterocarpus santalinus with antiinflammatory effect, can significantly inhibit tumor necrosis factor (TNF)-a production in lipopolysaccharide (LPS)-stimulated RAW264.7 cells, and T cell proliferation elicited by concanavalin (Con A), without displaying cytotoxicity, and also exhibits potent spermicidal activity and significant insecticidal activity.
CSN12281 Pinoresinol 487-36-5 Pinoresinol, a natural product isolated and purified from the bark of Eucommia ulmoides Oliver, may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.
CSN18371 Pinoresinol Diglucoside 63902-38-5 Pinoresinol diglucoside is one of the major lignans with various pharmacological activities which could be isolated from Duzhong and other plant species.
CSN15574 Phillyrin 487-41-2 Phillyrin is a naturally occuring AMPK activity enhancer, isolated and purified from the fruits of Forsythia suspensa.
CSN13651 Nortrachelogenin 34444-37-6 Nortrachelogenin, a natural product isolated and purified from the herbs of Trachelospermum jasminoides, shows effects on the central nervous system producing depression in rabbits and is an agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors (GFRs), thereby efficiently synergizing with TRAIL exposure.
CSN19937 Licarin B 51020-87-2 Licarin B is a naturally occuring neolignan isolated from seeds of Myristica fragrans.
CSN14356 Isotaxiresinol 26194-57-0 Isotaxiresinol, a natural product isolated and purified from the branch of Taxus wallichiana, may be useful for treatment of postmenopausal osteoporosis, especially for prevention of bone fracture induced by estrogen deficiency, and prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha.
CSN14364 Eudesmin 526-06-7 Eudesmin, a natural product isolated and purified from the dry leaves of Haplophyllum perforatum Kar.et Kir.
CSN15454 erythro-Guaiacylglycerol β-Dihydroconiferyl Ether 135820-77-8 erythro-Guaiacylglycerol β-dihydroconiferyl ether is a natural product isolated and purified from the herbs of Canadian maple syrup.
CSN20489 Enterolactone 78473-71-9 Enterolactone is a mammalian lignan formed by the action of intestinal bacteria from plant lignan precursors present in the diet and is potential anti-cancer effect.
CSN20490 Enterodiol 80226-00-2 Enterodiol is a mammalian lignan formed by the action of intestinal bacteria from plant lignan precursors present in the diet and is potential anti-cancer effect.
CSN15668 DL-Syringaresinol 1177-14-6 DL-Syringaresinol, a natural product isolated and purified from the herbs of Liriodendron tulipifera, shows inhibitory activity of Helicobacter pylori motility with the IC50 value is 50 mg/mL, potently inhibit the proliferation of human promyelocytic HL-60 cells through G1 arrest and induction of apoptosis, induces vasorelaxation by enhancing NO production in endothelial cells via two distinct mechanisms, phosphatidylinositol 3-kinase/Akt- and (PLC)/Ca2+/CaMKKβ -dependent eNOS phosphorylation and Ca(2+)-dependent eNOS dimerization, and protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism.
CSN14117 Dihydroguaiaretic Acid 66322-34-7 Dihydroguaiaretic acid, a natural product isolated and purified from the aerial parts of Saururus chinensis.
CSN14119 Dehydrodiconiferyl Alcohol 4263-87-0 Dehydrodiconiferyl alcohol, a natural product isolated and purified from the stems of Cucurbita moschata., shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts, and can modulate the differentiation of Th17 and Th1 cells and suppress experimental autoimmune encephalomyelitis, it may be a potential candidate as an agent for the control of Th17 and Th1-mediated inflammatory diseases.
CSN16468 Arctigenin 7770-78-7 Arctigenin is a naturally occuring agonist of adiponectin receptor 1 with IC50 value of 2.6μM.
CSN16579 Anwulignan 107534-93-0 Anwuligan, a natural product isolated and purified from the fruits of Schisandra chinensis, possesses therapeutic potentials against neurodegenerative diseases with oxidative stress and neuroinflammation.
CSN23625 4'-Demethylpodophyllotoxin 40505-27-9 4'-Demethylpodophyllotoxin shows potent cytotoxic potential in diverse cancer cell lines, it's a lignan isolated from the herb of Dysosma pleiantha (Hance) Woodson.
CSN19973 (-)-Syringaresnol-4-O-β-D-Apiofuranosyl-(1→2)-β-D-Glucopyranoside 136997-64-3 (-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside is a natural product isolated and purified from Albizia julibrissin Duraz..
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