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AChE

AChE

货号 产品名 CAS号 信息
CSN12024 Tacrine HCl 1684-40-8 Tacrine HCl is a parasympathomimetic reversible cholinesterase inhibitor.
CSN11851 Rivastigmine 123441-03-2 Rivastigmine is a acetylcholinesterase inhibitor with IC50 value of 5.5 μM for cholinesterase, used for the treatment of mild to moderate Alzheimer's disease and Parkinson's disease.
CSN11807 Pyridostigmine Bromide 101-26-8 Pyridostigmine Bromide is a reversible cholinesterase inhibitor to treat myasthenia gravis.
CSN14156 Pseudopalmatine 19716-66-6 Pseudocolumbamine is a natural product isolated and purified from the herbs of Tinospora sinensis with antiplasmodial activity ,it's also a AChE inhibitor with IC50 of 1.8 μM.
CSN17059 Pralidoxime Chloride 51-15-0 Pralidoxime chloride is an AChE reactivator, used as an antidote to organophosphate pesticides and chemicals.
CSN24045 PItofenone HCl 1248-42-6 Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.
CSN20476 Pitofenone 54063-52-4 Pitofenone an AChE inhibitor with Ki values of 36 and 45 μM for bovine erythrocyte and electric eel enzyme, which shows anti-spasmodic activity in combination with Fenpiverinium and Diclofenac.
CSN14039 N-p-trans-Coumaroyltyramine 36417-86-4 N-p-trans-Coumaroyltyramine, a natural product isolated and purified from the herbs of Exochorda racemosa, is an α-glucosidase inhibitor(Ki = 840 nM in yeast) and an AChE inhibitor (IC50 = 34.5 mg/mL/122 mM), exhibits potent inhibition of cell proliferation, platelet aggregation, and shows antioxidant activity.
CSN16680 Itopride HCl 122892-31-3 Itopride HCl is a D2 antagonist and an AChE inhibitor with an IC50 value of 2.04±0.27 μM. It is a prokinetic benzamide derivative unlike domperidone.
CSN19291 Huperzine A 102518-79-6 Huperzine A is a naturally occurring sesquiterpene alkaloid AChE inhibitor.
CSN11139 Hederacoside C 14216-03-6 Hederacoside C is a naturally occuring saponin found in K. pictus with anti-inflammatory activity. It inhibited AChE with IC50 value of 31.3 μM.
CSN19397 Galanthamine 357-70-0 Galanthamine is a long-acting, centrally active acetylcholinesterase (AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors.
CSN12443 Galanthaminone 510-77-0 Galantamine is a competitive and reversible cholinesterase (AChE) inhibitor and is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.
CSN10888 Edrophonium Chloride 116-38-1 Edrophonium chloride is a competitive AchE inhibitor which can prevent breakdown of the neurotransmitter acetylcholine.
CSN16651 Donepezil 120014-06-4 Donepezil is a centrally acting reversible AchE inhibitor with IC50 of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively, a medication used to treat Alzheimer's disease.
CSN23810 Demecarium Bromide 56-94-0 Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM[1]. Demecarium Bromide (BC-48) is used as a glaucoma agent[2].
CSN27305 Coumaran 496-16-2 Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran can be used as a biopesticide.
CSN10698 Corydaline 518-69-4 Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.
CSN10483 Bretylium Tosylate 61-75-6 Bretylium tosylate is an antiarrhythmic agent.
CSN14035 beta-Amyrone 638-97-1 beta-Amyrone, a natural product isolated and purified from the leaves of Cyclocarya paliums with snakevenom inactivating action, exhibits moderate anti-acetylcholinesterase (AChE) activity.
CSN14397 alpha-Viniferin 62218-13-7 alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.
CSN19809 Acotiamide 185106-16-5 Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.
CSN23387 Acotiamide HCl 185104-11-4 Acotiamide HCl is the 2HCl form of acotiamide which is an inhibitor of AChE. It also acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonism that is used for the treatment of functional dyspepsia.
CSN22581 Acotiamide HCl 3H2O 773092-05-0 Acotiamide HCl 3H2O is AchE inhibitor which can increased Ach concentrations and lead to an improvement of gastric emptying and gastrointestinal motility and eventually to a reduction of dyspepsia symptoms.
CSN19329 Isochlorogenic Acid B 14534-61-3 3,4-Dicaffeoylquinic Acid is a polyphenol with diverse biological activities, it inhibits acetylcholinesterase (ACE) and α-glucosidase in a concentration-dependent manner, shows cytotoxic to NCI-H23 lung adenocarcinoma cells, as well as increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA and increases survival in a mouse model of influenza A infection.
CSN16855 (±)-Huperzine A 120786-18-7 (±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs of Lycopodium serratum, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD).
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