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AChE

AChE

货号 产品名 CAS号 信息
CSN12179 Valethamate Bromide 90-22-2 Valethamate bromide is generally used as an anticholinergic agent.
CSN12024 Tacrine HCl 1684-40-8 Tacrine HCl is a parasympathomimetic reversible cholinesterase inhibitor.
CSN15659 Skimmianin 83-95-4 Skimmianin, a natural product isolated and purified from the herbs of Skimmia japonica, is an inhibitor against the Leishmania APRT enzyme and a strong acetylcholinesterase (AChE) inhibitor, and has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats.
CSN11851 Rivastigmine 123441-03-2 Rivastigmine is a acetylcholinesterase inhibitor with IC50 value of 5.5 μM for cholinesterase, used for the treatment of mild to moderate Alzheimer's disease and Parkinson's disease.
CSN11807 Pyridostigmine Bromide 101-26-8 Pyridostigmine Bromide is a reversible cholinesterase inhibitor to treat myasthenia gravis.
CSN14156 Pseudopalmatine 19716-66-6 Pseudocolumbamine is a natural product isolated and purified from the herbs of Tinospora sinensis with antiplasmodial activity ,it's also a AChE inhibitor with IC50 of 1.8 μM.
CSN17059 Pralidoxime Chloride 51-15-0 Pralidoxime chloride is an AChE reactivator, used as an antidote to organophosphate pesticides and chemicals.
CSN22325 (+)-Phenserine 116839-68-0 Posiphen is a selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.
CSN24045 PItofenone HCl 1248-42-6 Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.
CSN20476 Pitofenone 54063-52-4 Pitofenone an AChE inhibitor with Ki values of 36 and 45 μM for bovine erythrocyte and electric eel enzyme, which shows anti-spasmodic activity in combination with Fenpiverinium and Diclofenac.
CSN14039 N-p-trans-Coumaroyltyramine 36417-86-4 N-p-trans-Coumaroyltyramine, a natural product isolated and purified from the herbs of Exochorda racemosa, is an α-glucosidase inhibitor(Ki = 840 nM in yeast) and an AChE inhibitor (IC50 = 34.5 mg/mL/122 mM), exhibits potent inhibition of cell proliferation, platelet aggregation, and shows antioxidant activity.
CSN16680 Itopride HCl 122892-31-3 Itopride HCl is a D2 antagonist and an AChE inhibitor with an IC50 value of 2.04±0.27 μM. It is a prokinetic benzamide derivative unlike domperidone.
CSN19291 Huperzine A 102518-79-6 Huperzine A is a naturally occurring sesquiterpene alkaloid AChE inhibitor.
CSN11139 Hederacoside C 14216-03-6 Hederacoside C is a naturally occuring saponin found in K. pictus with anti-inflammatory activity. It inhibited AChE with IC50 value of 31.3 μM.
CSN14086 Garcinone C 76996-27-5 Garcinone C, a natural product isolated and purified from the fruits of Garcinia mangostana, is the most potent inhibitor of AChE, the most active compound against both of pathogenic (MIC =100 μg/mL) and non-pathogenic leptospira (MIC = 200 μg/mL), and exhibits either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines in vitro.
CSN19397 Galanthamine 357-70-0 Galanthamine is a long-acting, centrally active acetylcholinesterase (AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors.
CSN19398 Galanthamine Hydrobromide 1953-04-4 Galanthamine hydrobromide is a natural occuring AchE inhibitor with IC50 value of 410nM and allosteric potentiator at neuronal nAchRs, used for the treatment of cognitive decline in mild to moderate Alzheimer's disease and various other memory impairments.
CSN12443 Galanthaminone 510-77-0 Galantamine is a competitive and reversible cholinesterase (AChE) inhibitor and is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.
CSN10888 Edrophonium Chloride 116-38-1 Edrophonium chloride is a competitive AchE inhibitor which can prevent breakdown of the neurotransmitter acetylcholine.
CSN16651 Donepezil 120014-06-4 Donepezil is a centrally acting reversible AchE inhibitor with IC50 of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively, a medication used to treat Alzheimer's disease.
CSN21326 Dimetacrine 4757-55-5 Dimetacrine is a useful antidepressant which can be used for the treatment of various types of depression.
CSN23810 Demecarium Bromide 56-94-0 Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM[1]. Demecarium Bromide (BC-48) is used as a glaucoma agent[2].
CSN27305 Coumaran 496-16-2 Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran can be used as a biopesticide.
CSN10698 Corydaline 518-69-4 Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.
CSN10483 Bretylium Tosylate 61-75-6 Bretylium tosylate is an antiarrhythmic agent.
CSN14035 beta-Amyrone 638-97-1 beta-Amyrone, a natural product isolated and purified from the leaves of Cyclocarya paliums with snakevenom inactivating action, exhibits moderate anti-acetylcholinesterase (AChE) activity.
CSN14397 alpha-Viniferin 62218-13-7 alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.
CSN10233 Aldicarb Sulfone 1646-88-4 Aldicarb sulfone, a carbamate insecticide, is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.
CSN19809 Acotiamide 185106-16-5 Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.
CSN23387 Acotiamide HCl 185104-11-4 Acotiamide HCl is the 2HCl form of acotiamide which is an inhibitor of AChE. It also acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonism that is used for the treatment of functional dyspepsia.
CSN19329 Isochlorogenic Acid B 14534-61-3 3,4-Dicaffeoylquinic Acid is a polyphenol with diverse biological activities, it inhibits acetylcholinesterase (ACE) and α-glucosidase in a concentration-dependent manner, shows cytotoxic to NCI-H23 lung adenocarcinoma cells, as well as increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA and increases survival in a mouse model of influenza A infection.
CSN24966 1-Naphthyl acetate 830-81-9 1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages.
CSN16855 (±)-Huperzine A 120786-18-7 (±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs of Lycopodium serratum, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD).
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