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P2Y Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN27554 | Uridine 5′-diphosphoglucose disodium salt | 28053-08-9 | Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR. |
| CSN23371 | UDP disodium salt | 27821-45-0 | UDP disodium salt is an endogenous agonist of P2Y receptor which preferentially activates P2Y6. It exhibis antagonistic effect on the P2Y14 receptor. |
| CSN12090 | Ticlopidine | 55142-85-3 | Ticlopidine is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor. |
| CSN13719 | Ticlopidine HCl | 53885-35-1 | Ticlopidine HCl is an adenosine diphosphate (ADP) receptor inhibitor that against platelet aggregation with IC50 of ~2 μM. |
| CSN12826 | Ticagrelor | 274693-27-5 | Ticagrelor is a reversibly and oral active P2Y12 receptor antagonist with Ki of 2 nM, also inhibits CYP2C9 and midazolam 4-hydroxylation with IC50 of 10.5 μM and 8.2 μM respectively. |
| CSN12020 | Suramin Sodium | 129-46-4 | Suramin sodium salt is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 (IC50 = 4.9 μM), blocks G protein coupling to GPCRs, and non-selectively antagonizes P2 purinergic receptors(10-100 μM). |
| CSN17880 | Suramin | 145-63-1 | Suramin is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 (IC50 = 4.9 μM), blocks G protein coupling to GPCRs, and non-selectively antagonizes P2 purinergic receptors(10-100 μM). |
| CSN16171 | Prasugrel | 150322-43-3 | Prasugrel is a platelet inhibitor with IC50 value of 1.8 μM. |
| CSN12325 | Prasugren HCl | 389574-19-0 | Prasugrel HCl is a platelet inhibitor with IC50 value of 1.8 μM. |
| CSN13178 | N6-(4-Hydroxybenzyl)-adenosine | 110505-75-4 | N6-(4-Hydroxybenzyl)adenosine is an inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM). |
| CSN11479 | MRS 2578 | 711019-86-2 | MRS2578 is a potent and selective P2Y6 nucleotide receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors. |
| CSN10679 | Clopidogrel Bisulfate | 135046-48-9 | Clopidogrel is an inhibitor of platelet aggregation that is used to decrease the risk of myocardial infarction and stroke in patients known to have atherosclerosis. Clopidogrel has been linked to rare instances of idiosyncratic, clinically apparent acute liver injury. |
| CSN15727 | Clopidogrel | 113665-84-2 | Clopidogrel is a P2Y12 receptor blocker (IC50 = 100 nM). |
| CSN15854 | Clopidogrel Hydrogen Sulfate | 120202-66-6 | Clopidogrel Hydrogen Sulfate is the functional enantiomer of clopidogrel and a potent P2Y12 receptor antagonist. |
