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Rho
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN19504 | Zoledronic Acid | 118072-93-8 | Zoledronic acid, a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. |
| CSN18268 | Y16 | 429653-73-6 | Y16 is an inhibitor of G-protein–coupled Rho GEFs and works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions. |
| CSN17515 | Rhosin | 1173671-63-0 | Rhosin is a specific Rho inhibitor which binds to WT RhoA with an affinity ~0.4 μM Kd while does not interfere with the binding of Cdc42 or Rac1. |
| CSN17657 | Rhosin hydrochloride | 1281870-42-5 | Rhosin HCl is a specific Rho inhibitor which binds to WT RhoA with an affinity ~0.4 μM Kd while does not interfere with the binding of Cdc42 or Rac1. |
| CSN21341 | Rho-Kinase-IN-1 | 1035094-83-7 | Rho-Kinase-IN-1 is a rho kinase inhibitor extracted from US 20090325960 A1, compound 1.008. |
| CSN18189 | Narciclasine | 29477-83-6 | Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner. |
| CSN27587 | MLS000532223 | 16616-39-0 | MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 ranging from 16 μM to 120 μM. Small GTPases are key regulators of cellular activity . |
| CSN22071 | ML-098 | 878978-76-8 | ML-098 is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM |
| CSN19188 | K-Ras(G12C) inhibitor 9 | 1469337-91-4 | K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras (G12C). |
| CSN19689 | CCG-232601 | 1922099-21-5 | CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma. |
| CSN25251 | CCG-222740 | 1922098-69-8 | CCG-222740 is a Rho/MRTF pathway inhibitor. It decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin (α-SMA) expression. It also modulates inflammatory components of the pancreas in KC mice (LSL-KrasG12D/+; Pdx-1-Cre) stimulated with caerulein. |
| CSN15952 | CCG-1423 | 285986-88-1 | CCG-1423 inhibits RhoA/C-mediated gene transcription and the invasion of rho-overexpressing cell lines. |
