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Rho
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN19504 | Zoledronic Acid | 118072-93-8 | Zoledronic acid, a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. |
| CSN18189 | Narciclasine | 29477-83-6 | Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner. |
| CSN27587 | MLS000532223 | 16616-39-0 | MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 ranging from 16 μM to 120 μM. Small GTPases are key regulators of cellular activity . |
| CSN19189 | K-Ras(G12C) Inhibitor 6 | 2060530-16-5 | K-Ras(G12C) inhibitor 6 is an allosteric, and selective inhibitor of oncogenic K-Ras (G12C). |
| CSN25251 | CCG-222740 | 1922098-69-8 | CCG-222740 is a Rho/MRTF pathway inhibitor. It decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin (α-SMA) expression. It also modulates inflammatory components of the pancreas in KC mice (LSL-KrasG12D/+; Pdx-1-Cre) stimulated with caerulein. |
| CSN15952 | CCG-1423 | 285986-88-1 | CCG-1423 inhibits RhoA/C-mediated gene transcription and the invasion of rho-overexpressing cell lines. |