Myosin | Cytoskeleton| CSNpharm

Myosin

Myosin
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货号	产品名	CAS号	信息
CSN16232	Omecamtiv mecarbil	873697-71-3	Omecamtiv mecarbil is a selective sarcomere-directed cardiac myosin activator with an EC50 of 0.6 μM.
CSN20537	Mavacamten	1642288-47-8	MYK-461 is a myosin inhibitor potentially for the treatment of hypertrophic cardiomyopathy, and can reduce contractility by decreasing the adenosine triphosphatase activity of the cardiac myosin heavy chain.
CSN10498	BTS	1576-37-0	BTS is a potent and selective inhibitor of Ca2+-stimulated myosin S1 ATPase with IC50 value of ~5 µM.
CSN33171	Aficamten	2364554-48-1	Aficamten is a cardiac myosin allosteric inhibitor.
CSN17147	(-)-Blebbistatin	856925-71-8	(-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases and the active enantiomer of (+)-blebbistatin. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50 = 0.5-5 µM), while poorly inhibiting smooth muscle myosin (IC50 = 80 µM).