Rapidly Accelerated Fibrosarcoma | MAPK/ERK Pathway| CSNpharm

Raf

Raf
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货号	产品名	CAS号	信息
CSN12243	ZM336372	208260-29-1	ZM336372 is an inhibitor of c-Raf with IC50 of 70 nM.
CSN16663	NVP-BHG712	940310-85-0	NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition and also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
CSN12290	L-779450	303727-31-3	L-779450 is a potent, ATP-competitive Raf kinase inhibitor (IC50 =10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively.
CSN18123	GW5074	220904-83-6	GW5074 is an inhibitor of c-Raf1 kinase with IC50 of 9 nM.
CSN27589	Donafenib	1130115-44-4	Donafenib, also known as CM-4307, is a multikinase inhibitor of Raf kinase and receptor tyrosine kinases with IC50 of 6 nM, 20 nM and 22 nM for Raf-1, B-Raf and VEGFR-3, respectively.
CSN16200	B-Raf Inhibitor 1	1093100-40-3	B-Raf inhibitor 1 is an inhibitor of B-Raf with IC50s ranging from 0.31 μM to 2 nM in cells assay.
CSN15686	B-Raf Inhibitor 1 2HCl	1191385-19-9	B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 μM and 2 nM for A375 proliferation and A375 p-ERK respectively.
CSN27778	CID-25014542	220904-99-4