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Raf

Raf

货号 产品名 CAS号 信息
CSN12243 ZM336372 208260-29-1 ZM336372 is an inhibitor of c-Raf with IC50 of 70 nM.
CSN22915 XRK3F2 2375193-43-2 XRK3F2 is a p62-ZZ domain inhibitor which can blunt MM-induced Runx2 suppression and induce new bone formation and remodeling.
CSN15889 TAK-632 1228591-30-7 TAK-632 is a selective pan-RAF kinase inhibitor with IC50 values of 2.4/1.4 nM for BRAF V600E/c-RAF with > 60 fold selectivity over VEGFR.
CSN12366 Sorafenib Tosylate 475207-59-1 Sorafenib tosylate is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively. Sorafenib tosylate suppresses both wild-type and V599E mutant BRAF activity in vitro.
CSN10381 Sorafenib 284461-73-0 Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM in cell-free assays, respectively.
CSN16576 SB-590885 405554-55-4 SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.
CSN12290 L-779450 303727-31-3 L-779450 is a potent, ATP-competitive Raf kinase inhibitor (IC50 =10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively.
CSN18123 GW5074 220904-83-6 GW5074 is an inhibitor of c-Raf1 kinase with IC50 of 9 nM.
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