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SGLT

SGLT

货号 产品名 CAS号 信息
CSN22533 Velagliflozin 946525-65-1 Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.
CSN17552 Tofogliflozin (hydrate) 1201913-82-7 Tofogliflozin is a potent and highly specific sodium/glucose cotransporter 2(SGLT2) inhibitor with Ki values of 2.9, 14.9, and 6.4 nM for human, rat, and mouse SGLT2.
CSN16054 Tofogliflozin 903565-83-3 Tofogliflozin is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with Ki values of 2.9, 14.9, and 6.4 nM for human, rat, and mouse SGLT2.
CSN20626 TA-1887 1003005-29-5 TA-1887 is a highly potent and selective hSGLT2 inhibitor, with pronounced antihyperglycemic effects in high-fat diet-fed KK (HF-KK) mice.
CSN11698 Phlorizin 60-81-1 Phlorizin is an inhibitor of hSGLT1 (Ki=300 nM) and hSGLT2 (Ki= 39 nM). It can be found in a number of fruit trees.
CSN11697 Phloretin 60-82-2 Phloretin, a dihydrochalcone flavonoid, can inhibit the active transport of glucose into cells by SGLT1 and SGLT2. It is mainly found in fruit and roots of apple tree.
CSN15831 Ertugliflozin 1210344-57-2 PF-04971729 is a selective sodium-dependent glucose cotransporter (SGLT) inhibitor which selectively targets SGLT2.
CSN15683 Sotagliflozin 1018899-04-1 LX4211 is an inhibitor of SGLT2 and SGLT1 with antidiabetic activity.
CSN19739 LX2761 1610954-97-6 LX2761 is a locally acting SGLT1 inhibitor that is highly potent in vitro and delays intestinal glucose absorption in vivo to improve glycemic control. LX2761 was designed to remain in the intestine after oral delivery to inhibit SGLT1 locally without affecting the SGLT1/2 mechanism in the kidney.
CSN21112 Licogliflozin 1291094-73-9 Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor
CSN16003 α-L-Rhamnose monohydrate 6155-35-7 L-Rhamnose, a natural product isolated and purified from the flowers of Scphora japonica L., increases serum propionate after long-term supplementation, but lactulose does not raise serum acetate, has anticancer potential, they exert a significant suppressive effect on tumour growth, and exhibits potent excellent sodium-glucose transporter (SGLT1 and SGLT2) inhibition activity.
CSN16022 Ipragliflozin 761423-87-4 Ipragliflozin is a selective inhibitor of SGLT2 with IC50 of 14 nM for hSGLT2.
CSN22259 Ipragliflozin (L-Proline) 951382-34-6 Ipragliflozin (L-Proline) selectively inhibits SGLT2 with IC50 of 2.8 nM.
CSN20593 Henagliflozin 1623804-44-3 Henagliflozin is a sodium glucose co-tranporter 2 inhibitor, with the IC50 values against human SGLT2 and SGLT1 were 2.38 and 4324 nmol/L, respectively, and is used for treating patients with type 2diabetes mellitus.
CSN23815 Ertugliflozin L-pyroglutamic acid 1210344-83-4 Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2].
CSN13801 Empagliflozin 864070-44-0 Empagliflozin is a selective inhibitor of SGLT-2 with IC50 of 3.1 nM.
CSN13871 Dapagliflozin ((2S)-1,2-propanediol, hydrate) 960404-48-2 Dapagliflozin propanediol is an inhibitor of SGLT2 that is used for the treatment of of type 2 diabetes mellitus.
CSN12342 Dapagliflozin 461432-26-8 Dapagliflozin is a selective inhibitor of SGLT2 with EC50 of 1.1 nM which is used to treat type 2 diabetes mellitus.
CSN16237 Canagliflozin hemihydrate 928672-86-0 Canagliflozin selectively inhibits SGLT2 with IC50 of 2.2 nM.
CSN12954 Canagliflozin 842133-18-0 Canagliflozin is a novel C-glucoside with thiophene ring.
CSN17473 Bexagliflozin (EGT1442) 1118567-05-7 Bexagliflozin is an inhibitor of SGLT2 with IC50 value of 2 nM.
CSN51385 Enavogliflozin 1415472-28-4
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