Chemokine Receptor | GPCR/G Protein|Immunology/Inflammation| CSNpharm

CCR

CCR
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货号	产品名	CAS号	信息
CSN12197	Vicriviroc Maleate	599179-03-0	Vicriviroc maleate is a CCR5 antagonist with IC50 of 0.91 nM in clinical development for the treatment of HIV-1.
CSN22613	SB297006	58816-69-6	SB297006 is a selective antagonist of CCR3 with IC50 of 39 nM.
CSN18192	RS-102895	300815-41-2	RS102895 is a potent and specific CCR2 antagonist with binding IC50 of 360 nM, no significant inhibition on CCR1 (IC50 > 17 μM).
CSN13797	RS-102895 HCl	1173022-16-6	RS102895 HCl is a potent and specific CCR2 antagonist with binding IC50 of 360 nM, no significant inhibition on CCR1 (IC50 > 17 μM).
CSN12845	RS-504393	300816-15-3	RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively).
CSN17712	PF-4136309	1341224-83-6	PF-4136309 is a potent, Selective, and orally bioavailable CCR2 antagonist.
CSN17807	NSC 5844	140926-75-6	NSC 5844 is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.
CSN23233	DAPTA	106362-34-9	DAPTA is a potent and selective CCR5 antagonist.
CSN18114	BX471	217645-70-0	BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1) and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
CSN18182	BX471 HCl	288262-96-4	BX471 HCl is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1) and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.