CRTH2/GPR44/DP2/Prostaglandin D2 Receptor 2 | GPCR/G Protein|Immunology/Inflammation| CSNpharm

CRTH2

CRTH2
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货号	产品名	CAS号	信息
CSN24302	MK-7246	1218918-62-7	MK-7246 is a potent and selective CRTH2 antagonist with Ki value of 2.5nM.
CSN20221	MK-2305	2101206-49-7	MK-2305 is a GPR40 partial agonist lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production.
CSN18830	Fevipiprant	872365-14-5	Fevipiprant is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood.
CSN22382	CRTh2 antagonist 1	1379445-54-1	CRTh2 antagonist 1是 CRTh2 的拮抗剂，IC50 值为89 nM。
CSN26623	CAY10471 Racemate	844639-57-2	CAY 10471 is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors with Ki values of 0.6, 1200, and >10,000 nM. Cat#531655 is a racemic mixture of CAY10471.
CSN16482	AZD1981	802904-66-1	AZD1981 is a potent and selective CRTh2 antagonist and displaces radio-labelled PGD2 from human recombinant DP2 with high potency (pIC50 = 8.4).
CSN22681	Vidupiprant	1169483-24-2	AMG 853 is a potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist (IC50 values are 8 and 35 nM, respectively in plasma).
CSN25231	AM211	1175526-27-8	AM211 is a potent and selective prostaglandin D2 receptor type 2 antagonist with IC50 value of 4.9nM.