欢迎来到 CSNpharm! 产品仅用于科研!
首页 Compound Arrays 促销产品
400-920-2911 sales@csnpharm.cn    

Dopamine Receptor

Dopamine Receptor

货号 产品名 CAS号 信息
CSN20169 Zicronapine 170381-16-5 Zicronapine is an atypical antipsychotic medication. Zicronapine exhibits monoaminergic activity and has a multi-receptorial profile. In vitro and in vivo it has shown potent antagonistic effects at dopamine D1, D2 and serotonin 5HT2A receptors.
CSN21891 Veralipride 66644-81-3 Veralipride is an antagonist of D2 receptor. It is used for the treatment of menopausal symptoms.
CSN23250 Trimethobenzamide HCl 554-92-7 Trimethobenzamide HCl is a dopamine D2 receptor antagonist and antiemetic drug.
CSN12086 Tiamenidine 31428-61-2 Thioridazine is an antipsychotic drug, used in the treatment of schizophrenia and psychosis, shows D4 selectivity or serotonin antagonism.
CSN22118 Sultopride HCl 23694-17-9 Sultopride HCl is a selective antagonist of dopamine D2 receptor
CSN27219 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol 99295-33-7 SKF-83566 is a potent, blood-brain permeable and orally active dopamine D1/D5 receptor antagonist . SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM and attenuates cocaine effects in vivo .
CSN18415 SKF-82958 Hydrobromide 74115-01-8 SKF-82958 hydrobromide is a D1/D5 receptor full agonist.
CSN20415 SKF 83959 Hydrobromide 67287-95-0 SKF 83959 hydrobromide is a dopamine D1-like receptor partial agonist (Ki values are 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively). It may act as an antagonist in vivo, producing anti-Parkinsonian effects and antagonizing the behavioral effects of cocaine.
CSN23554 SCH 23390 HCl 125941-87-9 SCH 23390 HCl is an antagonist of dopamine receptor D1 and D5 with Ki of 0.2 nM and 0.3 nM, respectively.
CSN23655 Ro 10-5824 2HCl 189744-94-3 Ro 10-5824 2HCl is an agonist of dopamine D4 receptor with Ki of 5.2 nM.
CSN25233 Raclopride 84225-95-6 Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively .
CSN21076 SCH23390 87134-87-0 Potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively). Blocks quinpirole-induced Kir3 (GIRK) currents (EC50 = 268 nM) independently of receptors.
CSN23271 PD 168077 Maleate 630117-19-0 PD 168077 maleate is an agonist of D4 dopamine receptor with Ki of 8.7 nM. It can induce synaptic translocation of CaMK II to postsynaptic sites in cultured prefrontal cortical neurons.
CSN18173 Pardoprunox HCl 269718-83-4 Pardoprunox HCl is a partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.
CSN27393 Paliperidone palmitate 199739-10-1 Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone. Paliperidone is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class. Paliperidone palmitate shows efficacy against schizophrenia.
CSN17271 MPTP HCl 23007-85-4 MPTP HCl is a neurotoxin that causes symptoms similar to parkinson's disease by destroying dopamine-producing nerve cells in the substantia nigra. It is widely used in the study of various animal models of Parkinson's disease.
CSN26125 ML417 1386162-69-1 ML417 is a novel and highly selective D3 dopamine receptor agonist with EC50 value of 38nM.
CSN19492 Metoclopramide HCl H2O 54143-57-6 Metoclopramide HCl is an antagonist of dopamine D2 receptor that is structurally related to procainamide. It has antiemetic and gastroprokinetic activities.
CSN23832 Mesoridazine Besylate 32672-69-8 Mesoridazine besylate is a phenothiazine dopamine receptor anatagonist. Mesoridazine besylate is described to demonstrate inhibition for D2DR and D4DR. It has a high affinity for dopamine D4 receptor. Mesoridazine besylate is an antipsychotic agent.
CSN23381 Melitracen HCl 10563-70-9 Melitracen HCl, a member of anthracenes, is an antagonist of dopamine D1 and D2 receptors. It is used as an antidepressant.
CSN21902 Lurasidone 367514-87-2 Lurasidone functions as an antagonist of the dopamine D2 and D3 receptors, the serotonin 5-HT2A and 5-HT7 receptors, the α2C-adrenergic receptor, and as a partial agonist of the serotonin 5-HT1A receptor.
CSN25316 L-745870 158985-00-3 L-745870 is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM and excellent brain penetration.
CSN19476 Haloperidol 52-86-8 Haloperidol is an antagonist of dopamine D2-like receptors (D1-D5) and it is used as a typical antipsychotic.
CSN27239 Fluphenazine 69-23-8 Fluphenazine is a typical antipsychotic used for symptomatic management of psychosis in patients with schizophrenia.
CSN17422 Dexpramipexole 2HCl 104632-27-1 Dexpramipexole 2HCl is the HCl form of Dexpramipexole which is a non-ergoline dopamine agonist for treatment of parkinson's disease and restless leg syndrome.Dexpramipexole is an (R)-(+) optical enantiomer of pramipexole.
CSN18775 Chlorprothixene 113-59-7 Chlorprothixene is an antagonist of multiple receptors including 5-HT2 (Ki = 3.4 nM), D1 (Ki = 18 nM), D2 (Ki = 18 nM), D3 (Ki = 4.56 nM), H1 (Ki = 3.75 nM), muscarinic acetylcholine receptors, α1-Adrenergic.
CSN20529 BP897 314776-92-6 BP897 is a partially selective dopamine D3 receptor agonist (Ki = 0.92 nM) that developed for the study of cocaine addiction.
CSN18441 Amisulpride HCl 81342-13-4 Amisulpride HCl is an antipsychotic drug, which is a selective dopamine antagonist (Ki=2.8 nM D2 receptor; Ki=3.2 nM D3 receptor).
CSN25294 ABT-724 70006-24-5 ABT-724 is a potent and highly selective dopamine D4 receptor agonist with EC50s of 12.4 nM, 14.3 nM and 23.2 nM for human dopamine D4 receptor, rat D4 receptor and ferret D4 receptor.
CSN25293 ABT-724 3HCl   587870-77-7 ABT-724 3HCl is a potent and highly selective dopamine D4 receptor agonist with EC50s of 12.4 nM, 14.3 nM and 23.2 nM for human dopamine D4 receptor, rat D4 receptor and ferret D4 receptor.
CSN22612 (+)-PD 128907 HCl 300576-59-4 (+)-PD 128,907 HCl is an agonist of D3 dopamine receptor with Ki of 2.3 nM.
CSN22323 (+)-Dihydrexidine HCl 158704-02-0 (+)-Dihydrexidine HCl is a dopamine D1 receptor agonist with an EC50 of 72± 21 nM.
CSN25685 (+)-AJ 76 HCl 85378-82-1 (+)-AJ 76 hydrochloride is an antagonist of dopamine receptor with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3, D4, hD2S, hD2L and rD2 receptors respectively).
<< PREV 1 2 3 4 5 NEXT >>