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货号 产品名 CAS号 信息
CSN25739 ZK 164015 177583-70-9 ZK 164015 is an antagonist of estrogen receptor. It inhibits 17β-estradiol stimulation of luciferase activity with IC50 of 0.025 μM.
CSN17566 Protirelin Acetate 120876-23-5 Protirelin is used to test the response of the anterior pituitary gland.
CSN28481 PROTAC ERRα Degrader-2 2306388-85-0 PROTAC ERRα Degrader-2 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-2 is an estrogen-related receptor alpha (ERRa) degrader.
CSN28500 PROTAC ERRα Degrader-1 2306388-84-9 PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an PROTAC estrogen-related receptor alpha (ERRa) degrader.
CSN26190 Propyl pyrazole triol 263717-53-9 Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%). PPT also exerts anti-diabetic effects in mouse models.
CSN21337 Nitromifene 10448-84-7 Nitromifene is an antagonist of estrogen receptor (ER).
CSN33124 Lasofoxifene 180916-16-9 Lasofoxifene is a non-steroidal selective estrogen receptor modulator (SERM).
CSN33125 Lasofoxifene HCl 180915-85-9 Lasofoxifene hydrochloride is a non-steroidal selective estrogen receptor modulator (SERM).
CSN19318 L-Thyroxine Sodium Pentahydrate 6106-07-6 L-Thyroxine sodium is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells and reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints.
CSN12271 L-Thyroxine 51-48-9 L-Thyroxine is an iodine-containing hormone produced from thyroglobulin in the thyroid follicular cells.
CSN26546 GSK5182 877387-37-6 GSK5182 is a specific inverse agonist for estrogen-related receptor γ.
CSN22842 GSK 4716 101574-65-6 GSK4716 is an agonist of ERRβ/γ with IC50 of 2 µM with similar potency as the protein ligand PGC-1α.
CSN22408 GC 14 447415-34-1 GC 14 is a selective agonist of thyroid hormone β1 activation (TRβ1) with an EC50 of 680 nM.
CSN25302 Estrogen receptor modulator 1 63676-22-2 Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM), with a pIC50 of 0.46. It has been found to be both estrogenic and antiproliferative in ER-positive endocrine-resistant breast cancer cell lines that overexpress protein kinase C alpha (PKCα).
CSN27511 ERRα antagonist-1 1072145-33-5 ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.
CSN22143 ERB-196 550997-55-2 ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist.
CSN21329 Eprotirome 355129-15-6 Eprotirome is a liver-selective thyroid hormone receptor agonist.
CSN27510 Dihydroresveratrol 58436-28-5 Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations.
CSN21522 Bifluranol 34633-34-6 Bifluranol is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that has been used as an antiandrogen in the United Kingdom in the treatment of benign prostatic hyperplasia.
CSN18837 Bazedoxifene HCl 198480-56-7 Bazedoxifene is a third generation selective estrogen receptor modulator (SERM).
CSN22351 Arzoxifene HCl 182133-27-3 Arzoxifene hydrocloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue while acting as an estrogen agonist to maintain bone density and lower serum cholesterol.
CSN28406 ARV-471 2614417-52-4 ARV-471 is the first-clinical-entered ERα PROTAC degrader with DC50 of ~1nM. It degrades clinically-relevant ESR1 variants (Y537S and D538G) and inhibits growth of cell lines expressing those variants.
CSN26189 Afimoxifene   68392-35-8 Afimoxifene is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. Afimoxifene is a potent activator of ER and has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. It has significant dose and time-dependent direct effects to alter the contractile function of isolated adult rat cardiac myocytes. This product has no specified isomer.
CSN22335 Acolbifene 182167-02-8 Acolbifene (EM652) is a fourth-generation selective estrogen receptor antagonist with a LC50 value of 22±3 nM.
CSN22105 4-Hydroxytamoxifen 68047-06-3 4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.
CSN22628 (R,R)-THC 138090-06-9 (R,R)-THC is a selective estrogen receptor ligand that agonist at ERα receptor (Ki = 9.0 nM) and antagonist at ERβ receptor (Ki = 3.6 nM).
CSN21921 (R)-Equol 221054-79-1 (R)-Equol is an agonist of both ERα and ERβ with Kis of 27.4 and 15.4 nM, respectively.
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