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Mps1
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN23148 | TC-Mps1-12 | 1206170-62-8 | TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor. |
| CSN17553 | NMS-P715 | 1202055-32-0 | NMS-P715 is the first selective, ATP-competitive and orally bioavailable MPS1 small-molecule inhibitor (IC50=8 nM) and selectively reduces cancer cell proliferation, leaving normal cells almost unaffected. |
| CSN17948 | Mps1-IN-3 | 1609584-72-6 | Mps1-IN-3 is a selective and highly potent MPS1 kinase inhibitor with an IC50 of 50 nM. |
| CSN17595 | Mps1-IN-2 | 1228817-38-6 | Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM. |
| CSN17187 | Mps1-IN-1 | 1125593-20-5 | Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor with IC50 of 367 nM, displaying > 1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk. |
| CSN26520 | Mps1-IN-1 dihydrochloride | 1883548-93-3 | Mps1-IN-1 dihydrochloride is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 367 nM and 27 nM[1]. |
| CSN22986 | Mps-BAY2a | 1382477-96-4 | Mps BAY 2a is a potent and selective Mps1 inhibitor with IC50 of 1 nM for human. |
| CSN16595 | MPI-0479605 | 1246529-32-7 | MPI-0479605 is a potent and selective ATP competitive Mps1 with IC50 value of 1.8 nM. |
| CSN23778 | CC-671 | 1618658-88-0 | CC-671 is a selective inhibitor of TTK (Mps1) and CLK2 with IC50s of 5 nM and 3 nM, respectively. |
| CSN28781 | BOS-172722 | 1578245-44-9 | BOS172722 is clinical candidate Mps1 inhibitor with IC50 value of 11nM. |
| CSN18932 | BAY1217389 | 1554458-53-5 | BAY1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM. |
| CSN17866 | Empesertib | 1443763-60-7 | BAY 1161909 inhibits Mps1 kinase activity with IC50 of < 1 nM when assay with 10 μM ATP, with IC50 of < 1.9 nM when assay with 2 mM ATP. |
| CSN15830 | AZ3146 | 1124329-14-1 | AZ3146 is a selective and potent Mps1 inhibitor with IC50 value of 35 nM. |
| CSN25527 | 1,16-Hexadecanediol | 7735-42-4 | 1,16-Hexadecanediol is a plant wax derivative. It could activate Mps1 MAP kinase pathway. |
