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Prostaglandin Receptor

Prostaglandin Receptor

货号 产品名 CAS号 信息
CSN17319 Treprostinil Sodium 289480-64-4 Treprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
CSN12127 Travoprost 157283-68-6 Travoprost is a synthetic prostaglandin F2α analog as a potent and selective FP prostaglandin receptor agonist, used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure.
CSN17247 TG6-10-1 1415716-58-3 TG6-10-1 is an antagonist of prostaglandin E2 receptor subtype EP2.
CSN17989 Terutroban 165538-40-9 Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.
CSN18419 Taprenepag 752187-80-7 Taprenepag is an agonist of prostaglandin E2 receptor with EC50 of 2.8 nM with hypotensive activity.
CSN25726 SC 51089 146033-02-5 SC-51089, also known as CID132748, is an antagonist of PGE2 and selective for the EP1 receptor subtype with antinociceptive activity.
CSN25725 SC 51322 146032-79-3 SC 51322 is an antagonist of EP1 prostanoid receptor with Ki of 13.8 nM.
CSN23716 Treprostinil 81846-19-7 Rumodolinl, a analog of prostacyclin, is an agonist of IP receptor that used clinically to treat pulmonary arterial hypertension. It is a vasodilator with antithrombotic and anti-inflammatory properties.
CSN21394 RO1138452 221529-58-4 RO1138452 is a selective antagonist of prostacyclin (IP) receptor with pKi of 9.3 ± 0.1 in human platelets.
CSN11791 Prostaglandin E2 363-24-6 Prostaglandin E2 is a natural prostaglandin and acts as a vasodilator by activating the prostaglandin E2 receptor.
CSN20322 Prostaglandin D2 41598-07-6 Prostaglandin D2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis.
CSN18259 ONO-AE3-208 402473-54-5 ONO-AE3-208 is an antagonist of EP4 with Ki of 1.3 nM and exhibits suppression the invasion and metastasis of prostate cancer cells.
CSN13430 OC000459 851723-84-7 OC000459 is a potent and selective D prostanoid receptor 2 (DP2) antagonist with IC50 of 13 nM.
CSN16851 Misoprostol 59122-46-2 Misoprostol is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion.
CSN11301 Limaprost 74397-12-9 Limaprost is a PGE1 analog and potent platelet adhesion inhibitor.
CSN18339 Laropiprant 571170-77-9 Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM and exhibits > 1,000 fold selectivity over DP2 receptor (Ki=0.75 μM).
CSN20466 L-798,106 244101-02-8 L-798106 is a potent and highly selective prostanoid EP3 receptor antagonist (Ki values are 0.3, 916, > 5000 and > 5000 nM at EP3, EP4, EP1 and EP2, respectively), and it can attenuate sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo.
CSN25731 L-161,982 147776-06-5 L-161,982 is a potent EP4 receptor antagonist with Ki value of 0.024 μM.
CSN22113 Ifetroban 143443-90-7 Ifetroban is a long-acting thromboxane A2 receptor antagonist, with antiplatelet activity.
CSN18274 GW627368 439288-66-1 GW627368 is a potent and selective competitive antagonist of prostanoid EP4 receptor (Ki= 100 nM) with additional human TP receptor affinity (Ki= 150 nM).
CSN18265 Grapiprant 415903-37-6 Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2).
CSN18130 Evatanepag 223488-57-1 Evatanepag is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.
CSN20029 Esuberaprost Sodium 88475-69-8 Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH).
CSN20026 Esuberaprost 94132-88-4 Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH).
CSN11793 Dinoprost Tromethamine 38562-01-5 Dinoprost tromethamine is a natural prostaglandin used as an abortifacient.
CSN11792 Dinoprost 551-11-1 Dinoprost is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
CSN25728 DG 041 861238-35-9 DG-041 is a potent and selective antagonist of prostanoid EP3 receptor with IC50 of 4.6 nM.
CSN21985 Decursinol angelate 130848-06-5 Decursinol angelate (DA) blocks PGE2-induced activation of the EP2 receptor signaling pathway, including the activation of PKA and the phosphorylation of CREB.
CSN25453 Cloprostenol Sodium Salt 55028-72-3 Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent, and is a PGF2α receptor agonist.
CSN26158 (+)-Cloprostenol (sodium salt) 62561-03-9 Cloprostenol is a PGF2 α analogue, working as an FP receptor agonist.
CSN17217 Bimatoprost 155206-00-1 Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension.
CSN19378 Alprostadil 745-65-3 Alprostadil is an analog of prostaglandin which is prostaglandin E1 agonist with vasodilatory properties and can be used to treat erectile dysfunction.
CSN17196 AH 6809 33458-93-4 AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors.
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