400-920-2911
上海市杨浦区翔殷路128号1号楼101
Prostaglandin Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN17319 | Treprostinil Sodium | 289480-64-4 | Treprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively. |
| CSN12127 | Travoprost | 157283-68-6 | Travoprost is a synthetic prostaglandin F2α analog as a potent and selective FP prostaglandin receptor agonist, used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. |
| CSN17247 | TG6-10-1 | 1415716-58-3 | TG6-10-1 is an antagonist of prostaglandin E2 receptor subtype EP2. |
| CSN17989 | Terutroban | 165538-40-9 | Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist. |
| CSN18419 | Taprenepag | 752187-80-7 | Taprenepag is an agonist of prostaglandin E2 receptor with EC50 of 2.8 nM with hypotensive activity. |
| CSN23716 | Treprostinil | 81846-19-7 | Rumodolinl, a analog of prostacyclin, is an agonist of IP receptor that used clinically to treat pulmonary arterial hypertension. It is a vasodilator with antithrombotic and anti-inflammatory properties. |
| CSN21394 | RO1138452 | 221529-58-4 | RO1138452 is a selective antagonist of prostacyclin (IP) receptor with pKi of 9.3 ± 0.1 in human platelets. |
| CSN11791 | Prostaglandin E2 | 363-24-6 | Prostaglandin E2 is a natural prostaglandin and acts as a vasodilator by activating the prostaglandin E2 receptor. |
| CSN20322 | Prostaglandin D2 | 41598-07-6 | Prostaglandin D2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. |
| CSN18259 | ONO-AE3-208 | 402473-54-5 | ONO-AE3-208 is an antagonist of EP4 with Ki of 1.3 nM and exhibits suppression the invasion and metastasis of prostate cancer cells. |
| CSN13430 | OC000459 | 851723-84-7 | OC000459 is a potent and selective D prostanoid receptor 2 (DP2) antagonist with IC50 of 13 nM. |
| CSN16851 | Misoprostol | 59122-46-2 | Misoprostol is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion. |
| CSN11301 | Limaprost | 74397-12-9 | Limaprost is a PGE1 analog and potent platelet adhesion inhibitor. |
| CSN18339 | Laropiprant | 571170-77-9 | Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM and exhibits > 1,000 fold selectivity over DP2 receptor (Ki=0.75 μM). |
| CSN18274 | GW627368 | 439288-66-1 | GW627368 is a potent and selective competitive antagonist of prostanoid EP4 receptor (Ki= 100 nM) with additional human TP receptor affinity (Ki= 150 nM). |
| CSN18265 | Grapiprant | 415903-37-6 | Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). |
| CSN18130 | Evatanepag | 223488-57-1 | Evatanepag is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM. |
| CSN20029 | Esuberaprost Sodium | 88475-69-8 | Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH). |
| CSN20026 | Esuberaprost | 94132-88-4 | Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH). |
| CSN11793 | Dinoprost Tromethamine | 38562-01-5 | Dinoprost tromethamine is a natural prostaglandin used as an abortifacient. |
| CSN11792 | Dinoprost | 551-11-1 | Dinoprost is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. |
| CSN25728 | DG 041 | 861238-35-9 | DG-041 is a potent and selective antagonist of prostanoid EP3 receptor with IC50 of 4.6 nM. |
| CSN25453 | Cloprostenol Sodium Salt | 55028-72-3 | Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent, and is a PGF2α receptor agonist. |
| CSN26158 | (+)-Cloprostenol (sodium salt) | 62561-03-9 | Cloprostenol is a PGF2 α analogue, working as an FP receptor agonist. |
| CSN17217 | Bimatoprost | 155206-00-1 | Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension. |
| CSN19378 | Alprostadil | 745-65-3 | Alprostadil is an analog of prostaglandin which is prostaglandin E1 agonist with vasodilatory properties and can be used to treat erectile dysfunction. |
| CSN17196 | AH 6809 | 33458-93-4 | AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors. |