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Proto-oncogene tyrosine-protein kinase MER is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the TYRO3/AXL/MER (TAM) receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN28428 | XL092 | 2367004-54-2 | XL-092 is an ATP-competitive inhibitor of multiple receptor tyrosine kinases including MET, VEGFR2, AXL and MER, with IC50 values of 15, 1.6, 3.4, and 7.2 nM, respectively, in cell-based assays. |
| CSN22060 | MRX-2843 | 1429882-07-4 | MRX-2843 is an orally available small-molecule inhibitor of both MERTK and FLT3. |
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