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NO Synthesis

货号 产品名 CAS号 信息
CSN13958 Tussilagone 104012-37-5 Tussilagone, a natural product isolated and purified from the flower of Tussilago farfara, has potential treatment of neuro-inflammatory diseases through the inhibition of overproduction of nitric oxide and prostaglandin E(2) .
CSN14406 (2S,3R,4S,5S,6R)-2-(4-Hydroxy-3-methoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 109194-60-7 Tachioside, a natural product isolated and purified from the barks of Pinus yunnanensis with antioxidant and α-glucosidase inhibitory activities, decreases lipid content in 3T3-L1 adipocytes by inhibiting lipogenesis, shows antiobesity activities., and can inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.
CSN21831 S-MTC 156719-41-4 S-MTC is a selective NOS inhibitor with selectivity toward the neuronal isoform compared to eNOS and iNOS.
CSN14822 Kazinol B 99624-27-8 Kazinol B, a natural product isolated and purified from the barks of Broussonetia papyrifera, inhibits the NO synthesis with an IC(50) of 21.6 mM, stimulates respiratory burst, is probably mediated by the synergism of PKC activation and [Ca2+]i elevation in rat neutrophils, stimulates Ca(2+) release from internal Ca(2+) store, probably through the sphingosine 1-phosphate and IP(3) signaling, activates external Ca(2+) influx mainly through a non-store-operated Ca(2+) entry (non-SOCE) pathway, and inhibits SOCE, probably attributable to a break in the Ca(2+) driven force of mitochondria.
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