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G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN26141 | YM-254890 | 568580-02-9 | YM-254890 works as both a selective inhibitor of the Gq protein subfamily and a novel platelet aggregation inhibitor with IC50 value below 0.6μM by blocking the P2Y1 receptor-signal transduction pathway. It isolated from the culture broth of strain QS3666. |
| CSN18533 | PH-064 | 892546-37-1 | PH-064 is a sodium channel inhibitor. It is also a selective Gαq inhibitor. It traps Gαq in the empty pocket conformation by permitting GDP exit but interdicting GTP entry. |
| CSN21724 | Mas7 | 145854-59-7 | Mas7, structural analogue of mastoparan isolated from wasp venom, is an activator of G protein via Gαi and Gαo stimulation. |
| CSN26651 | 0990CL | 511514-03-7 | 0990CL is a specific heterotrimeric Gαi subunit inhibitor by direct interaction with Gαi. 0990CL is able to block α2AR mediated regulation of cAMP[1]. |
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