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Transthyretin (TTR or TBPA) is a transport protein in the serum and cerebrospinal fluid that carries the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN16495 | Tafamidis | 594839-88-0 | Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. |
| CSN24476 | Tafamidis meglumine | 951395-08-7 | Tafamidis binds selectively and with negative cooperativity (K(d)s ~2 nM and ~200 nM) to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR. |
| CSN32907 | Acoramidis | 1446711-81-4 | Acoramidis inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin. |
| CSN41807 | Dichlorophenyl-ABA | 18201-65-5 | |
| CSN66784 | Acoramidis hydrochloride | 2242751-53-5 | |
| CSN67951 | Inotersen sodium | 1432726-13-0 | |
| CSN80187 | Patisiran sodium | 1386913-72-9 |
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