|((2-(6-氨基-9H-嘌呤-9-基)乙氧基)甲基)磷酸|CsnPharm

CAS No.: 106941-25-7

阿德福韦 Catalog No. CSN12481

Synonyms: GS-0393;PMEA;GS-393

Adefovir is a NRTI used for treatment of hepatitis B and herpes simplex virus infection.

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技术信息

生物活性

描述The herpesviruses comprise a large family of viruses infecting most vertebrates. The virus particle is about 100 nm in diameter and consists of an icosahedral nucleocapsid surrounded by an outer membrane. A critical defining property of the herpesviruses is their ability to form a latent infection as part of their life cycle. Adefovir has been shown to have good antiviral activity against several viruses, including HIV and HBV, and herpesviruses, such as HSV (herpes simplex virus), EBV (Epstein–Barr virus), VZV (varicella zoster virus), and CMV (cytomegalovirus). Adefovir has an IC_{50_{of 0.7 μM against HBV in the HepG2.2.15 cell line^[3]. The effect of adefovir on viral CCC DNA (covalently closed circular DNA) synthesis was examined with primary cultures of DHBV (duck HBV)-infected fetal hepatocytes. Adefovir was administered for six consecutive days starting one day before or four days after DHBV inoculation. Dose-dependent inhibition of both virion release in culture supernatants and synthesis of intracellular viral DNA was observed. Preventive treatment of experimentally infected ducklings with adefovir revealed that it efficiently suppressed viremia and intrahepatic DNA^[4]. The steady-state volume of distribution of adefovir in patients was found to be about 0.4 L/kg^[3].}}
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00798460	Chronic Hepatitis B	Phase 4	Terminated(could not enroll pa... more >>tients) Collapse <<	-	Korea, Republic of ... more >> Ilsanpaik hospital Goyang, Gyunggi, Korea, Republic of, 411-706 Collapse <<
NCT02826070	Hepatitis B, Chronic	Phase 4	Unknown	October 2017	China, Beijing ... more >> 302 Military Hospital Of China Beijing, Beijing, China Beijing Ditan Hospital Beijing, Beijing, China BeiJing YouAn Hospital ,Capital Medical University Beijing, Beijing, China Department of infectious disease, First Hospital of Peking University Beijing, Beijing, China People's Hospital of Beijing University Beijing, Beijing, China China, Chongqing The Second Affiliated of ChongQing University of Medical Science Chongqing, Chongqing, China China, Guangdong Department of Infectious Disease, Nanfang Hospital Guangzhou, Guangdong, China No. 8 People's Hospital In GuangZhou Guangzhou, Guangdong, China The Third Hospital of Sun Yat-Sen University Guangzhou, Guangdong, China China, Hubei Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan, Hubei, China China, Hunan Xiangya Hospital Central-South Univrsity Changsha, Hunan, China China, Jiangsu No.81 Hospital of PLA Nanjing, Jiangsu, China China, Jilin First Hospital .Jilin Unniversity Changchun, Jilin, China China, Liaoning ShengJing Hospital of China Medical University Shengyang, Liaoning, China China, Shandong JiNan Infectious Diseases Hospital Jinan, Shandong, China China, Shanghai Changhai Hospital affiliated to Second Military Medical University Shanghai, Shanghai, China Huashan Hospital，Fudan University Shanghai, Shanghai, China Shanghai Ruijin Hospital Shanghai, Shanghai, China China, Shanxi Tangdu Hospital XiAn, Shanxi, China China, Zhejiang The First Affiliated Hospital of College of Medicine, Zhejiang University Hangzhou, Zhejiang, China Collapse <<
NCT00199732	-	-	Completed	-	France ... more >> Service d'Hépato-gastroentérologie Limoges, France Service de Médecine Interne Limoges, France Service de Virologie Limoges, France Service des Maladies Infectieuses et Tropicales Limoges, France Collapse <<

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参考文献

[1] Hachiya A, Kodama EN, et al. K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism. PLoS One. 2011 Jan 13;6(1):e16242.
[2] Perno CF, Yarchoan R, et al. Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages. Antiviral Res. 1992 Apr;17(4):289-304.
[3] 7.11 - Deoxyribonucleic Acid Viruses: Antivirals for Herpesviruses and Hepatitis B Virus
[4] Delmas J, Schorr O, Jamard C, et al. Inhibitory effect of adefovir on viral DNA synthesis and covalently closed circular DNA formation in duck hepatitis B virus-infected hepatocytes in vivo and in vitro. Antimicrob Agents Chemother. 2002;46(2):425–433

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.6605 mL
- 18.3026 mL
- 36.6051 mL
- 5 mM
- 0.7321 mL
- 3.6605 mL
- 7.3210 mL
- 10 mM
- 0.3661 mL
- 1.8303 mL
- 3.6605 mL

技术信息

CAS号	106941-25-7	储存条件	粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C8H12N5O4P	运输	蓝冰
分子量	273.19	别名	GS-0393;PMEA;GS-393;阿德福韦

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT00798460	Chronic Hepatitis B	Phase 4	Terminated(could not enroll pa... more >>tients) Collapse <<	-	Korea, Republic of ... more >> Ilsanpaik hospital Goyang, Gyunggi, Korea, Republic of, 411-706 Collapse <<
NCT02826070	Hepatitis B, Chronic	Phase 4	Unknown	October 2017	China, Beijing ... more >> 302 Military Hospital Of China Beijing, Beijing, China Beijing Ditan Hospital Beijing, Beijing, China BeiJing YouAn Hospital ,Capital Medical University Beijing, Beijing, China Department of infectious disease, First Hospital of Peking University Beijing, Beijing, China People's Hospital of Beijing University Beijing, Beijing, China China, Chongqing The Second Affiliated of ChongQing University of Medical Science Chongqing, Chongqing, China China, Guangdong Department of Infectious Disease, Nanfang Hospital Guangzhou, Guangdong, China No. 8 People's Hospital In GuangZhou Guangzhou, Guangdong, China The Third Hospital of Sun Yat-Sen University Guangzhou, Guangdong, China China, Hubei Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan, Hubei, China China, Hunan Xiangya Hospital Central-South Univrsity Changsha, Hunan, China China, Jiangsu No.81 Hospital of PLA Nanjing, Jiangsu, China China, Jilin First Hospital .Jilin Unniversity Changchun, Jilin, China China, Liaoning ShengJing Hospital of China Medical University Shengyang, Liaoning, China China, Shandong JiNan Infectious Diseases Hospital Jinan, Shandong, China China, Shanghai Changhai Hospital affiliated to Second Military Medical University Shanghai, Shanghai, China Huashan Hospital，Fudan University Shanghai, Shanghai, China Shanghai Ruijin Hospital Shanghai, Shanghai, China China, Shanxi Tangdu Hospital XiAn, Shanxi, China China, Zhejiang The First Affiliated Hospital of College of Medicine, Zhejiang University Hangzhou, Zhejiang, China Collapse <<
NCT00199732	-	-	Completed	-	France ... more >> Service d'Hépato-gastroentérologie Limoges, France Service de Médecine Interne Limoges, France Service de Virologie Limoges, France Service des Maladies Infectieuses et Tropicales Limoges, France Collapse <<
NCT00002184	HIV Infections	Phase 2	Completed	-	United States, Arizona ... more >> Phoenix Body Positive Phoenix, Arizona, United States, 85016 United States, California Krauss Med Partners / Dept of Research and Development Los Angeles, California, United States, 90036 UCLA Care Ctr Los Angeles, California, United States, 900951793 Davies Med Ctr San Francisco, California, United States, 94114 United States, Connecticut Blick Med Associates Greenwich, Connecticut, United States, 06830 United States, District of Columbia George Washington Med Ctr Washington, District of Columbia, United States, 20037 United States, Maryland Johns Hopkins Univ School of Medicine Baltimore, Maryland, United States, 21287 United States, Massachusetts Univ of Massachusetts Med Ctr Worcester, Massachusetts, United States, 01655 United States, New York North Shore Community Hosp Manhassett, New York, United States, 11030 United States, Oklahoma Associates of Med and Mental Health Tulsa, Oklahoma, United States, 74114 United States, Pennsylvania Univ of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Rhode Island Mem Hosp of Rhode Island Pawtucket, Rhode Island, United States, 02860 United States, Texas Univ of Texas Southwestern Med Ctr of Dallas Dallas, Texas, United States, 75235 Puerto Rico Hosp Regional de Ponce - Area Vieja Ponce, Puerto Rico, 00731 San Juan AIDS Program Santruce, Puerto Rico, 00908 Collapse <<
NCT01829685	Chronic Hepatitis B ... more >> Inadequate Response Nucleos(t)Ide Analogues Treatment Collapse <<	Phase 4	Unknown	-	China, Beijing ... more >> Beijing Ditan Hospital Beijing, Beijing, China Beijing Friendship Hospital Attached To The Capital Medical University Beijing, Beijing, China Department of infectious disease, First Hospital of Peking University Beijing, Beijing, China People's Hospital Under Beijnig University Beijing, Beijing, China China, Fujian The First Affiliated Hospital of Fujian Medical University FuZhou, Fujian, China China, Guangdong The First People's Hospital of Foshan FoShan, Guangdong, China Department of Infectious Disease, Nanfang Hospital Guangzhou, Guangdong, China GuangDong Provincial People's hospital GuangZhou, Guangdong, China China, Guangxi First Affiliated Hospital of Guangxi Medical University NanNing, Guangxi, China China, Hubei Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan, Hubei, China China, Hunan Xiangya Hospital Central-South Univrsity Changsha, Hunan, China China, Jilin First Hospital .Jilin Unniversity Changchun, Jilin, China China, Liaoning ShengJing Hospital of China Medical University Shengyang, Liaoning, China China, Shanghai Changhai Hospital affiliated to Second Military Medical University Shanghai, Shanghai, China Huashan Hospital，Fudan University Shanghai, Shanghai, China Shanghai Ruijin Hospital Shanghai, Shanghai, China Collapse <<
NCT01088009	Compensated Chronic Hepatitis ... more >>B Collapse <<	Phase 4	Completed	-	-
NCT00002379	HIV Infections	Phase 2	Completed	-	United States, Arizona ... more >> Phoenix Body Positive Phoenix, Arizona, United States, 85016 United States, California AIDS Healthcare Foundation Labs Los Angeles, California, United States, 90027 Davies Med Ctr San Francisco, California, United States, 94114 United States, Connecticut Blick Med Associates Greenwich, Connecticut, United States, 06830 United States, District of Columbia George Washington Med Ctr Washington, District of Columbia, United States, 20037 United States, Illinois Cook County Gen Hosp / Division of Infect Diseases Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins Univ School of Medicine Baltimore, Maryland, United States, 21287 United States, Massachusetts Community Research Initiative Brookline, Massachusetts, United States, 02445 United States, New York Community Research Initiative on AIDS New York, New York, United States, 10001 Saint Vincent's AIDS Ctr New York, New York, United States, 10011 United States, Pennsylvania Hershey Med Ctr / Dept of Hematology Hershey, Pennsylvania, United States, 17033 United States, Rhode Island Mem Hosp of Rhode Island Pawtucket, Rhode Island, United States, 02860 United States, Texas Univ of Texas Southwestern Med Ctr of Dallas Dallas, Texas, United States, 75235 United States, Washington Swedish Med Ctr Seattle, Washington, United States, 98122 Puerto Rico Hosp Regional de Ponce - Area Vieja Ponce, Puerto Rico, 00731 Collapse <<
NCT00002234	HIV Infections	Phase 2	Completed	-	United States, California ... more >> Pacific Oaks Med Group Beverly Hills, California, United States, 90211 United States, Colorado Univ of Colorado / Health Science Ctr Denver, Colorado, United States, 80262 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Rhode Island Brown Univ School of Medicine Providence, Rhode Island, United States, 02908 United States, Virginia Hampton Roads Med Specialists Hampton, Virginia, United States, 23666 Collapse <<
NCT00307489	-	-	Completed	-	-
NCT01597934	Chronic Hepatitis B	Phase 4	Unknown	May 2014	-
NCT01300234	Hepatitis B	Phase 3	Completed	-	China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510060 GSK Investigational Site Guangzhou, Guangdong, China, 510515 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Hubei GSK Investigational Site Wuhan, Hubei, China, 430030 China, Hunan GSK Investigational Site Changsha, Hunan, China, 410008 China, Jiangsu GSK Investigational Site Nanjing, Jiangsu, China, 210003 GSK Investigational Site Nanjing, Jiangsu, China, 210029 China, Jilin GSK Investigational Site Changchun, Jilin, China, 130021 China, Sichuan GSK Investigational Site Chengdu, Sichuan, China, 610041 China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 China GSK Investigational Site Beijing, China, 100015 GSK Investigational Site Beijing, China, 100044 GSK Investigational Site Beijing, China, 100050 GSK Investigational Site Chongqing, China, 400038 GSK Investigational Site Fuzhou, China, 350025 GSK Investigational Site Jinan, China, 250021 GSK Investigational Site Shanghai, China, 200001 GSK Investigational Site Shanghai, China, 200025 GSK Investigational Site Shanghai, China, 200040 GSK Investigational Site Shanghai, China, 201508 Collapse <<
NCT01834508	Chronic Hepatitis B	Phase 4	Unknown	December 2016	-
NCT00051077	HIV Infections ... more >> Hepatitis B Hepatitis C Collapse <<	Phase 2	Withdrawn	-	-
NCT01139203	Liver Transplantation ... more >> Hepatitis B Collapse <<	Not Applicable	Unknown	-	China ... more >> Shanghai First People's Hospital Recruiting Shanghai, China, 200000 Contact: Zhi-Hai Peng, MD PHD 0086-021-63240090 ext 3132 pengpzh@hotmail.com Sub-Investigator: Tao Li, MD Collapse <<
NCT00640588	Hepatitis B, Chronic	Phase 3	Completed	-	Spain ... more >> Novartis Investigative Site Barcelona, Spain Collapse <<
NCT01300234	-	-	Completed	-	-
NCT00002220	HIV Infections	Phase 3	Completed	-	United States, California ... more >> LAC / USC Med Ctr / Infectious Diseases Los Angeles, California, United States, 90033 United States, Connecticut Yale Univ / AIDS Clinical Trials Unit New Haven, Connecticut, United States, 06510 United States, Delaware Med Ctr of Delaware Wilmington, Delaware, United States, 19899 United States, Hawaii Hawaii AIDS Clinical Trial Unit Honolulu, Hawaii, United States, 96816 United States, Illinois Rush Presbyterian Saint Lukes Med Ctr Chicago, Illinois, United States, 606123832 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 212876220 United States, Massachusetts Massachusetts Gen Hosp Boston, Massachusetts, United States, 02114 United States, New York Columbia Presbyterian Hosp New York, New York, United States, 10032 AIDS TMT Unit / Univ Hosp Stonybrook, New York, United States, 117948153 United States, Tennessee Vanderbilt Clinic Nashville, Tennessee, United States, 37212 United States, Texas Oaklawn Physicians Group Dallas, Texas, United States, 75219 Collapse <<
NCT00922207	Hepatitis B, Chronic	Phase 4	Completed	-	Taiwan ... more >> Changhua Christian Hospital; Internal Medicine Changhua, Taiwan, 500 Kaohsiung Chang Gung Memorial Hospital; Dept of Internal Medicine Kaohsiung, Taiwan, 00833 Kaohsiung Medical Uni Chung-Ho Memorial Hospital; Dept of Internal Medicine Kaohsiung, Taiwan, 807 Chang Gung Medical Foundation - Keelung; Dept. of Hepato-Gastroenterology Keelung City, Taiwan, 204 China Medical University Hospital; Department of Rheumatology Taichung, Taiwan, 404 National Taiwan Uni Hospital; Gastro-Enterology Dept. Taipei, Taiwan, 100 Taipei Veterans General Hospital; Gastroenterology Division Taipei, Taiwan, 112 Tri-Service Hospital; Dept. of Internal Medicine Taipei, Taiwan Chang Gung Medical Foundation - Linkou; Dept. of Hepato-Gastroenterology Taoyuan, Taiwan, 333 Collapse <<
NCT00307489	Chronic Hepatitis B	Phase 2	Completed	-	United States, California ... more >> San Francisco, California, United States, 94115 San Jose, California, United States, 95128 United States, New York Flushing, New York, United States, 11355 New York, New York, United States, 10013 New York, New York, United States, 10016 New York, New York, United States, 10021 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19107 United States, Virginia Fairfax, Virginia, United States, 22031 Norfolk, Virginia, United States, 23502 Richmond, Virginia, United States, 23249 France Angers, France, 49933 Clichy, France, 92110 Lille, France, 59037 Lyon, France, 69288 Marseille, France, 13285 Rouen, France, 76031 Strasbourg, France, 67091 Germany Berlin, Germany, 10969 Berlin, Germany, 13353 Bonn, Germany, 53105 Erlangen, Germany, 91054 Essen, Germany, 45122 Frankfurt, Germany, 60590 Hamburg, Germany, 20999 Hannover, Germany, 30623 Herne, Germany, 44623 Munchen, Germany, 81377 Spain Sevilla, Spain, 41014 Collapse <<
NCT00606099	Chronic Hepatitis B	Phase 4	Withdrawn(study was cancelled)	-	United States, Georgia ... more >> Novartis Atlanta, Georgia, United States, 30308 United States, New York Novartis Flushing, New York, United States, 11355 United States, Virginia Novartis Sterling, Virginia, United States, 20166 Collapse <<
NCT00002419	HIV Infections	Phase 2	Completed	-	United States, California ... more >> Pacific Oaks Med Group Beverly Hills, California, United States, 90211 United States, Colorado Univ of Colorado / Health Science Ctr Denver, Colorado, United States, 80262 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Rhode Island Brown Univ School of Medicine Providence, Rhode Island, United States, 02908 United States, Virginia Hampton Roads Med Specialists Hampton, Virginia, United States, 23666 Collapse <<
NCT00002219	HIV Infections	Phase 2	Unknown	-	United States, Florida ... more >> All Children's Hosp St. Petersburg, Florida, United States, 33731 United States, Louisiana Tulane Univ Med Ctr / Dept of Pediatrics New Orleans, Louisiana, United States, 70112 United States, New York Bronx Lebanon Hosp Ctr / Dept of Pediatrics Bronx, New York, United States, 10457 North Shore Univ Hosp / Division of Immunology Great Neck, New York, United States, 11021 St Lukes Roosevelt Hosp Ctr New York, New York, United States, 10025 United States, North Carolina Duke Univ Med Ctr / Duke South Hosp Durham, North Carolina, United States, 27710 United States, South Carolina Med Univ of South Carolina Charleston, South Carolina, United States, 29425 Collapse <<
NCT01270165	Chronic Hepatitis B	Phase 3	Unknown	May 2012	Korea, Republic of ... more >> Department of Internal Medicine, Yonsei University College of Medicine Recruiting Seoul, Korea, Republic of, 120-752 Contact: Han Jak Ryu, Dr. +82-10-2329-2379 hanjak@yuhs.ac Contact: Jun Yong Park, Dr. +82-2-2228-1994 DRPJY@yuhs.ac Collapse <<
NCT00158717	-	-	Completed	-	-
NCT01341743	Hepatitis B	Phase 4	Unknown	December 2014	China, Beijing ... more >> Beijing Ditan Hospita Beijing, Beijing, China Beijing Friendship Hospital Attached to the Capital Medical University Beijing, Beijing, China Department of infectious disease, First Hospital of Peking University BeiJing, Beijing, China People'S Hospital Under Beijnig University Beijing, Beijing, China China, Fujian The First Affiliated Hospital of Fujian Medical University FuZhou, Fujian, China China, Guangdong The First People's Hospital of Foshan FoShan, Guangdong, China Department of infectious disease, Nanfang Hospital GuangZhou, Guangdong, China GuangDong Provincial People's hospital GuangZhou, Guangdong, China China, Guangxi First Affiliated Hospital of Guangxi Medical University NanNing, Guangxi, China China, Hubei Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan, Hubei, China China, Hunan Xiangya Hospital Central-South Univrsity ChangSha, Hunan, China China, Jilin First Hospital .Jilin Unniversity ChangChun, Jilin, China China, Liaoning ShengJing Hospital of China Medical University ShenYang, Liaoning, China China, Shanghai Changhai Hospital affiliated to Second Military Medical University ShangHai, Shanghai, China Huashan Hospital，Fudan University ShangHai, Shanghai, China Shanghai Ruijin Hospital ShangHai, Shanghai, China Collapse <<
NCT00922207	-	-	Completed	-	-
NCT00117676	Chronic Hepatitis B	Phase 3	Completed	-	-
NCT00033163	HIV Infections ... more >> Hepatitis B Collapse <<	Phase 2	Completed	-	United States, California ... more >> UC Davis Medical Center Sacramento, California, United States, 95814 Univ. of California Davis Med. Ctr., ACTU Sacramento, California, United States Ucsf Aids Crs San Francisco, California, United States, 94110 United States, Colorado University of Colorado Hospital CRS Aurora, Colorado, United States, 80262 United States, Illinois Northwestern University CRS Chicago, Illinois, United States, 60611 Cook County Hosp. CORE Ctr. Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States, 21287 United States, New York Beth Israel Med. Ctr., ACTU New York, New York, United States, 10003 NY Univ. HIV/AIDS CRS New York, New York, United States, 10016 Cornell CRS New York, New York, United States, 10021 Weill Med. College of Cornell Univ., The Cornell CTU New York, New York, United States United States, Ohio Univ. of Cincinnati CRS Cincinnati, Ohio, United States, 452670405 MetroHealth CRS Cleveland, Ohio, United States, 441091998 United States, Tennessee Vanderbilt Therapeutics CRS Nashville, Tennessee, United States, 37203 United States, Washington University of Washington AIDS CRS Seattle, Washington, United States, 98104 Collapse <<
NCT03241641	Chronic Hepatitis b	Phase 4	Active, not recruiting	March 2020	Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of, 05505 Collapse <<
NCT00065507	Hepatitis B	Phase 3	Completed	-	-
NCT00002398	HIV Infections	Not Applicable	Completed	-	United States, California ... more >> Gilead Sciences Inc Foster City, California, United States, 94404 Collapse <<
NCT00116805	-	-	Completed	-	-
NCT00117676	-	-	Completed	-	-
NCT00065507	-	-	Completed	-	-
NCT00661076	Hepatitis B, Chronic	Phase 3	Completed	-	Turkey ... more >> Ankara, Turkey, 06018 Ankara, Turkey, 06100 Ankara, Turkey, 06500 Ankara, Turkey, 06800 Gaziantep, Turkey, 27310 Collapse <<
NCT00002326	HIV Infections	Phase 1	Completed	-	United States, Maryland ... more >> Natl Cancer Institute Bethesda, Maryland, United States, 20892 Collapse <<
NCT00116805	Chronic Hepatitis B	Phase 3	Completed	-	-
NCT00409019	Chronic Hepatitis B	Phase 4	Withdrawn(Study cancelled With... more >>drawn before enrollment of any participants) Collapse <<	-	-
NCT00096785	Hepatitis B C... more >>hronic Disease Collapse <<	Phase 3	Completed	-	-
NCT00496002	Chronic Hepatitis ... more >> Hepatitis B Collapse <<	Phase 3	Terminated(The study was termi... more >>nated in the interest of patient safety.) Collapse <<	-	-
NCT00096785	-	-	Completed	-	-
NCT00115245	Chronic Hepatitis B	Phase 3	Completed	-	United States, California ... more >> Los Angeles, California, United States Pasadena, California, United States San Francisco, California, United States United States, Florida Miami, Florida, United States Australia Clayton, Australia Wooloongabba, Australia Canada Calgary, Canada Toronto, Canada Winnipeg, Canada China Hong Kong, China France Paris, France Korea, Republic of Seoul, Korea, Republic of Singapore Singapore, Singapore Taiwan Taipei, Taiwan Thailand Bangkok, Thailand Collapse <<
NCT00513968	Chronic Hepatitis B	Phase 1	Completed	-	Korea, Republic of ... more >> Kangnam St. Mary's Hospital Seoul, Korea, Republic of, 137-701 Collapse <<
NCT00071201	Chronic Hepatitis B	Phase 3	Completed	-	United States, California ... more >> Gilead Sciences, Inc. 333 Lakeside Drive Foster City, California, United States, 94404 Collapse <<
NCT00023153	HIV Infections ... more >> Chronic Hepatitis B Collapse <<	Phase 3	Completed	-	United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse <<
NCT00002161	HIV Infections	Not Applicable	Completed	-	-
NCT00002426	HIV Infections	Not Applicable	Completed	-	-
NCT00605384	-	-	Terminated(Business Objectives... more >> Have Changed) Collapse <<	-	-
NCT00042393	-	-	-	-	-
NCT00410202	Hepatitis B, Chronic	Phase 3	Completed	-	-
NCT00000843	HIV Infections	Phase 1	Completed	-	United States, California ... more >> UCSF / Moffitt Hosp - Pediatric San Francisco, California, United States, 941430105 United States, Florida Univ of Florida Health Science Ctr / Pediatrics Jacksonville, Florida, United States, 32209 United States, Illinois Chicago Children's Memorial Hosp Chicago, Illinois, United States, 606143394 United States, Maryland Johns Hopkins Hosp - Pediatric Baltimore, Maryland, United States, 212874933 United States, Massachusetts Children's Hosp of Boston Boston, Massachusetts, United States, 021155724 United States, New Jersey Children's Hosp of New Jersey / UMDNJ - New Jersey Med Schl Newark, New Jersey, United States, 071072198 United States, Pennsylvania Children's Hosp of Philadelphia Philadelphia, Pennsylvania, United States, 191044318 United States, Tennessee Saint Jude Children's Research Hosp of Memphis Memphis, Tennessee, United States, 381052794 Vanderbilt Univ Med Ctr Nashville, Tennessee, United States, 372322581 Puerto Rico Univ of Puerto Rico / Univ Children's Hosp AIDS San Juan, Puerto Rico, 009365067 Collapse <<
NCT00410202	-	-	Completed	-	-
NCT00002115	HIV Infections	Phase 1	Completed	-	United States, Washington ... more >> Univ of Washington Seattle, Washington, United States, 98122 Collapse <<
NCT00002128	HIV Infections	Phase 1	Completed	-	United States, Maryland ... more >> Johns Hopkins Univ Baltimore, Maryland, United States, 21205 Collapse <<
NCT00496158	Chronic Hepatitis ... more >> Hepatitis B Collapse <<	Phase 3	Terminated(The study was termi... more >>nated in the interest of patient safety.) Collapse <<	-	-
NCT00002206	HIV Infections	Phase 1	Completed	-	United States, District of Col... more >>umbia Anderson Clinical Research Washington, District of Columbia, United States, 20037 United States, Maryland Johns Hopkins Univ Clinical Pharmacology Baltimore, Maryland, United States, 21287 United States, New York Anderson Clinical Research New York, New York, United States, 10016 United States, Pennsylvania Anderson Clinical Research Philadelphia, Pennsylvania, United States, 19107 Anderson Clinical Research / Inc Pittsburgh, Pennsylvania, United States, 15213 Collapse <<
NCT00001082	Cytomegalovirus Infections ... more >> HIV Infections Collapse <<	Phase 3	Completed	-	United States, California ... more >> Community Consortium / UCSF San Francisco, California, United States, 94110 United States, Colorado Denver CPCRA / Denver Public Hlth Denver, Colorado, United States, 80204 United States, District of Columbia Washington Reg AIDS Prog / Dept of Infect Dis Washington, District of Columbia, United States, 20422 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Illinois AIDS Research Alliance - Chicago Chicago, Illinois, United States, 60657 United States, Louisiana Louisiana Comm AIDS Rsch Prog / Tulane Univ Med New Orleans, Louisiana, United States, 70112 United States, Michigan Wayne State Univ - WSU/DMC / Univ Hlth Ctr Detroit, Michigan, United States, 48201 Henry Ford Hosp Detroit, Michigan, United States, 48202 United States, New Jersey Southern New Jersey AIDS Cln Trials / Dept of Med Camden, New Jersey, United States, 08103 North Jersey Community Research Initiative Newark, New Jersey, United States, 07103 United States, New Mexico Partners in Research / New Mexico Albuquerque, New Mexico, United States, 87131 United States, New York Harlem AIDS Treatment Grp / Harlem Hosp Ctr New York, New York, United States, 10037 United States, Oregon The Research and Education Group Portland, Oregon, United States, 97210 United States, Pennsylvania Philadelphia FIGHT Philadelphia, Pennsylvania, United States, 19107 United States, Virginia Richmond AIDS Consortium / Div of Infect Diseases Richmond, Virginia, United States, 23298 Collapse <<
NCT01639066	Chronic Viral Hepatitis B With... more >>out Delta-agent Collapse <<	Phase 4	Completed	-	Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Collapse <<
NCT00605384	Chronic Hepatitis B	Phase 3	Terminated(Business Objectives... more >> Have Changed) Collapse <<	-	United States, California ... more >> Cedars Sinai Medical Center Los Angeles, California, United States, 90048 Kaiser Permanente Medical Center San Francisco, California, United States, 94118 United States, Illinois Rush University Medical Center Chicago, Illinois, United States, 60612 United States, New York Local Institution New York, New York, United States, 10025 Belgium Local Institution Bruxelles, Belgium, 1200 Local Institution Leuven, Belgium, 3000 Germany Local Institution Berlin, Germany, 13353 Local Institution Bonn, Germany, 53105 Local Institution Duesseldorf, Germany, 40237 Local Institution Mainz, Germany, 55131 Italy Local Institution Messina, Italy, 98124 Local Institution Modena, Italy, 41100 Local Institution Naples, Italy, 80135 Local Institution Padova, Italy, 35128 Local Institution San Giovanni Rotondo, Italy, 71013 Poland Local Institution Chorzow, Poland, 41-500 Local Institution Krakow, Poland, 31-531 Local Institution Lublin, Poland, 20-089 Turkey Local Institution Ankara, Turkey, 06010 Local Institution Ankara, Turkey, 06620 Local Institution Istanbul, Turkey, 34093 Local Institution Istanbul, Turkey, 34098 Local Institution Istanbul, Turkey, 34360 Local Institution Istanbul, Turkey, 34460 Local Institution Istanbul, Turkey, 34722 Local Institution Izmir, Turkey, 35100 Local Institution Kocaeli, Turkey, 41380 Local Institution Sihhiye Ankara, Turkey, 06100 Local Institution Trabzon, Turkey, 61080 Collapse <<
NCT00753467	Hepatitis B	Phase 2	Unknown	August 2009	United States, California ... more >> Huntington Medical Research Institutes Not yet recruiting Pasadena, California, United States, 91105 Contact: Lori Tong, RN 626-397-5827 ltong@hmri.org Principal Investigator: Myron J Tong, PhD, MD Collapse <<
NCT00455091	-	-	Terminated(No cases enrollment... more >>) Collapse <<	April 2018	Taiwan ... more >> Chang-Gung Memorial Hospital Kaohsiung, Taiwan Kaohsiung Medical University Chung-Ho Memorial Hospital Kaohsiung, Taiwan Veterans General Hospital-Kaohsiung Kaohsiung, Taiwan Chang-Gung Memorial Hospital (Lin-Kou) Taichung, Taiwan Taichung Veterans General Hospital Taichung, Taiwan National Cheng Kung University Hospital Tainan, Taiwan National Taiwan University Hospital Taipei, Taiwan Veterans General Hospital-Taipei Taipei, Taiwan Collapse <<
NCT00013702	Hepatitis B H... more >>IV Infection Collapse <<	Phase 2	Completed	-	United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse <<
NCT00095121	Chronic Hepatitis B	Phase 3	Completed	-	United States, Massachusetts ... more >> Boston, Massachusetts, United States Collapse <<
NCT00230477	Hepatitis B	Phase 4	Completed	-	United States, Washington ... more >> Harborview Medical Center Seattle, Washington, United States, 98104 Collapse <<
NCT00158704	Hepatitis B	Not Applicable	Terminated(The study stopped d... more >>ue to marketing approval by the FDA.) Collapse <<	-	-
NCT00986778	Hepatitis B, Chronic	Phase 4	Withdrawn(Business Objectives ... more >>Changed) Collapse <<	June 2014	-
NCT00095121	-	-	Completed	-	-
NCT00857675	Chronic Hepatitis B	Phase 3	Completed	-	China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510515 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Jilin GSK Investigational Site Changchun, Jilin, China, 130021 China, Shandong GSK Investigational Site Jinan, Shandong, China China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 China GSK Investigational Site Beijing, China, 100011 GSK Investigational Site Beijing, China, 100044 GSK Investigational Site Chongqing, China, 400038 GSK Investigational Site Chongquin, China, 400038 GSK Investigational Site Shanghai, China, 200040 Collapse <<
NCT00316719	Chronic Hepatitis B	Phase 3	Completed	-	-
NCT01263002	Hepatitis B Associated Hepatoc... more >>ellular Carcinoma Collapse <<	Phase 4	Completed	-	Korea, Republic of ... more >> Seoul National University Hospital Seoul, Korea, Republic of Collapse <<
NCT00316719	-	-	Completed	-	-
NCT00718887	Hepatitis B, Chronic	Phase 4	Completed	-	China, Beijing ... more >> Local Institution Beijing, Beijing, China, 100011 China, Guizhou Local Institution Guiyang, Guizhou, China, 550004 China, Jiangsu Local Institution Nanjing, Jiangsu, China, 210002 China, Jiangxi Local Institution Nanchang, Jiangxi, China, 330006 China, Jilin Local Institution Changchun, Jilin, China, 130021 China, Liaoning Local Institution Shenyang, Liaoning, China, 110004 China, Shanghai Local Institution Shanghai, Shanghai, China, 200235 Local Institution Shanghai, Shanghai, China Collapse <<
NCT00704106	-	-	Unknown	December 2013	United States, California ... more >> Stanford University Medical Center Palo Alto, California, United States, 94304 San Jose Gastroenterology San Jose, California, United States, 95116 San Jose Gastroenterology San Jose, California, United States, 95128 United States, Illinois Asian Village Medical Clinic Chicago, Illinois, United States, 60640 United States, Texas Houston Gastroenterology Clinic Houston, Texas, United States, 77072 Digestive Health Associates of Texas Plano, Texas, United States, 75093 Collapse <<
NCT01581242	Healthy	Phase 1	Completed	-	Korea, Republic of ... more >> Clinical Trial Center, Seoul National University Hospital Seoul, Korea, Republic of Collapse <<
NCT00641082	HBeAg(-) Chronic Hepatitis B W... more >>ith Compensated Liver Function Collapse <<	Phase 4	Completed	-	Korea, Republic of ... more >> Seoul National University Bundang Hospital Bundang, Korea, Republic of Seoul National University Hospital Seoul, Korea, Republic of Collapse <<
NCT00307242	Chronic Hepatitis B	Phase 4	Completed	-	-
NCT01264133	Chronic Hepatitis B	Phase 4	Terminated	-	Korea, Republic of ... more >> Samsung Medical Center Seoul, Korea, Republic of Collapse <<
NCT01205165	Hepatitis B, Chronic	Phase 4	Completed	-	-
NCT00718887	-	-	Completed	-	-
NCT00023309	HBV (Hepatitis B Virus) ... more >> Hepatitis B Hepatitis Collapse <<	Phase 2	Completed	-	United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse <<
NCT01205165	-	-	Completed	-	-
NCT00645294	Hepatitis B	Phase 1 Phase 2	Completed	-	Belgium ... more >> Cliniques Universitaries Bruxelles, Belgium, 1200 Germany J.W. Goethe-Universitat Frankfurt, Germany, D-60590 Mid. Hochschule Hannover Kinderklinik Hannover, Germany, D-30625 Kinderklinik der Gutenberg Universitat Mainz, Germany, 55101 Standort Lindwurmstrasse Munchen, Germany, D-80337 Zentrum fur Kinder und Jugendmedizin der Klinikum Wuppertal, Germany, D-42282 Poland Oddzial Chorob Infekcyjnych Dzieci Krakow, Poland, 31-202 Klinika Gastroenterologii Warszawa, Poland, 04-730 United Kingdom King's College Hospital London, England, United Kingdom, SE5 9RY University of Birmingham Birmingham, United Kingdom, B4 6NH Collapse <<
NCT00023309	-	-	Completed	-	-
NCT00672867	Patients With LC-B	Phase 3	Completed	-	Korea, Republic of ... more >> Samsung Medical Center Seoul, Korea, Republic of Collapse <<
NCT00489151	Hepatitis B	Not Applicable	Unknown	December 2007	China ... more >> Queen Mary Hospital Recruiting Hong Kong, China Sub-Investigator: Raymond Liang, Prof Sub-Investigator: Yok-Lam Kwong, Prof Sub-Investigator: Wing-Yan Au, Dr Sub-Investigator: Chor-sang Chim, Dr Sub-Investigator: Louis Chow, Dr Sub-Investigator: Chee-Kin Hui, Dr Collapse <<
NCT02366247	Hepatitis B, Chronic	Phase 3	Unknown	February 2016	-
NCT00376259	Hepatitis B	Phase 3	Terminated(The study was not c... more >>ompleted as planned and was terminated early with agreement from the European Medicines Agency (EMEA)) Collapse <<	-	United States, California ... more >> Novartis San Diego, California, United States San Mateo, California, United States Hong Kong Pok Fu Lam, Hong Kong Korea, Republic of Seoul, Korea, Republic of Taiwan Novarits Kaohsuing, Taiwan Thailand Bangkok, Thailand Collapse <<
NCT00973219	Chronic Hepatitis B	Not Applicable	Unknown	November 2018	Netherlands ... more >> Academic Medical Center Amsterdam, Noord-Holland, Netherlands, 1100 AZ Collapse <<
NCT01732367	Chronic Hepatitis B	Phase 4	Completed	-	Korea, Republic of ... more >> Department of Internal Medicine, Keimyung University Dongsan Medical Center Daegu, Korea, Republic of, ASI\|KR\|KS002\|TAEGU Collapse <<
NCT00376259	-	-	Terminated(The study was not c... more >>ompleted as planned and was terminated early with agreement from the European Medicines Agency (EMEA)) Collapse <<	-	-
NCT00347009	Hepatitis B, Chronic ... more >> Cirrhosis Fibrosis Chronic Hepatitis B Collapse <<	Phase 4	Completed	-	Hong Kong ... more >> GSK Investigational Site Pokfulam, Hong Kong Korea, Republic of GSK Investigational Site Daegu, Korea, Republic of, 700-712 GSK Investigational Site Pusan, Korea, Republic of, 602-739 GSK Investigational Site Seoul, Korea, Republic of, 120-752 GSK Investigational Site Seoul, Korea, Republic of, 135-710 GSK Investigational Site Seoul, Korea, Republic of, 137-701 GSK Investigational Site Sungnam-City, Korea, Republic of, 463-712 Singapore GSK Investigational Site Singapore, Singapore, 169608 Taiwan GSK Investigational Site Kaohsiung, Taiwan, 833 GSK Investigational Site Taipei, Taiwan, 100 GSK Investigational Site Taipei, Taiwan, 114 Vietnam GSK Investigational Site Ho Chi Minh City, Vietnam Collapse <<
NCT00644761	Hepatitis B	Phase 2	Completed	-	United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California Cedars Sinai Medical Center Los Angeles, California, United States, 90048 California Pacific Medical Center San Francisco, California, United States, 94115 University of California, San Francisco San Francisco, California, United States, 94143 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, Massachusetts Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02115 United States, New York NYU Medical Center New York, New York, United States, 10016 Columbia Presbyterian Medical Center New York, New York, United States, 10032 Mayo Clinic Rochester, New York, United States, 55905 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 United States, Texas Baylor Research Institute Dallas, Texas, United States, 75204 Collapse <<
NCT00531167	Chronic Hepatitis B	Phase 4	Completed	-	Korea, Republic of ... more >> Korea University Ansan Hospital Ansan, Gyeonggi-do, Korea, Republic of Korea University Anam Hospital Seoul, Korea, Republic of Collapse <<
NCT02075294	-	-	Completed	-	China, Beijing ... more >> 302 military hospital of China Beijing, Beijing, China, 100039 Collapse <<
NCT02366208	Hepatitis B, Chronic	Phase 2	Completed	-	China, Beijing ... more >> 302 Military Hoapital of China Beijing, Beijing, China China, Hainan Hainan General Hospital Haikou, Hainan, China China, Hebei The Third Hospital of Hebei Medical University Shijiazhuang, Hebei, China China, Hunan The Second Xiangya Hospital of Central South University Changsha, Hunan, China China, Jiangsu 81 Military Hospital of China Nanjing, Jiangsu, China Jiangsu Province Hospital Nanjing, Jiangsu, China The Second Hospital of Nanjing Nanjing, Jiangsu, China China, Jilin The First Hospital of Jilin University Changchun, Jilin, China China, Liaoning The Sixth People's Hospital of Shenyang Shenyang, Liaoning, China China, Shanxi The First Affiliated Hospital of Xi'an Jiaotong University Xi'an, Shanxi, China The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an, Shanxi, China China, Sichuan West China Hospital Sichuan University Chengdu, Sichuan, China Collapse <<
NCT00371761	Hepatitis B, Chronic (CHB)	Phase 3	Completed	-	-
NCT01264354	Chronic Hepatitis B	Phase 4	Completed	-	Korea, Republic of ... more >> Samsung Medical Center Seoul, Korea, Republic of Collapse <<
NCT00371761	-	-	Completed	-	-
NCT00347009	-	-	Completed	-	-
NCT03236584	Proportion of Patients With a ... more >>Sustained Virological Response (Serum HBV DNA <20 IU/mL) at Week 48 Collapse <<	Phase 3	Active, not recruiting	March 30, 2019	-
NCT00960518	Hepatitis B Virus ... more >> Hepatocellular Carcinoma Collapse <<	Phase 2	Unknown	August 2015	China, Heilongjiang ... more >> The Fourth Affiliated Hospital of Haerbin Medical University Recruiting Ha'er'bin, Heilongjiang, China, 150001 Contact: Baozhong Shen, MD +86-451-82576888 drbaozhong.shen@gmail.com Principal Investigator: Baozhong Shen, MD China, Shanghai Shanghai 10th Hospital of Tongji University Recruiting Shanghai, Shanghai, China, 200025 Contact: Maoquan Li, MD, PhD +86-21-6630058 drmaoquan.li@gmail.com Principal Investigator: Maoquan Li, MD, PhD Collapse <<
NCT00403585	Hepatitis B, Chronic ... more >> Chronic Hepatitis B Collapse <<	Phase 4	Completed	-	Korea, Republic of ... more >> GSK Investigational Site Seoul, Korea, Republic of, 137-701 Collapse <<
NCT01436539	Chronic Hepatitis B	Phase 4	Unknown	July 2013	China ... more >> Beijing Ditan Hospital, Capital Medical University Not yet recruiting Beijing, China, 100015 Principal Investigator: Jun Cheng, post doctor Collapse <<
NCT00403585	-	-	Completed	-	-
NCT01023217	Hepatitis B, Chronic	Phase 4	Completed	-	Korea, Republic of ... more >> Asan Medical Center Seoul, the Meteropolis of Seoul, Korea, Republic of, 138-736 Collapse <<
NCT02482272	Hepatitis B, Chronic	Phase 4	Unknown	May 2017	Korea, Republic of ... more >> Asan Medical Center Recruiting Seoul, Korea, Republic of Contact: Young Hwa Chung Collapse <<
NCT00324961	Chronic Hepatitis B	Phase 4	Completed	-	China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510515 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Hubei GSK Investigational Site Wuhan, Hubei, China, 430030 China, Jiangsu GSK Investigational Site Nanjing, Jiangsu, China, 210029 China, Jilin GSK Investigational Site Changchun, Jilin, China, 130021 China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 China GSK Investigational Site Beijing, China, 100011 GSK Investigational Site Beijing, China, 100044 GSK Investigational Site Beijing, China, 100050 GSK Investigational Site Changsha, China, 410008 GSK Investigational Site Chongqing, China, 400038 GSK Investigational Site Chongquin, China, 400038 GSK Investigational Site Jinan, China, 250021 GSK Investigational Site Shanghai, China, 200001 GSK Investigational Site Shanghai, China, 200003 GSK Investigational Site Shanghai, China, 200025 GSK Investigational Site Shanghai, China, 200040 GSK Investigational Site Shanghai, China, 200433 Collapse <<
NCT01595633	Chronic Hepatitis B	Phase 4	Unknown	February 2014	Korea, Republic of ... more >> Department of Internal Medicine, Yonsei University College of Medicine Recruiting Seoul, Korea, Republic of, 120-752 Contact: BeomKyung Kim, Dr +82-2-2228-1930 beomkkim@yuhs.ac Contact: Jun Yong Park, Dr +82-2-2228-1994 DRPJY@yuhs.ac Collapse <<
NCT01023217	-	-	Completed	-	-
NCT00324961	-	-	Completed	-	-
NCT01146808	-	-	Completed	-	-
NCT00441974	Chronic Hepatitis B	Phase 4	Completed	-	China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510515 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Hubei GSK Investigational Site Wuhan, Hubei, China, 430030 China, Jiangsu GSK Investigational Site Nanjing, Jiangsu, China, 210002 GSK Investigational Site Nanjing, Jiangsu, China, 210003 GSK Investigational Site Nanjing, Jiangsu, China, 210029 China, Jilin GSK Investigational Site Changchun, Jilin, China, 130021 China, Sichuan GSK Investigational Site Chengdu, Sichuan, China, 610041 China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 China GSK Investigational Site Beijing, China, 100011 GSK Investigational Site Beijing, China, 100044 GSK Investigational Site Beijing, China, 100050 GSK Investigational Site Beijing, China, 100069 GSK Investigational Site Changsha, China, 410008 GSK Investigational Site Changsha, China, 410011 GSK Investigational Site Chongqing, China, 400038 GSK Investigational Site Chongquin, China, 400038 GSK Investigational Site Fuzhou, China, 350025 GSK Investigational Site Jinan, China, 250021 GSK Investigational Site Shanghai, China, 200001 GSK Investigational Site Shanghai, China, 200003 GSK Investigational Site Shanghai, China, 200025 GSK Investigational Site Shanghai, China, 200040 GSK Investigational Site Shanghai, China, 200433 GSK Investigational Site Tianjin, China, 300192 Collapse <<
NCT01146808	Hepatitis B L... more >>iver Transplantation Collapse <<	Phase 1 Phase 2	Completed	-	United States, New York ... more >> Center for Liver Disease and Transplantation at Columbia University Medical Center New York, New York, United States, 10032 Collapse <<
NCT01353742	Hepatitis B, Chronic	Phase 1	Completed	-	Hong Kong ... more >> GSK Investigational Site Shatin, New Territories, Hong Kong Collapse <<
NCT01491295	Chronic Hepatitis B	Phase 4	Recruiting	December 2019	Taiwan ... more >> Taipei Veterans General Hospital-Division of Gastroenterology Recruiting Taipei, Taiwan, 11217 Contact: Yi-Hsiang Huang 886-28712121 ext 3055 yhhuang@vghtpe.gov.tw Principal Investigator: Yi-Hsiang Huang Collapse <<
NCT00187746	Other Conditions That May Be A... more >> Focus of Clinical Attention Collapse <<	Phase 4	Withdrawn(Budget exceeded for ... more >>project.) Collapse <<	-	United States, California ... more >> San Francisco General Hospital San Francisco, California, United States, 94143 Collapse <<
NCT02327689	Hepatitis B, Chronic ... more >> Fibrosis Collapse <<	Phase 4	Unknown	July 2017	-
NCT00441974	-	-	Completed	-	-
NCT01863589	-	-	Completed	-	-
NCT01546116	Chronic Hepatitis B	Phase 4	Completed	-	Korea, Republic of ... more >> Chungbuk National University Hospital Cheongju, Chngcheongbuk-do, Korea, Republic of Yonsei University Wonju Christian Hospital Wonju, Gangwon-do, Korea, Republic of Hallym University, Sacred Heart Hospital Anyang, Gyeonggi-do, Korea, Republic of The Catholic University of Korea, Euijeongbu Saint Mary's Hospital Euijeongbu, Gyeonggi-do, Korea, Republic of Korea University Ansan Hospital Ansan, Gyeonggi, Korea, Republic of Gachon University Gil Medical Center Incheon, Korea, Republic of Inha University Hospital Incheon, Korea, Republic of Hallym University, Gangnam Sacred Heart Hospital Seoul, Korea, Republic of Korea University Anam Hospital Seoul, Korea, Republic of Collapse <<
NCT01329419	-	-	Completed	-	-
NCT01329419	-	-	Completed	-	-
NCT01804387	Chronic Hepatitis B	Phase 4	Unknown	May 2014	Korea, Republic of ... more >> Korea University Ansan Hospital Recruiting Ansan, Gyeonggi-do, Korea, Republic of, 425-707 Contact: Hyung Joon Yim, M.D 82-31-412-5583 gudwns21@medimail.co.kr Collapse <<

阿德福韦 Catalog No. CSN12481

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