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CAS No.: 158440-71-2
Synonyms: MGI 114;6-Hydroxymethylacylfulvene;NSC 683863
Irofulven is a DNA alkylator agent that inhibits DNA synthesis.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00003390 | Kidney Cancer | Phase 2 | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Collapse << |
NCT00003997 | Leukemia Myel... more >>odysplastic Syndromes Collapse << | Phase 1 | Completed | - | United States, Texas ... more >> University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT00003760 | Pancreatic Cancer | Phase 2 | Completed | - | United States, Nebraska ... more >> University of Nebraska Medical Center Omaha, Nebraska, United States, 68198-3330 United States, Texas Brooke Army Medical Center Fort Sam Houston, Texas, United States, 78234 San Antonio Cancer Institute San Antonio, Texas, United States, 78229 Collapse << |
实验方案
技术信息
CAS号 | 158440-71-2 | 储存条件 |
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分子式 | C15H18O3 | 运输 | 蓝冰 | |
分子量 | 246.30 | 别名 | MGI 114;6-Hydroxymethylacylfulvene;NSC 683863;Irofulven;HMAF |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00003390 | Kidney Cancer | Phase 2 | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Collapse << |
NCT00003997 | Leukemia Myel... more >>odysplastic Syndromes Collapse << | Phase 1 | Completed | - | United States, Texas ... more >> University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT00003760 | Pancreatic Cancer | Phase 2 | Completed | - | United States, Nebraska ... more >> University of Nebraska Medical Center Omaha, Nebraska, United States, 68198-3330 United States, Texas Brooke Army Medical Center Fort Sam Houston, Texas, United States, 78234 San Antonio Cancer Institute San Antonio, Texas, United States, 78229 Collapse << |
NCT00019552 | Fallopian Tube Cancer ... more >> Ovarian Cancer Primary Peritoneal Cavity Cancer Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> Medicine Branch Bethesda, Maryland, United States, 20892 Collapse << |
NCT00005031 | Endometrial Cancer | Phase 2 | Completed | - | - |
NCT00005070 | Cervical Cancer | Phase 2 | Completed | - | - |
NCT00124566 | Prostate Cancer | Phase 2 | Completed | - | - |
NCT00012038 | Brain and Central Nervous Syst... more >>em Tumors Collapse << | Phase 1 Phase 2 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Comprehensive Cancer Center Birmingham, Alabama, United States, 35294-3300 United States, Florida H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612-9497 United States, Georgia Emory University Hospital - Atlanta Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-2410 United States, Massachusetts Massachusetts General Hospital Cancer Center Boston, Massachusetts, United States, 02114 United States, Michigan Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, North Carolina Comprehensive Cancer Center at Wake Forest University Winston-Salem, North Carolina, United States, 27157-1029 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 United States, Texas University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78284-7811 Collapse << |
NCT00005968 | Melanoma (Skin) | Phase 2 | Completed | - | United States, California ... more >> John Wayne Cancer Institute Santa Monica, California, United States, 90404 United States, Colorado Veterans Affairs Medical Center - Denver Denver, Colorado, United States, 80220 University of Colorado Cancer Center Denver, Colorado, United States, 80262 United States, Illinois Lutheran General Hospital Park Ridge, Illinois, United States, 60068 United States, Missouri Ellis Fischel Cancer Center - Columbia Columbia, Missouri, United States, 65203 Collapse << |
NCT00003370 | Unspecified Childhood Solid Tu... more >>mor, Protocol Specific Collapse << | Phase 1 | Completed | - | - |
NCT00003796 | Breast Cancer | Phase 2 | Completed | - | United States, Texas ... more >> University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78229-3900 Collapse << |
NCT00062257 | Gastric Cancer | Phase 2 | Completed | - | Australia, New South Wales ... more >> Sydney Cancer Centre at Royal Prince Alfred Hospital Sydney, New South Wales, Australia, 2050 Hong Kong Prince of Wales Hospital Shatin, New Territories, Hong Kong Korea, Republic of Yonsei Cancer Center at Yonsei University Medical Center Seoul, Korea, Republic of, 120-752 Singapore Cancer Institute at National University Hospital Singapore, Singapore, 119074 Johns Hopkins - Singapore Singapore, Singapore, 119074 National Cancer Centre - Singapore Singapore, Singapore, 169610 Collapse << |
NCT00374660 | Liver Cancer | Phase 1 Phase 2 | Unknown | - | France ... more >> Bordeaux, France Clichy, France Lyon, France Nice, France Paris, France Poitiers, France Saint Cloud, France Collapse << |
NCT00053365 | Primary Peritoneal Cavity Canc... more >>er Recurrent Ovarian Epithelial Cancer Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Gynecologic Oncology Group Philadelphia, Pennsylvania, United States, 19103 Collapse << |
NCT00003666 | Lung Cancer | Phase 2 | Completed | - | - |
NCT00033735 | Pancreatic Cancer | Phase 3 | Completed | - | United States, Minnesota ... more >> MGI Pharma, Incorporated Bloomington, Minnesota, United States, 55437 Collapse << |
NCT00053365 | - | - | Completed | - | - |
NCT00003441 | Colorectal Cancer | Phase 2 | Completed | - | United States, Texas ... more >> University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT03643107 | Metastatic Castration-Resistan... more >>t Prostate Cancer Patients Collapse << | Phase 2 | Recruiting | October 2020 | Denmark ... more >> Rigshospitalet, Dept. Of Oncology Recruiting Copenhagen, Denmark, 2100 Contact: Gedske Daugaard, Professor MD +45 3545 1125 kirsten.gedske.daugaard@regionh.dk Collapse << |
NCT00003786 | Colorectal Cancer | Phase 2 | Withdrawn(NO participants) | - | United States, Illinois ... more >> University of Illinois at Chicago Chicago, Illinois, United States, 60612 University of Chicago Cancer Research Center Chicago, Illinois, United States, 60637 Louis A. Weiss Memorial Hospital Chicago, Illinois, United States, 60640 Cancer Care Specialists of Central Illinois, S.C. Decatur, Illinois, United States, 62526 Lutheran General Cancer Care Center Park Ridge, Illinois, United States, 60068 Illinois Oncology Research Association Peoria, Illinois, United States, 61602 United States, Indiana Fort Wayne Medical Oncology and Hematology, Inc. Fort Wayne, Indiana, United States, 46885-5099 Michiana Hematology/Oncology P.C. South Bend, Indiana, United States, 46617 United States, Kentucky James Graham Brown Cancer Center Louisville, Kentucky, United States, 40202 Collapse << |
NCT00124527 | Thyroid Cancer | Phase 2 | Completed | - | United States, Colorado ... more >> Aurora, Colorado, United States United States, Ohio Columbus, Ohio, United States Argentina Salta, Argentina France Lyon, France Toulouse, France Villejuif, France Peru Lima, Peru Russian Federation Moscow, Russian Federation Obninsk, Russian Federation Ukraine Kiev, Ukraine Collapse << |
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