CAS No.: 1867-73-8
N6-甲基腺苷 Catalog No. CSN13747
Synonyms: 6-Methyladenosine;N-Methyladenosine;NSC 29409
N6-Methyladenosine is an abundant nucleoside in cellular mRNA that undergoes demethylation under physiological conditions by fat mass and obesity-associated protein (FTO).
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 细胞研究
- Cell Data
- 参考文献
- [1] Adams JM, Cory S. Modified nucleosides and bizarre 5'-termini in mouse myeloma mRNA. Nature. 1975 May 1;255(5503):28-33.
- [2] Desrosiers R, Friderici K, Rottman F. Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells. Proc Natl Acad Sci U S A. 1974 Oct;71(10):3971-5.
- [3] He L, Li H, Wu A, Peng Y, Shu G, Yin G. Functions of N6-methyladenosine and its role in cancer. Mol Cancer. 2019 Dec 4;18(1):176
- [4] Niu Y, Lin Z, Wan A, Chen H, Liang H, Sun L, Wang Y, Li X, Xiong XF, Wei B, Wu X, Wan G. RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3. Mol Cancer. 2019 Mar 28;18(1):46
- [5] Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, Yi C, Lindahl T, Pan T, Yang YG, He C. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011 Oct 16;7(12):885-7
- [6] Alarcón CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF. N6-methyladenosine marks primary microRNAs for processing. Nature. 2015 Mar 26;519(7544):482-5
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1867-73-8 | 储存条件 |
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| 分子式 | C11H15N5O4 | 运输 | 蓝冰 | |||||||
| 分子量 | 281.27 | 别名 | 6-Methyladenosine;N-Methyladenosine;NSC 29409;M6A;6-Methylaminopurinosine;N6-甲基腺苷 | |||||||
| 溶解度 |
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动物实验配方 |
