CAS No.: 19309-14-9
小豆蔻明 Catalog No. CSN19898
Synonyms: (E)-Cardamomin;(E)-Alpinetin chalcone;Cardamomin
Cardamonin can supress numerous signaling pathways including TNF-α, COX-2, Wnt/β-catenin and NF-κB, suppresses melanogenesis by inhibition of Wnt/β-catenin signaling, and possesses anti-inflammatory activity via suppression of NF-kB nuclear translocation and Ik-Ba phosphorylation. It is a natural product isolated and purified from the seeds of Alpinia katsumadai Hayata.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Jaiswal S, Sharma A, et al. Gender-related pharmacokinetics and bioavailability of a novel anticancer chalcone, cardamonin, in rats determined by liquid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 1;986-987:23-30.
- [2] Kim EJ, Kim HJ, et al. Cardamonin Suppresses TGF-β1-Induced Epithelial Mesenchymal Transition via Restoring Protein Phosphatase 2A Expression. Biomol Ther (Seoul). 2015 Mar;23(2):141-8.
- [3] Li Y, Qin Y, Yang C, Zhang H, Li Y, Wu B, Huang J, Zhou X, Huang B, Yang K, Wu G. Cardamonin induces ROS-mediated G2/M phase arrest and apoptosis through inhibition of NF-κB pathway in nasopharyngeal carcinoma. Cell Death Dis. 2017 Aug 31;8(8):e3024. doi: 10.1038/cddis.2017.407. Retraction in: Cell Death Dis. 2019 Mar 27;10(4):289. PMID: 29048425; PMCID: PMC5596588.
- [4] Jia D, Tan Y, Liu H, Ooi S, Li L, Wright K, Bennett S, Addison CL, Wang L. Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo. Oncotarget. 2016 Jan 5;7(1):771-85. doi: 10.18632/oncotarget.5819. PMID: 26506421; PMCID: PMC4808032.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 19309-14-9 | 储存条件 |
|
|||
| 分子式 | C16H14O4 | 运输 | 蓝冰 | |||
| 分子量 | 270.28 | 别名 | (E)-Cardamomin;(E)-Alpinetin chalcone;Cardamomin;Cardamonin;Alpinetin chalcone;UNII-H8KP1OJ8JX;小豆蔻明 | |||
| 溶解度 |
|
动物实验配方 |
