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CAS No.: 106-24-1

香叶醇 Catalog No. CSN11092

Synonyms: 香叶醇

Geraniol is an inhibitor of glutathion S transferase with anticarcinogenic property.

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400-920-2911

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生物活性

描述Geraniol is a monoterpenic alcohol and has the activity of geraniol against prostate, bowel, liver, kidney and skin cancer. It can induce apoptosis and increase the expression of proapoptotic proteins^[3]. The treatment of geraniol inhibited the expression of IL-1β-induced PGE2, NO, COX-2, iNOS, TNF-α and IL-6. Besides, geraniol inhibited the expression of MMP-9 and ADAMTS-5, and reversed the degradation of aggrecan and type II collagen. Geraniol suppressed IL-1β-stimulated PI3K/Akt/NF-κB and MAPK activation^[4]. Histopathological examination revealed that simultaneous treatment with geraniol in AlCl3 intoxicated rats ameliorate the liver lesions such as necrosis, inflammatory cell infiltration, vacuolar degeneration, along with hyperemia and the cell density of the Langerhans islands^[5]. Geraniol significantly promoted the recovery of neuronal function and attenuated neuropathic pain after SCI(spinal cord injury) ^[6]. Geraniol (25, 50 and 100 mg/kg) exerted a depressant effect on the central nervous system of rats^[7].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 6.4830 mL
- 32.4151 mL
- 64.8301 mL
- 5 mM
- 1.2966 mL
- 6.4830 mL
- 12.9660 mL
- 10 mM
- 0.6483 mL
- 3.2415 mL
- 6.4830 mL

技术信息

CAS号

106-24-1

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C10H18O

运输

蓝冰

分子量

154.25

别名

香叶醇

溶解度

DMSO	100.0 mg/mL (648.3 mM)

动物实验配方

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