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CAS No.: 138530-94-6
Synonyms: Dexlansoprazole;T 168390;TAK-390
(R)-Lansoprazole, the dextrorotatory enantiomer of lansoprazole, can irreversibly inactivate the H+/K+-stimulated ATPase pump.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00274339 | Laryngopharyngeal Reflux | Not Applicable | Unknown | June 2008 | United States, Kentucky ... more >> Commonwealth Ear, Nose & Throat Recruiting Louisville, Kentucky, United States, 40207 Contact: Marti Gardner, MSN 502-893-0159 ext 1185 mgardner@commonwealthent.com Principal Investigator: Kenneth M Hodge, MD Sub-Investigator: John R Morris, MD Sub-Investigator: Donald V Welsh, MD Sub-Investigator: Gorden T McMurry, MD Sub-Investigator: Andrew R Gould, MD Sub-Investigator: Keith D Forwith, PhD, MD Sub-Investigator: Steven D Shotts, MD Sub-Investigator: Tamalynn O'Daniel, MSN, ARNP Sub-Investigator: Jolene H Boswell, PA-C Sub-Investigator: Mary S McLaughlin, PA-C Sub-Investigator: Martha L Gardner, MSN, ARNP Sub-Investigator: Brian Walker, PA-C Collapse << |
NCT02297126 | Adverse Drug Reaction | Not Applicable | Completed | - | United States, Indiana ... more >> Eskenazi Health System Indianapolis, Indiana, United States, 46250 Collapse << |
NCT00237679 | Voice Disorders ... more >> Gastroesophageal Reflux Collapse << | Not Applicable | Terminated(Terminated due to f... more >>unding loss.) Collapse << | - | United States, Wisconsin ... more >> University of Wisconsin Madison, Wisconsin, United States, 53792 Collapse << |
实验方案
技术信息
CAS号 | 138530-94-6 | 储存条件 |
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分子式 | C16H14F3N3O2S | 运输 | 蓝冰 | |||||||
分子量 | 369.36 | 别名 | Dexlansoprazole;T 168390;TAK-390;(+)-Lansoprazole;Dexilant;Kapidex;TAK-390MR;右旋兰索拉唑 | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00274339 | Laryngopharyngeal Reflux | Not Applicable | Unknown | June 2008 | United States, Kentucky ... more >> Commonwealth Ear, Nose & Throat Recruiting Louisville, Kentucky, United States, 40207 Contact: Marti Gardner, MSN 502-893-0159 ext 1185 mgardner@commonwealthent.com Principal Investigator: Kenneth M Hodge, MD Sub-Investigator: John R Morris, MD Sub-Investigator: Donald V Welsh, MD Sub-Investigator: Gorden T McMurry, MD Sub-Investigator: Andrew R Gould, MD Sub-Investigator: Keith D Forwith, PhD, MD Sub-Investigator: Steven D Shotts, MD Sub-Investigator: Tamalynn O'Daniel, MSN, ARNP Sub-Investigator: Jolene H Boswell, PA-C Sub-Investigator: Mary S McLaughlin, PA-C Sub-Investigator: Martha L Gardner, MSN, ARNP Sub-Investigator: Brian Walker, PA-C Collapse << |
NCT02297126 | Adverse Drug Reaction | Not Applicable | Completed | - | United States, Indiana ... more >> Eskenazi Health System Indianapolis, Indiana, United States, 46250 Collapse << |
NCT00237679 | Voice Disorders ... more >> Gastroesophageal Reflux Collapse << | Not Applicable | Terminated(Terminated due to f... more >>unding loss.) Collapse << | - | United States, Wisconsin ... more >> University of Wisconsin Madison, Wisconsin, United States, 53792 Collapse << |
NCT01922505 | - | - | Completed | - | Korea, Republic of ... more >> Seoul National University Bundang Hospital Bundang-gu, Seongnam, Gyeonggi-do, Korea, Republic of, 463-707 Collapse << |
NCT02442752 | Pediatric Gastroesophageal Ref... more >>lux Disease Collapse << | Phase 1 | Suspended(Study start date has... more >> been delayed) Collapse << | December 23, 2020 | United States, California ... more >> Children's Hospital Los Angeles Los Angeles, California, United States, 90027 United States, Kentucky University of Louisville Louisville, Kentucky, United States, 40202 United States, Maryland Johns Hopkins University School Of Medicine Baltimore, Maryland, United States, 21218 United States, Michigan Michigan Pediatric GI Center Flint, Michigan, United States, 48532 United States, Ohio Promedica Toledo Children's Hospital Toledo, Ohio, United States, 43606 United States, Texas Cook Children's Medical Center Fort Worth, Texas, United States, 76104 Israel Hadassah University Hospital - Ein Kerem Jerusalem, Israel, 9112001 Schneider Children's Medical Center Petach-Tikva, Israel, 4920235 Sheba Medical Center Ramat Gan, Israel, 5262000 Assaf Harofeh M.C Rishon Lezion, Israel, 75309 Italy Azienda Ospedaliera Universitaria "Federico II" Napoli, Italy, 80131 Umberto I Pol. di Roma-Universita di Roma La Sapienza Roma, Italy, 00161 Ospedale Pediatrico Bambino Gesu Roma, Italy, 00165 Policlinico Universitario Agostino Gemelli Roma, Italy, 00168 Mexico Centro de Investigacion Clinica Acelerada, S.C. Mexico, Distrito Federal, Mexico, 07020 Centro de Investigacion Clinica Chapultepec S.A. de C.V. Morelia, Michoacan, Mexico, 58260 Accelerium S. de R.L. de C.V. Monterrey, Nuevo Leon, Mexico, 64000 Poland Szpital Uniwersytecki nr 2 im.dr J. Biziela Bydgoszcz, Poland, 85-168 Uniwersytecki Szpital Dzieciecy w Krakowie Krakow, Poland, 30-663 Uniwersytecki Szpital Dzieciecy w Lublinie Lublin, Poland, 20-093 Szpital Wojewodzki nr 2 w Rzeszowie Rzeszow, Poland, 35-301 Instytut "Pomnik - Centrum Zdrowia Dziecka" Warszawa, Poland, 04-730 Collapse << |
NCT03050359 | Duodenal Ulcer | Phase 3 | Recruiting | June 7, 2019 | - |
NCT01129713 | Gastroesophageal Reflux Diseas... more >>e (GERD) Heartburn Indigestion Collapse << | Phase 1 Phase 2 | Unknown | May 2015 | United States, Arizona ... more >> Southern Arizona Veterans Health Care System Recruiting Tucson, Arizona, United States, 85723 Principal Investigator: Ronnie Fass, MD Collapse << |
NCT00738543 | Healthy Volunteers | Phase 3 | Completed | - | Mexico ... more >> University of Guanajuato School of Medicine Leon, Guanajuato, Mexico, 37000 Collapse << |
NCT02615184 | Erosive Esophagitis | Phase 2 | Suspended(Study start dates ha... more >>ve been delayed) Collapse << | November 16, 2019 | - |
NCT00762359 | Stomach Ulcer ... more >> Duodenal Ulcer Collapse << | Phase 3 | Terminated(AG-1749 superior to... more >> Gefarnate in ulcer prevention) Collapse << | - | - |
NCT01321125 | Infectious Diseases | Phase 3 | Completed | - | Mexico ... more >> University of Guanajuato School of Medicine Leon, Guanajuato, Mexico, 37000 Collapse << |
NCT00787254 | Stomach Ulcer ... more >> Duodenal Ulcer Collapse << | Phase 3 | Completed | - | - |
NCT00762359 | - | - | Terminated(AG-1749 superior to... more >> Gefarnate in ulcer prevention) Collapse << | - | - |
NCT00738543 | - | - | Completed | - | - |
NCT00787254 | - | - | Completed | - | - |
NCT02099708 | - | - | Completed | - | - |
NCT02099708 | - | - | Completed | - | - |
NCT03050307 | Gastric Ulcer ... more >> Peptic Ulcer Gastrointestinal Diseases Digestive System Diseases Lansoprazole Anti-Ulcer Agents Gastrointestinal Agents Proton Pump Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Collapse << | Phase 3 | Recruiting | April 19, 2019 | - |
NCT02099682 | - | - | Completed | - | - |
NCT02151786 | - | - | Completed | - | - |
NCT01131026 | Helicobacter Pylori Infection | Phase 3 | Completed | - | Turkey ... more >> Erciyes University School of Medicine Hospital, Department of Internal Medicine and Gastroenterology Kayseri, Turkey, 38039 Collapse << |
NCT02170207 | - | - | Completed | - | - |
NCT02151786 | - | - | Completed | - | - |
NCT02170207 | - | - | Completed | - | - |
NCT01990339 | - | - | Completed | - | - |
NCT02703896 | Pulmonary Aspiration of Gastri... more >>c Contents Collapse << | Phase 4 | Completed | - | - |
NCT02099682 | - | - | Completed | - | - |
NCT03488173 | Effect of Drugs ... more >> Safety Issues Collapse << | Phase 1 | Recruiting | October 2018 | China, Zhejiang ... more >> First affiliated hospital of Zhejiang University Recruiting Hangzhou, Zhejiang, China, 310003 Contact: Lihua Wu, Doctor 86 571 87236560 lihuawu73@163.com Contact: Jian Liu, Master 86 571 87236560 lindaliu87@163.com Principal Investigator: Lihua Wu Principal Investigator: Jian Liu Collapse << |
NCT03043521 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of Collapse << |
NCT01990339 | - | - | Completed | - | - |
NCT01762657 | Type 1 Diabetes | Phase 3 | Withdrawn(Study stopped prior ... more >>to Patient Enrollment) Collapse << | September 2015 | - |
NCT03079050 | GERD Proton P... more >>ump Inhibitor Collapse << | Phase 4 | Completed | - | Lebanon ... more >> American University of Beirut - Medical Center Beirut, Lebanon Collapse << |
NCT03355170 | GERD Cardiac ... more >>Event Safety Issues Collapse << | Phase 4 | Not yet recruiting | January 1, 2019 | Turkey ... more >> Başkent University Hospital Gastroenterology Dep. Not yet recruiting Adana, Turkey Contact: Birol Özer, Prof Dr birolozer@yahoo.com Çukurova University Medical Faculty Cardiology Dep. Not yet recruiting Adana, Turkey Contact: Mesut Demir, Prof Dr mdemir46@hotmail.com Ankara University Medical Faculty Gastroenterology Dep. Not yet recruiting Ankara, Turkey Contact: Mehmet Bektaş, Prof Dr Mehmet.Bektas@medicine.ankara.edu.tr Dışkapı Research and Training Hospital Gastroenterology Dep. Not yet recruiting Ankara, Turkey Contact: Elife Erarslan, Assoc Prof Dr elifeerarslan@gmail.com Yüksek İhtisas Research and Training Hospital Gastroenterology Dep. Not yet recruiting Ankara, Turkey Contact: İsmail Hakkı Kalkan, Assoc Prof Dr drismailster@gmail.com Antalya Research and Training Hospital Gastroenterology Dep. Not yet recruiting Antalya, Turkey Contact: Ayhan Hilmi Çekin, Assoc Prof Dr ayhancekin@hotmail.com Balıkesir University Medical Faculty Gastroenterology Dep. Not yet recruiting Balıkesir, Turkey Contact: Ayla Yıldız Savaş drmssa@gmail.com Gaziantep Şahinbey Research and Training Hospital Gastroenterology Dep. Not yet recruiting Gaziantep, Turkey Contact: Abdullah Emre Yıldırım, Assoc Prof Dr draemreyildirim@gmail.com Dr. Sadi Konuk Research and Training Hospital Gastroenterology Dep. Not yet recruiting Istanbul, Turkey Contact: Aliye Soylu, Prof Dr aliyesoylu@superonline.com Ümraniye Research and Training Hospital Gastroenterology Dep. Not yet recruiting Istanbul, Turkey Contact: Zuhal Çalışkan, Assoc Prof Dr caliskanzuhal@gmail.com Ege University Medical Faculty Gastroenterology Dep. Not yet recruiting İzmir, Turkey Contact: Serhat Bor, Prof Dr serhatbor@yahoo.com Tepecik Research and Training Hospital Gastroenterology Dep. Not yet recruiting İzmir, Turkey Contact: Betül Paköz, MD betulpakoz@yahoo.com Celal Bayar University Medical Faculty Gastroenterology Dep. Not yet recruiting Manisa, Turkey Contact: Elmas Kasap, Assoc Prof Dr elmaskasap@yahoo.com Sıtkı Koçman University Medical Faculty Gastroenterology Dep. Not yet recruiting Muğla, Turkey Contact: Burak Özşeker, Assoc Prof Dr burakozseker@gmail.com Recep Tayyip Erdoğan University Medical Faculty Gastroenterology Dep. Not yet recruiting Rize, Turkey Contact: Remzi Adnan Akdoğan, Assoc Prof Dr remziadnan@yahoo.com Cumhuriyet University Medical Faculty Gastroenterology Dep. Not yet recruiting Sivas, Turkey Contact: Özlem Yönem, Prof Dr ozlemyonem@gmail.com Collapse << |
NCT03488186 | Effect of Drugs ... more >> Safety Issues Collapse << | Phase 1 | Not yet recruiting | December 2018 | China, Zhejiang ... more >> First affiliated hospital of Zhejiang University Hangzhou, Zhejiang, China, 310003 Collapse << |
NCT02541786 | Helicobacter Pylori Infection | Phase 4 | Completed | - | Taiwan ... more >> Kaohsiung Medical University Hospital Kaohsiung, Taiwan, 807 Kaohsiung Veterans General Hospital Kaohsiung, Taiwan, 813 Collapse << |
NCT01568944 | Chronic Periodontitis | Not Applicable | Completed | - | United States, Georgia ... more >> GHSU-CDM Clinical Research Center Augusta, Georgia, United States, 30912 Collapse << |
靶点 | Description | IC50 |
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