|3-(4-苯氧基苯基)-1-(哌啶-3-基)-1H-吡唑并[3,4-d]嘧啶-4-胺盐酸盐|CsnPharm

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CAS No.: 1807619-60-8

(Rac)-IBT6A hydrochloride/(Rac)-依鲁替尼 Catalog No. CSN19157

Btk inhibitor 1 HCl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.

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描述Btk inhibitor 1 hydrochloride is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01611090	Chronic Lymphocytic Leukemia ... more >> Small Lymphocytic Lymphoma Collapse <<	Phase 3	Active, not recruiting	January 23, 2019	-
NCT01776840	Mantle Cell Lymphoma	Phase 3	Active, not recruiting	October 12, 2021	-
NCT02747732	Diffuse Large B Cell Lymphoma ... more >> Primary Mediastinal (Thymic) Large B-cell Lymphoma Transformed Indolent Lymphoma Recurrent Disease Refractory Cancer Collapse <<	Phase 2	Recruiting	October 2021	Israel ... more >> Dr. Meirav Kedmi Not yet recruiting Ramat Gan, Israel, 5262179 Contact: Meirav Kedmi, MD mailto:Meirav.Kedmi@sheba.health.gov.il Contact: Aliza Ackerstein, MASTER Aliza.Ackerstein@sheba.health.gov.il Sheba medical organization Recruiting Ramat Gan, Israel Contact: Meirav Kedmi, MD 972-3-530-2127 Meirav.kedmi@sheba.health.gov.il Contact: Aliza Ackerstein, Msc 972-3-5308402 aliza.ackerstein@sheba.health.gov.il Collapse <<

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实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.3646 mL
- 11.8228 mL
- 23.6457 mL
- 5 mM
- 0.4729 mL
- 2.3646 mL
- 4.7291 mL
- 10 mM
- 0.2365 mL
- 1.1823 mL
- 2.3646 mL

技术信息

CAS号	1807619-60-8		储存条件	粉末液体 -20°C:3-6 月 -80°C:12月
分子式	C22H23ClN6O		运输	蓝冰
分子量	422.91		别名

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01611090	Chronic Lymphocytic Leukemia ... more >> Small Lymphocytic Lymphoma Collapse <<	Phase 3	Active, not recruiting	January 23, 2019	-
NCT01776840	Mantle Cell Lymphoma	Phase 3	Active, not recruiting	October 12, 2021	-
NCT02747732	Diffuse Large B Cell Lymphoma ... more >> Primary Mediastinal (Thymic) Large B-cell Lymphoma Transformed Indolent Lymphoma Recurrent Disease Refractory Cancer Collapse <<	Phase 2	Recruiting	October 2021	Israel ... more >> Dr. Meirav Kedmi Not yet recruiting Ramat Gan, Israel, 5262179 Contact: Meirav Kedmi, MD mailto:Meirav.Kedmi@sheba.health.gov.il Contact: Aliza Ackerstein, MASTER Aliza.Ackerstein@sheba.health.gov.il Sheba medical organization Recruiting Ramat Gan, Israel Contact: Meirav Kedmi, MD 972-3-530-2127 Meirav.kedmi@sheba.health.gov.il Contact: Aliza Ackerstein, Msc 972-3-5308402 aliza.ackerstein@sheba.health.gov.il Collapse <<
NCT03220022	AIDS-Related Lymphoma ... more >> Ann Arbor Stage II Diffuse Large B-Cell Lymphoma Ann Arbor Stage III Diffuse Large B-Cell Lymphoma Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma CD20 Negative CD20 Positive Human Immunodeficiency Virus Positive Collapse <<	Phase 1	Recruiting	September 18, 2020	United States, California ... more >> UC San Diego Moores Cancer Center Recruiting La Jolla, California, United States, 92093 Contact: Ida C. Wong-Sefidan 858-552-8585 ext 7106 icwong@ucsd.edu Principal Investigator: Ida C. Wong-Sefidan UCLA / Jonsson Comprehensive Cancer Center Recruiting Los Angeles, California, United States, 90095 Contact: Ronald T. Mitsuyasu 310-825-6689 rmitsuya@mednet.ucla.edu Principal Investigator: Ronald T. Mitsuyasu UCSF Medical Center-Parnassus Recruiting San Francisco, California, United States, 94143 Contact: Lawrence D. Kaplan 415-353-2661 LKaplan@ucsf.edu Principal Investigator: Lawrence D. Kaplan United States, Illinois John H Stroger Jr Hospital of Cook County Recruiting Chicago, Illinois, United States, 60612 Contact: Paul G. Rubinstein 312-864-7277 prubinstein@cookcountyhhs.org Principal Investigator: Paul G. Rubinstein United States, Maryland Johns Hopkins University/Sidney Kimmel Cancer Center Recruiting Baltimore, Maryland, United States, 21287 Contact: Richard F. Ambinder 410-955-8839 ambinri@jhmi.edu Principal Investigator: Richard F. Ambinder United States, Missouri Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Lee Ratner 314-747-7405 lratner@wustl.edu Principal Investigator: Lee Ratner United States, New York Montefiore Medical Center - Moses Campus Recruiting Bronx, New York, United States, 10467 Contact: Murali Janakiram 718-920-4826 mjanakir@montefiore.org Principal Investigator: Murali Janakiram Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Ariela Noy 212-639-7423 noya@mskcc.org Principal Investigator: Ariela Noy United States, North Carolina UNC Lineberger Comprehensive Cancer Center Recruiting Chapel Hill, North Carolina, United States, 27599 Contact: Christopher E. Dittus 919-962-8565 chris_dittus@med.unc.edu Principal Investigator: Christopher E. Dittus United States, Ohio Ohio State University Comprehensive Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Robert A. Baiocchi 614-293-3196 Robert.Baiocchi@osumc.edu Principal Investigator: Robert A. Baiocchi United States, Pennsylvania Pennsylvania Oncology Hematology Associates Recruiting Philadelphia, Pennsylvania, United States, 19106 Contact: Douglas F. Beach 215-829-6307 douglas.beach@uphs.upenn.edu Principal Investigator: Douglas F. Beach Fox Chase Cancer Center Recruiting Philadelphia, Pennsylvania, United States, 19111 Contact: Stefan K. Barta 215-728-2674 Stefan.barta@fccc.edu Principal Investigator: Stefan K. Barta United States, Washington Virginia Mason Medical Center Recruiting Seattle, Washington, United States, 98101 Contact: David M. Aboulafia 206-223-6193 hemda@vmmc.org Principal Investigator: David M. Aboulafia Harborview Medical Center Recruiting Seattle, Washington, United States, 98104 Contact: Manoj P. Menon 206-667-4636 mmenon@fredhutch.org Principal Investigator: Manoj P. Menon Collapse <<
NCT03336333	Chronic Lymphocytic Leukemia ... more >> Small Lymphocytic Lymphoma Collapse <<	Phase 3	Recruiting	October 2022	-
NCT01479842	Extranodal Marginal Zone B-cel... more >>l Lymphoma of Mucosa-associated Lymphoid Tissue Nodal Marginal Zone B-cell Lymphoma Recurrent Adult Diffuse Large Cell Lymphoma Recurrent Grade 1 Follicular Lymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Grade 3 Follicular Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Marginal Zone Lymphoma Splenic Marginal Zone Lymphoma Waldenstrom Macroglobulinemia Collapse <<	Phase 1	Active, not recruiting	December 31, 2018	United States, Ohio ... more >> Ohio State University Medical Center Columbus, Ohio, United States, 43210 Collapse <<
NCT01886872	CD19 Positive ... more >> CD20 Positive CD5 Positive Stage I Chronic Lymphocytic Leukemia Stage II Chronic Lymphocytic Leukemia Stage III Chronic Lymphocytic Leukemia Stage IV Chronic Lymphocytic Leukemia Collapse <<	Phase 3	Active, not recruiting	-	-
NCT01841723	Hairy Cell Leukemia ... more >> Hairy Cell Leukemia Variant Collapse <<	Phase 2	Recruiting	-	United States, Maryland ... more >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: Robert J. Kreitman 301-451-5765 kreitmar@mail.nih.gov Principal Investigator: Robert J. Kreitman United States, Michigan Wayne State University/Karmanos Cancer Institute Recruiting Detroit, Michigan, United States, 48201 Contact: Charles A. Schiffer 313-576-8720 schiffer@karmanos.org Principal Investigator: Charles A. Schiffer United States, Minnesota Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 Contact: Timothy G. Call 507-538-0591 call.timothy@mayo.edu Principal Investigator: Timothy G. Call United States, Ohio Ohio State University Comprehensive Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Kerry A. Rogers 800-293-5066 Principal Investigator: Kerry A. Rogers United States, Texas M D Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Farhad Ravandi-Kashani 713-745-0394 fravandi@mdanderson.org Principal Investigator: Farhad Ravandi-Kashani Collapse <<
NCT02109224	Adult B Acute Lymphoblastic Le... more >>ukemia Chronic Lymphocytic Leukemia Cutaneous B-Cell Non-Hodgkin Lymphoma Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue HIV Infection Intraocular Lymphoma Multicentric Angiofollicular Lymphoid Hyperplasia Nodal Marginal Zone Lymphoma Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Burkitt Lymphoma Recurrent Adult Diffuse Large Cell Lymphoma Recurrent Adult Diffuse Mixed Cell Lymphoma Recurrent Adult Diffuse Small Cleaved Cell Lymphoma Recurrent Adult Grade III Lymphomatoid Granulomatosis Recurrent Adult Immunoblastic Lymphoma Recurrent Adult Lymphoblastic Lymphoma Recurrent Grade 1 Follicular Lymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Grade 3 Follicular Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Marginal Zone Lymphoma Recurrent Small Lymphocytic Lymphoma Refractory Chronic Lymphocytic Leukemia Refractory Hairy Cell Leukemia Refractory Plasma Cell Myeloma Small Intestinal Lymphoma Splenic Marginal Zone Lymphoma Testicular Lymphoma Waldenstrom Macroglobulinemia Collapse <<	Phase 1	Terminated(Inadequate accrual ... more >>rate) Collapse <<	-	United States, California ... more >> UCLA Center for Clinical AIDS Research and Education Los Angeles, California, United States, 90035 United States, Maryland Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland, United States, 21287 United States, Missouri Siteman Cancer Center at Washington University Saint Louis, Missouri, United States, 63110 United States, New York Albert Einstein College of Medicine Bronx, New York, United States, 10461 Montefiore Medical Center-Einstein Campus Bronx, New York, United States, 10461 Montefiore Medical Center - Moses Campus Bronx, New York, United States, 10467-2490 Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 Collapse <<
NCT03053440	Waldenström's Macroglobulinemi... more >>a Collapse <<	Phase 3	Active, not recruiting	June 2021	-

总药量计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 动物数量只每天给药次给药天

需要的总药量：mg

工作液计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 给药体积μL

您需要配制的工作液浓度为：mg/mL

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