CAS No.: 84680-54-6
依那普利拉水合物 Catalog No. CSN10907
Synonyms: MK-422;MK-422 Dihydrate;Enalaprilat (hydrate)
Enalaprilat is the first dicarboxylate-containing ACE inhibitor with IC50 of 1.94 nM, which is the active metabolite of enalapril.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Zou K, Maeda T, et al. Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme. J Biol Chem. 2009 Nov 13;284(46):31914-20.
- [2] Ceconi C, Francolini G, et al. Angiotensin-converting enzyme (ACE) inhibitors have different selectivity for bradykinin binding sites of human somatic ACE. Eur J Pharmacol. 2007 Dec 22;577(1-3):1-6. Epub 2007 Aug 3.
- [3] Ceconi C, Francolini G, Olivares A, Comini L, Bachetti T, Ferrari R. Angiotensin-converting enzyme (ACE) inhibitors have different selectivity for bradykinin binding sites of human somatic ACE. Eur J Pharmacol. 2007 Dec 22;577(1-3):1-6
- [4] van Eickels M, Vetter H, Grohé C. Angiotensin-converting enzyme (ACE) inhibition attenuates insulin-like growth factor-I (IGF-I) induced cardiac fibroblast proliferation. Br J Pharmacol. 2000 Dec;131(8):1592-6
- [5] Schumacher J, Puchakayala MR, Binkowski K, Eichler W, Dendorfer A, Klotz KF. Effects of candesartan and enalaprilat on the organ-specific microvascular permeability during haemorrhagic shock in rats. Br J Anaesth. 2006 Apr;96(4):437-43
- [6] Mangiacapra F, Peace AJ, Di Serafino L, Pyxaras SA, Bartunek J, Wyffels E, Heyndrickx GR, Wijns W, De Bruyne B, Barbato E. Intracoronary EnalaPrilat to Reduce MICROvascular Damage During Percutaneous Coronary Intervention (ProMicro) study. J Am Coll Cardiol. 2013 Feb 12;61(6):615-21
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 84680-54-6 | 储存条件 |
|
|||||
| 分子式 | C18H28N2O7 | 运输 | 蓝冰 | |||||
| 分子量 | 384.42 | 别名 | MK-422;MK-422 Dihydrate;Enalaprilat (hydrate);依那普利拉二水合物 | |||||
| 溶解度 |
|
动物实验配方 |
