CAS No.: 99755-59-6
罗替戈汀 Catalog No. CSN11867
Synonyms: N-0437;N-0923;SPM 962
Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00666965 - - Completed - - NCT02138357 Restless Legs Syndrome Phase 4 Withdrawn(No funding) - United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Collapse << NCT00537485 Early Parkinson's Disease Phase 2 Phase 3 Completed - Japan ... more >> Chubu region, Japan Hokkaido region, Japan Kanto region, Japan Kinki region, Japan Kyushu region, Japan Tohoku region, Japan Collapse << - 更多
- 参考文献
- [1] Wood M, Dubois V, et al. Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors. Br J Pharmacol. 2015 Feb;172(4):1124-35.
- [2] Scheller D, Ullmer C, et al. The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jan;379(1):73-86.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 99755-59-6 | 储存条件 |
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| 分子式 | C19H25NOS | 运输 | 蓝冰 | |
| 分子量 | 315.47 | 别名 | N-0437;N-0923;SPM 962;罗替戈汀 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT00666965 | - | - | Completed | - | - |
| NCT02138357 | Restless Legs Syndrome | Phase 4 | Withdrawn(No funding) | - | United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Collapse << |
| NCT00537485 | Early Parkinson's Disease | Phase 2 Phase 3 | Completed | - | Japan ... more >> Chubu region, Japan Hokkaido region, Japan Kanto region, Japan Kinki region, Japan Kyushu region, Japan Tohoku region, Japan Collapse << |
| NCT00537485 | - | - | Completed | - | - |
| NCT00282152 | - | - | Completed | - | - |
| NCT01628848 | Parkinson's Disease | Phase 2 | Completed | - | Japan ... more >> Chubu Region, Japan Hokkaido Region, Japan Kanto Region, Japan Kinki Region, Japan Kyushu Region, Japan Shikoku Region, Japan Tohoku Region, Japan Collapse << |
| NCT02339064 | Idiopathic Parkinson's Disease | Phase 3 | Active, not recruiting | October 2019 | United States, Arizona ... more >> Phoenix, Arizona, United States, 85013 United States, California Loma Linda, California, United States, 92354 Los Angeles, California, United States, 90033 Los Angeles, California, United States, 90095 United States, Colorado Aurora, Colorado, United States, 80045 Englewood, Colorado, United States, 80113 United States, Florida Boca Raton, Florida, United States, 33486 United States, Georgia Atlanta, Georgia, United States, 30329 Augusta, Georgia, United States, 30912 United States, Illinois Chicago, Illinois, United States, 60611 Chicago, Illinois, United States, 60612 United States, Kansas Kansas City, Kansas, United States, 66160 United States, Michigan West Bloomfield, Michigan, United States, 48322 United States, New York Albany, New York, United States, 12208 United States, Ohio Cincinnati, Ohio, United States, 45219 United States, Oregon Portland, Oregon, United States, 97239 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19107 United States, Washington Kirkland, Washington, United States, 98034 Collapse << |
| NCT00282152 | Parkinson's Disease | Not Applicable | Completed | - | - |
| NCT01631812 | Parkinson's Disease | Phase 2 | Completed | - | Japan ... more >> Chubu Region, Japan Hokkaido Region, Japan Kanto Region, Japan Kinki Region, Japan Kyushu Region, Japan Shikoku Region, Japan Tohoku Region, Japan Collapse << |
| NCT00265733 | Breast Cancer | Phase 2 | Completed | - | - |
| NCT01628848 | - | - | Completed | - | - |
| NCT02670161 | Brain Tumors ... more >>Epilepsy Migraine Mild Cognitive Impairment Concussion Multiple Sclerosis Neuropathy Parkinson's Restless Legs Syndrome Stroke Collapse << | Phase 4 | Enrolling by invitation | April 2020 | - |
| NCT01737931 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Seoul National University Bundang Hospital Kyeonggi-do, Korea, Republic of Seoul National University Hospital Seoul, Korea, Republic of Collapse << |
| NCT01737931 | - | - | Completed | - | - |
| NCT00977184 | Parkinson Disease | Phase 1 Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00977184 | - | - | Completed | - | - |
| NCT01017601 | - | - | Terminated(Interim analysis de... more >>clared futility.) Collapse << | - | - |
| NCT01017601 | Lung Cancer | Phase 2 | Terminated(Interim analysis de... more >>clared futility.) Collapse << | - | - |
| NCT01631812 | - | - | Completed | - | - |
| NCT01703832 | Acute Stress Reaction | Phase 1 Phase 2 | Completed | - | Germany ... more >> Institut fur Medizinische Psychologie und Verhaltensimmunbiologie Universitatsklinikum Essen Essen, Germany, 45122 Klinische Psychologie und Psychotherapie, Fachbereich Psychologie, Universität Marburg Marburg, Germany, 35032 Collapse << |
| NCT01703819 | Acute Stress Reaction | Phase 1 Phase 2 | Completed | - | Germany ... more >> Institut fur Medizinische Psychologie und Verhaltensimmunbiologie Universitatsklinikum Essen Essen, Germany, 45122 Klinische Psychologie und Psychotherapie, Fachbereich Psychologie, Universität Marburg Marburg, Germany, 35032 Collapse << |
| NCT01554306 | - | - | Terminated(difficulty to inclu... more >>de enough subjects) Collapse << | - | Netherlands ... more >> Sleep Medicine Centre Kempenhaeghe Heeze, Netherlands, 5591 VE Collapse << |
| NCT01703819 | - | - | Completed | - | - |
| NCT01703832 | - | - | Completed | - | - |
| NCT01628965 | Parkinson's Disease | Phase 2 Phase 3 | Completed | - | Japan ... more >> Chubu Region, Japan Hokkaido Region, Japan Kanto Region, Japan Kinki Region, Japan Kyushu Region, Japan Shikoku Region, Japan Tohoku Region, Japan Collapse << |
| NCT00666965 | Idiopathic Restless Legs Syndr... more >>ome Collapse << | Phase 2 | Completed | - | Japan ... more >> Chubu region, Japan Chugoku region, Japan Hokkaido region, Japan Kanto region, Japan Kinki region, Japan Kyushu region, Japan Shikoku region, Japan Tohoku region, Japan Collapse << |
| NCT01631825 | Parkinson's Disease | Phase 3 | Completed | - | Japan ... more >> Chubu Region, Japan Chugoku Region, Japan Hokkaido Region, Japan Kanto Region, Japan Kinki Region, Japan Kyushu Region, Japan Shikoku Region, Japan Tohoku Region, Japan Collapse << |
| NCT00001931 | Parkinson Disease | Phase 2 | Completed | - | United States, Maryland ... more >> National Institute of Neurological Disorders and Stroke (NINDS) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT01631825 | - | - | Completed | - | - |
| NCT01634243 | Parkinson's Disease | Phase 2 | Completed | - | Japan ... more >> Kanto Region, Japan Kinki Region, Japan Kyushu Region, Japan Shikoku Region, Japan Tohoku Region, Japan Collapse << |
| NCT01562743 | Idiopathic Restless Legs Syndr... more >>ome Collapse << | Phase 2 | Completed | - | - |
| NCT01562743 | - | - | Completed | - | - |
| NCT02055274 | Parkinson's Disease | Phase 1 | Completed | - | United States, California ... more >> Collaborative Neuroscience Network LLC Long Beach, California, United States, 90806 United States, Florida Compass Research LLC Orlando, Florida, United States, 32806 United States, Georgia West Georgia Sleep Disorders Center and Neurology Associates Douglasville, Georgia, United States, 30134 United States, Michigan Quest Research Institute Bingham Farms, Michigan, United States, 48025 United States, New Jersey PRA - CRI Lifetree Marlton, New Jersey, United States, 08053 Collapse << |
| NCT03589066 | Parkinson Disease | Phase 1 | Completed | - | United States, Florida ... more >> MD Clinical Hallandale Beach, Florida, United States, 33009 United States, Georgia Atlanta Center for Medical Research Atlanta, Georgia, United States, 30331 Collapse << |
| NCT00243971 | Parkinson's Disease | Phase 3 | Completed | - | Germany ... more >> Schwarz Monheim, Germany Collapse << |
| NCT02579473 | Parkinson's Disease | Phase 1 | Active, not recruiting | December 31, 2019 | United States, Alabama ... more >> University of Alabama Birmingham Birmingham, Alabama, United States, 35233 United States, Florida MD Clinical Hallandale Beach, Florida, United States, 33009 United States, Georgia Georgia Regents University Augusta, Georgia, United States, 30912 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00243217 | Idiopathic Restless Leg Syndro... more >>me Collapse << | Phase 2 | Completed | - | Germany ... more >> Schwarz Monheim, Germany Collapse << |
| NCT02227355 | - | - | Completed | - | - |
| NCT01628965 | - | - | Completed | - | - |
| NCT00599339 | - | - | Completed | - | - |
| NCT00599339 | - | - | Completed | - | - |
| NCT00244387 | Parkinson Disease, Idiopathic | Phase 3 | Completed | - | Germany ... more >> Schwarz Monheim, Germany Collapse << |
| NCT03103919 | Parkinson´s Disease | Phase 4 | Completed | - | United States, California ... more >> Pd0049 105 Fountain Valley, California, United States, 92708 United States, Florida Pd0049 102 Boca Raton, Florida, United States, 33486 United States, Illinois Pd0049 108 Winfield, Illinois, United States, 60190 United States, Kansas Pd0049 103 Kansas City, Kansas, United States, 66160 United States, New York Pd0049 106 Commack, New York, United States, 11725 United States, Oklahoma Pd0049 104 Tulsa, Oklahoma, United States, 74136 United States, South Carolina Pd0049 107 Greenville, South Carolina, United States, 29615 United States, Texas Pd0049 109 Houston, Texas, United States, 77030 Collapse << |
| NCT01159691 | - | - | Completed | - | Germany ... more >> 02 Berlin, Germany 24 Bochum, Germany 38 Buchholz, Germany 30 Erbach, Germany 14 Gera, Germany 28 Goettingen, Germany 16 Karlstadt, Germany 7 Köln, Germany 40 Lauf an der Pegnitz, Germany 39 Lüneburg, Germany 37 München, Germany 31 Neuburg, Germany 35 Nürnberg, Germany 22 Schriesheim, Germany 34 Schwäbisch Gmünd, Germany 21 Stadtroda, Germany 12 Stuttgart, Germany 36 Stuttgart, Germany 1 Ulm, Germany 32 Ulm, Germany 29 Wolfratshausen, Germany Collapse << |
| NCT01634243 | - | - | Completed | - | - |
| NCT01159691 | - | - | Completed | - | - |
| NCT01606670 | - | - | Completed | - | Austria ... more >> 61 Feldbach, Austria 60 Linz, Austria Germany 16 Altenholz, Germany 5 Alzenau, Germany 22 Bad Honnef, Germany 26 Bad Krozingen, Germany 10 Berlin, Germany 4 Dresden, Germany 34 Düsseldorf, Germany 38 Erbach, Germany 24 Freiburg, Germany 1 Gera, Germany 3 Goettingen, Germany 32 Hamburg, Germany 2 Heidenheim, Germany 11 Konigsbruck, Germany 20 Köln, Germany 15 Mühldorf Am Inn, Germany 33 Münster, Germany 35 Osnabrück, Germany 31 Ruesselsheim, Germany 7 Schriesheim, Germany 44 Senftenberg, Germany 12 Stadtroda, Germany 13 Ulm, Germany 41 Westerstede, Germany 37 Würzburg, Germany Collapse << |
| NCT01386944 | - | - | Completed | - | Germany ... more >> 12 Berlin, Germany 4 Bremen, Germany 18 Dresden, Germany 20 Flensburg, Germany 1 Kassel, Germany 11 Marburg, Germany 17 Marburg, Germany 2 Mönchengladbach, Germany 6 Münster, Germany 7 Regensburg, Germany 21 Remscheid, Germany 15 Schriesheim, Germany 10 Schwalmstadt, Germany 3 Schwerin, Germany 8 Tuebingen, Germany 16 Ulm, Germany 9 Ulm, Germany 19 Westerstede, Germany Collapse << |
| NCT01113710 | - | - | Completed | - | - |
| NCT01386944 | - | - | Completed | - | - |
| NCT01606670 | - | - | Completed | - | - |
| NCT01113710 | - | - | Completed | - | - |
| NCT00135993 | Restless Legs Syndrome | Phase 3 | Completed | - | United States, North Carolina ... more >> Schwarz RTP, North Carolina, United States Collapse << |
| NCT00136045 | Restless Legs Syndrome | Phase 3 | Completed | - | Germany ... more >> Schwarz Monheim, Germany Collapse << |
| NCT00275236 | Restless Legs Syndrome | Phase 3 | Completed | - | Germany ... more >> Schwarz BioSciences Monheim, Germany Collapse << |
| NCT00242008 | Parkinson's Disease | Phase 3 | Completed | - | United States, North Carolina ... more >> Schwarz RTP, North Carolina, United States Collapse << |
| NCT01504529 | - | - | Completed | - | - |
| NCT00263068 | Restless Legs Syndrome | Phase 3 | Completed | - | United States, North Carolina ... more >> Schwarz RTP, North Carolina, United States Collapse << |
| NCT02365870 | Anxiety Disorders ... more >> Parkinson Disease Collapse << | Phase 4 | Recruiting | January 2019 | United States, Maryland ... more >> Johns Hopkins University School of Medicine Recruiting Baltimore, Maryland, United States, 21287 Contact: Kate Perepezko, MSPH 410-614-1242 kperepe1@jhu.edu Contact: Gregory Pontone, MD 410 502-0477 gponton1@jhmi.edu Principal Investigator: Gregory Pontone, MD Collapse << |
| NCT00498108 | Idiopathic Restless Legs Syndr... more >>ome Collapse << | Phase 3 | Completed | - | Germany ... more >> Kassel, Germany, 34128 Collapse << |
| NCT00243945 | IDIOPATHIC PARKINSON'S DISEASE | Phase 3 | Completed | - | Germany ... more >> Schwarz Monheim, Germany Collapse << |
| NCT03733561 | Parkinson Disease | Phase 1 | Recruiting | December 25, 2018 | United States, Maryland ... more >> Pharmaron CPC, Inc. Recruiting Baltimore, Maryland, United States, 21201 Contact: Bobbi Horne 410-706-8818 Bobbi.Horne@pharmaron-us.com Principal Investigator: Mohamed Al-Ibrahim, MD Collapse << |
| NCT02786667 | Parkinson Disease ... more >> Apathy Collapse << | Phase 3 | Active, not recruiting | December 2017 | France ... more >> University Hospital of Grenoble Grenoble, France, 38043 Collapse << |
| NCT00663338 | Right Hemisphere Stroke ... more >> Hemispatial Neglect Motor Deficit Collapse << | Phase 2 | Completed | - | United Kingdom ... more >> Homerton University Hospital London, United Kingdom, E9 6SR Charing Cross Hospital London, United Kingdom, W68RF The National Hospital for Neurology & Neurosurgery London, United Kingdom, WC1N 3BG Collapse << |
| NCT01519882 | Advanced Idiopathic Parkinson'... more >>s Disease Collapse << | Phase 4 | Terminated(Due to major recrui... more >>tment issues, a decision was made to terminate this trial) Collapse << | - | United Kingdom ... more >> 1 Middlesborough, United Kingdom Collapse << |
| NCT00292227 | - | - | Completed | - | - |
| NCT00522379 | Parkinson's Disease | Phase 3 | Completed | - | - |
| NCT00296192 | Parkinson's Disease | Phase 2 | Completed | - | - |
| NCT03250741 | Alzheimer Disease | Phase 2 | Recruiting | June 2018 | Italy ... more >> Santa Lucia Foundation Recruiting Rome, Italy, 00179 Contact: Sonia Bonnì Collapse << |
| NCT00292227 | Parkinson's Disease | Phase 1 | Completed | - | South Africa ... more >> Farmovs-Parexel (Pty) Ltd Bloemfontein, South Africa Qdot, a division of Parexel International DA (Pty) Ltd. George, South Africa Collapse << |
| NCT00296192 | - | - | Completed | - | - |
| NCT01519882 | - | - | Terminated(Due to major recrui... more >>tment issues, a decision was made to terminate this trial) Collapse << | - | - |
| NCT01646255 | Idiopathic Parkinson's Disease | Phase 3 | Completed | - | China ... more >> Sp1037 001 Beijing, China Sp1037 002 Beijing, China Sp1037 019 Beijing, China Sp1037 025 Beijing, China Sp1037 017 Changchun, China Sp1037 007 Chengdu, China Sp1037 027 Chengdu, China Sp1037 021 Fuzhou, China Sp1037 010 Guangzhou, China Sp1037 011 Guangzhou, China Sp1037 014 Guangzhou, China Sp1037 015 Guangzhou, China Sp1037 005 Hangzhou, China Sp1037 013 Hangzhou, China Sp1037 018 Hangzhou, China Sp1037 023 Jinan, China Sp1037 003 Shanghai, China Sp1037 004 Shanghai, China Sp1037 009 Shanghai, China Sp1037 008 Suzhou, China Sp1037 016 Tianjin, China Sp1037 006 Wuhan, China Sp1037 022 Wuhan, China Sp1037 024 Wuhan, China Collapse << |
| NCT03098368 | Nocturnal Hypokinesia | Phase 4 | Active, not recruiting | May 2018 | - |
| NCT01455012 | Restless Legs Syndrome | Phase 4 | Completed | - | Germany ... more >> Berlin, Germany Kassel, Germany Marburg, Germany München, Germany Münster, Germany Schwerin, Germany Collapse << |
| NCT00522379 | - | - | Completed | - | - |
| NCT00498186 | Restless Legs Syndrome | Phase 2 | Completed | - | Austria ... more >> Innsbruck, Austria Germany Bamberg, Germany Berlin, Germany Bielefeld, Germany Gelsenkirchen, Germany Gera, Germany Halle, Germany Jena, Germany Kassel, Germany Köthen, Germany Marburg, Germany, 35039 Mittweida, Germany München, Germany Neubrandenburg, Germany Oldenburg, Germany Regensburg, Germany Schwalmstadt-Treysa, Germany Schwerin, Germany Tuttlingen, Germany Ulm, Germany Unterhaching, Germany Spain Alcira, Valencia, Spain Barcelona, Spain Madrid, Spain Collapse << |
| NCT01646255 | - | - | Completed | - | - |
| NCT01498120 | - | - | Completed | - | - |
| NCT01455012 | - | - | Completed | - | - |
| NCT01498120 | Restless Legs Syndrome | Phase 2 | Completed | - | United States, California ... more >> 012 Los Angeles, California, United States 009 Orange, California, United States United States, Florida 014 Spring Hill, Florida, United States United States, Indiana 013 Indianapolis, Indiana, United States United States, Louisiana 001 Destrehan, Louisiana, United States Collapse << |
| NCT00498186 | - | - | Completed | - | - |
| NCT00389831 | Restless Legs Syndrome | Phase 2 | Completed | - | Germany ... more >> Schwarz BioSciences GmbH Monheim, Germany Collapse << |
| NCT00389831 | - | - | Completed | - | - |
| NCT00464737 | - | - | Completed | - | - |
| NCT02100176 | - | - | Unknown | June 2014 | Italy ... more >> Ospedale Generale di Zona "Moriggia-Pelascini" Recruiting Gravedona, Como, Italy, 22015 Contact: Giuseppe Ferrazzoli, MD +39034492552 frazzittag62@gmail.com Riabilitazione Neuromotoria, Istituto Scientifico di Montescano Recruiting Montescano, Pavia, Italy, 27040 Contact: Giuseppe Frazzitta, MD +39034492552 frazzittag62@gmail.com Collapse << |
| NCT00594464 | Parkinson's Disease | Phase 4 | Completed | - | Germany ... more >> Augsburg, Germany Bochum, Germany Bonn, Germany Bremerhaven, Germany Dortmund, Germany Dresden, Germany Hanau, Germany Ingolstadt, Germany Kiel, Germany Schwerin, Germany Stralsund, Germany Ulm, Germany Collapse << |
| NCT01782222 | - | - | Completed | - | - |
| NCT00594464 | - | - | Completed | - | - |
| NCT01646268 | IDIOPATHIC PARKINSON'S DISEASE | Phase 3 | Completed | - | China ... more >> 001 Beijing, China 002 Beijing, China 019 Beijing, China 025 Beijing, China 017 Changchun, China 007 Chengdu, China 027 Chengdu, China 021 Fuzhou, China 010 Guangzhou, China 011 Guangzhou, China 014 Guangzhou, China 015 Guangzhou, China 005 Hangzhou, China 013 Hangzhou, China 018 Hangzhou, China 023 Jinan, China 003 Shanghai, China 004 Shanghai, China 009 Shanghai, China 008 Suzhou, China 016 Tianjin, China 006 Wuhan, China 022 Wuhan, China 024 Wuhan, China Collapse << |
| NCT01782222 | Idiopathic Parkinson's Disease | Phase 4 | Completed | - | - |
| NCT01523301 | - | - | Completed | - | - |
| NCT01523301 | Idiopathic Parkinson's Disease | Phase 4 | Completed | - | Korea, Republic of ... more >> 03 Ansan, Korea, Republic of 19 Anyang, Korea, Republic of 08 Busan, Korea, Republic of 26 Busan, Korea, Republic of 23 Chungbuk, Korea, Republic of 04 Daegu, Korea, Republic of 05 Daegu, Korea, Republic of 16 Daejon, Korea, Republic of 28 Goyang, Korea, Republic of 24 Gwangju, Korea, Republic of 29 Gwangju, Korea, Republic of 11 Gyeonggi-Do, Korea, Republic of 15 Jinju, Korea, Republic of 01 Seoul, Korea, Republic of 02 Seoul, Korea, Republic of 06 Seoul, Korea, Republic of 07 Seoul, Korea, Republic of 09 Seoul, Korea, Republic of 10 Seoul, Korea, Republic of 12 Seoul, Korea, Republic of 13 Seoul, Korea, Republic of 14 Seoul, Korea, Republic of 17 Seoul, Korea, Republic of 18 Seoul, Korea, Republic of 20 Seoul, Korea, Republic of 21 Seoul, Korea, Republic of 22 Seoul, Korea, Republic of 27 Seoul, Korea, Republic of 25 Yangsan, Korea, Republic of Collapse << |
| NCT00464737 | Fibromyalgia Syndrome | Phase 2 | Completed | - | - |
| NCT01744496 | Advanced Idiopathic Parkinson'... more >>s Disease Collapse << | Phase 4 | Completed | - | United States, Arizona ... more >> 2113 Gilbert, Arizona, United States United States, California 2120 Sunnyvale, California, United States United States, Florida 2109 Tampa, Florida, United States United States, Illinois 2107 Chicago, Illinois, United States United States, Kentucky 2102 Lexington, Kentucky, United States United States, North Carolina 2118 Advance, North Carolina, United States United States, Ohio 2117 Cincinnati, Ohio, United States United States, Oklahoma 2103 Tulsa, Oklahoma, United States United States, Virginia 2101 Roanoke, Virginia, United States United States, Wisconsin 2104 Milwaukee, Wisconsin, United States Germany 1204 Gera, Germany Poland 1607 Gdansk, Poland 1603 Krakow, Poland 1609 Olsztyn, Poland Slovakia 1804 Bratislava, Slovakia 1805 Dubnica Nad Vahom, Slovakia Collapse << |
| NCT01646268 | - | - | Completed | - | - |
| NCT00593606 | - | - | Completed | - | - |
| NCT00474058 | Parkinson's Disease | Phase 3 | Completed | - | - |
| NCT01744496 | - | - | Completed | - | - |
| NCT00593606 | Parkinson's Disease | Phase 3 | Completed | - | - |
| NCT02727205 | Bioequivalence - Irritation an... more >>d Sensitization Potential of Transdermal Patch Collapse << | Phase 1 | Completed | - | United States, Florida ... more >> Clinical Pharmacology of Miami, Inc. Miami, Florida, United States, 33014 Canada, Ontario Inflamax Research Inc. Mississauga, Ontario, Canada, L4W 1A4 Collapse << |
| NCT00474058 | - | - | Completed | - | - |
| NCT02103465 | Parkinson's Disease | Phase 2 | Terminated(Because the rate of... more >> recruitment was very slow) Collapse << | - | Italy ... more >> Ospedale Lorenzo Bonomo Andria Andria, Andria-Barletta-Trani, Italy, 76123 Ospedale Generale Regionale "F. Miulli" Acquaviva Delle Fonti, Bari, Italy, 70021 Ospedale S. Giacomo Monopoli, Bari, Italy, 70043 IRCCS "Casa Sollievo della Sofferenza" San Giovanni Rotondo, Foggia, Italy, 71013 Ospedale Francesco Ferrari Casarano, Lecce, Italy, 73042 A.O. Ospedale "Card. G. Panico" di Tricase Tricase, Lecce, Italy, 73039 Azienda Ospedaliera Universitaria Consorziale Policlinico di Bari Bari, Italy, 70124 Ospedale "A. Perrino" Brindisi, Italy, 72100 A.O. Universitaria "Ospedali Riuniti" - U.O. Neurologia Ospedaliera Foggia, Italy, 71100 A.O. Universitaria "Ospedali Riuniti"-U.O. Neurologia Universitaria Foggia, Italy, 71100 Presidio Ospedaliero "Vito Fazzi" Lecce, Italy, 73100 Collapse << |
| NCT01300819 | Idiopathic Parkinson's Disease | Phase 4 | Completed | - | - |
| NCT01338896 | Parkinson's Disease | Phase 1 | Completed | - | Austria ... more >> Innsbruck, Austria Wien, Austria Germany Alzenau, Germany Berlin, Germany Boblingen, Germany Bochum, Germany Gera, Germany Karlstadt, Germany Koln, Germany Stuttgart, Germany Wolfach, Germany United Kingdom Blackpool, United Kingdom Derby, United Kingdom Liverpool, United Kingdom Newcastle Upon Tyne, United Kingdom Norwich, United Kingdom Collapse << |
| NCT02123979 | Post-op Pain | Phase 2 | Unknown | January 2017 | United States, North Carolina ... more >> School of Dental Medicine At East Carolina University Not yet recruiting Greenville, North Carolina, United States, 27834 Contact: Raymond Dionne 252-744-2108 dionner@ecu.edu Principal Investigator: Raymond Dionne, DDS, PhD Collapse << |
| NCT01300819 | - | - | Completed | - | - |
| NCT01330290 | - | - | Completed | - | - |
| NCT00594386 | - | - | Completed | - | - |
| NCT00519532 | Parkinson's Disease | Phase 3 | Terminated(Due to clinical tri... more >>al supplies shortage) Collapse << | - | United States, Florida ... more >> St. Petersburg, Florida, United States, 33701 United States, North Carolina Salisbury, North Carolina, United States, 28144 Australia Concord, Australia Finland Oulu, Finland, 90220 Germany Berlin, Germany, 10713 Dresden, Germany, 01307 Kassel, Germany, 34128 Marburg, Germany, 35039 Naumburg, Germany, 06618 Ulm, Germany, 89081 Hungary Budapest, Hungary, 1145 Nyiregyhaza, Hungary, 4400 Italy Chieti, Italy Milano, Italy, 20127 New Zealand Christchurch, New Zealand Poland Olyszytn, Poland South Africa Cape Town, South Africa Spain Barcelona, Spain Madrid, Spain United Kingdom Lancashire, United Kingdom Liverpool, United Kingdom, L9 7JL Collapse << |
| NCT02070796 | Healthy | Phase 1 | Completed | - | China ... more >> 1 Hong Kong, China Collapse << |
| NCT00594386 | Parkinson's Disease | Phase 3 | Completed | - | - |
| NCT02230904 | Parkinson's Disease | Phase 1 | Completed | - | Germany ... more >> 104 Alzenau, Germany 106 Aschaffenburg, Germany 105 Berlin, Germany 107 Böblingen, Germany 111 Düsseldorf, Germany 109 Erbach, Germany 110 Essen, Germany 102 Karlstadt, Germany 101 Köln, Germany 103 Stuttgart, Germany 108 Würzburg, Germany Collapse << |
| NCT01537042 | - | - | Completed | - | - |
| NCT00519532 | - | - | Terminated(Due to clinical tri... more >>al supplies shortage) Collapse << | - | - |
| NCT01675024 | Healthy | Phase 1 | Completed | - | China ... more >> Shanghai, China Collapse << |
| NCT00501969 | Advanced Stage Parkinson's Dis... more >>ease Collapse << | Phase 3 | Completed | - | - |
| NCT01330290 | - | - | Completed | - | - |
| NCT00505687 | Idiopathic Parkinson's Disease | Phase 3 | Completed | - | - |
| NCT00505687 | - | - | Completed | - | - |
| NCT02230904 | - | - | Completed | - | - |
| NCT00599196 | Early Stage Parkinson's Diseas... more >>e Collapse << | Phase 3 | Completed | - | - |
| NCT00599196 | - | - | Completed | - | - |
| NCT00501969 | - | - | Completed | - | - |
| NCT01495793 | - | - | Completed | - | - |
| NCT01823770 | Restless Legs Syndrome (RLS) | Phase 4 | Completed | - | France ... more >> UH Montpellier Montpellier, France, 34295 Collapse << |
| NCT01537042 | Restless Legs Syndrome ... more >> End-Stage Renal Disease Collapse << | Phase 3 | Completed | - | United States, Florida ... more >> 606 Brandon, Florida, United States United States, Massachusetts 604 Newton, Massachusetts, United States United States, New York 603 West Seneca, New York, United States United States, Ohio 607 Dublin, Ohio, United States United States, Pennsylvania 605 West Chester, Pennsylvania, United States United States, Texas 601 Austin, Texas, United States Austria 101 Innsbruck, Austria Finland 201 Helsinki, Finland 203 Tampere, Finland France 302 Bordeaux Cedex, France 301 Montpellier Cédex 5, France Germany 404 Berlin, Germany 401 Marburg, Germany 402 Schwerin, Germany Italy 502 Pisa, Italy Collapse << |
| NCT00881894 | Healthy | Phase 1 | Completed | - | Germany ... more >> Neuss, NRW, Germany Collapse << |
| NCT00594165 | - | - | Completed | - | - |
| NCT01495793 | Restless Legs Syndrome | Phase 2 | Completed | - | United States, Arkansas ... more >> Sp1004 006 Little Rock, Arkansas, United States United States, California Sp1004 012 Los Angeles, California, United States Sp1004 009 Orange, California, United States United States, District of Columbia Sp1004 005 Washington, District of Columbia, United States United States, Florida Sp1004 014 Spring Hill, Florida, United States United States, Indiana Sp1004 013 Indianapolis, Indiana, United States United States, Louisiana Sp1004 001 Destrehan, Louisiana, United States United States, Missouri Sp1004 015 Saint Louis, Missouri, United States United States, New York Sp1004 007 West Seneca, New York, United States United States, Ohio Sp1004 002 Cincinnati, Ohio, United States United States, Pennsylvania Sp1004 016 West Chester, Pennsylvania, United States United States, Texas Sp1004 003 Austin, Texas, United States Collapse << |
| NCT01854216 | Healthy | Phase 1 | Completed | - | Germany ... more >> 1 Neuss, Germany Collapse << |
| NCT02728947 | Parkinson's Disease | Phase 1 | Completed | - | United States, California ... more >> CNS Network Long Beach, California, United States, 90806 United States, Florida MD Clinical Hallandale Beach, Florida, United States, 33009 United States, Georgia Atlanta Center for Medical Research Atlanta, Georgia, United States, 30331 Collapse << |
| NCT00594165 | Early-Stage Parkinson's Diseas... more >>e Collapse << | Phase 3 | Completed | - | - |
| NCT01569464 | Restless Legs Syndrome | Phase 3 | Completed | - | United States, Alabama ... more >> 006 Birmingham, Alabama, United States 013 Jasper, Alabama, United States United States, Arizona 021 Gilbert, Arizona, United States United States, Arkansas 014 Little Rock, Arkansas, United States United States, California 010 Oceanside, California, United States 004 Orange, California, United States United States, Florida 002 Tampa, Florida, United States United States, Georgia 012 Macon, Georgia, United States United States, Louisiana 008 Destrehan, Louisiana, United States United States, Massachusetts 017 Brighton, Massachusetts, United States 016 Brockton, Massachusetts, United States United States, Michigan 019 Kalamazoo, Michigan, United States United States, Missouri 015 St. Louis, Missouri, United States United States, New York 007 West Seneca, New York, United States United States, Ohio 018 Cincinnati, Ohio, United States United States, Pennsylvania 009 West Chester, Pennsylvania, United States United States, Texas 003 Austin, Texas, United States 005 San Antonio, Texas, United States Collapse << |
| NCT00957944 | - | - | Completed | - | - |
| NCT00957944 | Healthy Volunteers | Phase 1 | Completed | - | Germany ... more >> Neuss, NRW, Germany Collapse << |
| NCT01536015 | - | - | Terminated(The study was stopp... more >>ed due to low enrollment.) Collapse << | - | - |
| NCT01536015 | Advanced Parkinson's Disease | Phase 3 | Terminated(The study was stopp... more >>ed due to low enrollment.) Collapse << | - | - |
| NCT00881894 | - | - | Completed | - | - |
| NCT01059903 | Healthy Volunteers | Phase 1 | Completed | - | Germany ... more >> Moenchengladbach, NRW, Germany Collapse << |
| NCT01059903 | - | - | Completed | - | - |
| NCT01964573 | Parkinson's Disease | Phase 1 | Completed | - | Korea, Republic of ... more >> Seoul, Korea, Republic of Collapse << |
| NCT01711866 | - | - | Completed | - | - |
| NCT01569464 | - | - | Completed | - | - |
| NCT01565018 | Healthy Volunteers | Phase 1 | Completed | - | Germany ... more >> 1 Neuss, Germany Collapse << |
| NCT01761526 | Healthy | Phase 1 | Completed | - | Germany ... more >> 01 Neuss, Germany Collapse << |
| NCT01723904 | Advanced Parkinson's Disease | Phase 3 | Completed | - | Australia, New South Wales ... more >> 402 Chatswood, New South Wales, Australia 401 Sydney, New South Wales, Australia Australia, Victoria 403 Melbourne, Victoria, Australia Korea, Republic of 104 Busan, Korea, Republic of 112 Busan, Korea, Republic of 109 Daegu, Korea, Republic of 111 Gyeonggi-Do, Korea, Republic of 101 Seoul, Korea, Republic of 102 Seoul, Korea, Republic of 103 Seoul, Korea, Republic of 105 Seoul, Korea, Republic of 107 Seoul, Korea, Republic of 108 Seoul, Korea, Republic of 110 Seoul, Korea, Republic of Malaysia 202 Kuala Terengganu, Malaysia 204 Kuching Sarawak, Malaysia 201 Pulau Pinang, Malaysia Singapore 501 Singapore, Singapore 502 Singapore, Singapore Taiwan 302 Taichung, Taiwan 303 Tainan, Taiwan 306 Taipei, Taiwan Collapse << |
| NCT01711866 | Advanced Idiopathic Parkinson'... more >>s Disease Collapse << | Phase 4 | Completed | - | United States, Alabama ... more >> 505 Anniston, Alabama, United States United States, Florida 506 Atlantis, Florida, United States 508 Miami Springs, Florida, United States United States, Georgia 502 Atlanta, Georgia, United States United States, Ohio 501 Dayton, Ohio, United States United States, Oklahoma 509 Oklahoma City, Oklahoma, United States Korea, Republic of 101 Busan, Korea, Republic of 102 Busan, Korea, Republic of 108 Daegu, Korea, Republic of 109 Daegu, Korea, Republic of 105 Gyeonggi-Do, Korea, Republic of 103 Seoul, Korea, Republic of 104 Seoul, Korea, Republic of 106 Seoul, Korea, Republic of 107 Seoul, Korea, Republic of Malaysia 202 Sarawak, Malaysia Singapore 401 Singapore, Singapore 403 Singapore, Singapore Taiwan 301 Linkou, Taiwan 304 Taichung, Taiwan 305 Taipei, Taiwan Collapse << |
| NCT01723904 | - | - | Completed | - | - |
| NCT01095484 | - | - | Completed | - | - |
| NCT01976871 | - | - | Completed | - | - |
| NCT03728933 | Restless Legs Syndrome | Phase 3 | Not yet recruiting | June 2020 | - |
| NCT01976871 | Restless Legs Syndrome ... more >> Ekbom Syndrome Willis-Ekbom Disease Collapse << | Phase 4 | Completed | - | United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Collapse << |
