CAS No.: 1189561-66-7
(S)-Gossypol (acetic acid) Catalog No. CSN17536
Synonyms: (S)-(+)-Gossypol acetic acid
(S)-Gossypol acetic acid is an inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01285635 - - Terminated(drug is no longer m... more >>anufactured) Collapse << - - NCT01285635 Squamous Cell Carcinoma of the... more >> Head and Neck (SCCHN) Collapse << Phase 2 Terminated(drug is no longer m... more >>anufactured) Collapse << - United States, Michigan ... more >> University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109 Barbara Ann Karmanos Cancer Institute Detroit, Michigan, United States, 48201 Collapse << - 参考文献
- [1] Guo Z, Zhao J, et al. [Gossypol acetic acid induces DNA double-strand breaks in human mucoepidermoid carcinoma cell MEC-1] . Sheng Li Xue Bao. 2011 Apr 25;63(2):164-70. Chinese.
- [2] Wu T, Sha Y, et al. [Effects of gossypol acetic acid on human ejaculated sperm Ca2+ influx and rat vas deferens contraction action] . Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1996 Oct;18(5):375-9. Chinese.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1189561-66-7 | 储存条件 |
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| 分子式 | C32H34O10 | 运输 | 蓝冰 | |
| 分子量 | 578.61 | 别名 | (S)-(+)-Gossypol acetic acid |
