CAS No.: 1265916-41-3
(Z)-3-(((3-((Dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide Catalog No. CSN17644
Synonyms: BIX02189 Z-Isomer
BIX02189 is a selective MEK5/ERK5 inhibitor with an IC50 of 59 nM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Obara Y, Nemoto W, et al. Basic fibroblast growth factor promotes glial cell-derived neurotrophic factor gene expression mediated by activation of ERK5 in rat C6 glioma cells. Cell Signal. 2011 Apr;23(4):666-72.
- [2] Tatake RJ, O'Neill MM, et al. Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochem Biophys Res Commun. 2008 Dec 5;377(1):120-5.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1265916-41-3 | 储存条件 |
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| 分子式 | C27H28N4O2 | 运输 | 蓝冰 | |||
| 分子量 | 440.54 | 别名 | BIX02189 Z-Isomer | |||
| 溶解度 |
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动物实验配方 |
