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CAS No.: 294-90-6
Synonyms: 1;4;7
Cyclen compounds are capable of selectively binding cations and used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02718976 | Hip Fractures ... more >> Anesthesia, Local Pain, Postoperative Collapse << | Phase 2 | Completed | - | - |
NCT00709189 | Female Contraception ... more >> Contraception Therapeutic Equivalency Pharmacokinetics Collapse << | Phase 1 | Completed | - | - |
NCT02593370 | Hip Fractures ... more >> Anesthesia Local Pain, Perioperative Collapse << | Phase 1 | Completed | - | Denmark ... more >> Department of Anesthesiology and Intensive Care, Aarhus University Hospital Aarhus C, Denmark, 8000 Collapse << |
实验方案
技术信息
CAS号 | 294-90-6 | 储存条件 |
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分子式 | C8H20N4 | 运输 | 蓝冰 | |
分子量 | 172.27 | 别名 | 1;4;7;10-tetraazacyclododecane;1,4,7,10-Tetraazacyclododecane;轮环藤宁 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02718976 | Hip Fractures ... more >> Anesthesia, Local Pain, Postoperative Collapse << | Phase 2 | Completed | - | - |
NCT00709189 | Female Contraception ... more >> Contraception Therapeutic Equivalency Pharmacokinetics Collapse << | Phase 1 | Completed | - | - |
NCT02593370 | Hip Fractures ... more >> Anesthesia Local Pain, Perioperative Collapse << | Phase 1 | Completed | - | Denmark ... more >> Department of Anesthesiology and Intensive Care, Aarhus University Hospital Aarhus C, Denmark, 8000 Collapse << |
NCT00709644 | Pharmacokinetics ... more >> Therapeutic Equivalency Contraceptives, Oral Collapse << | Phase 1 | Completed | - | - |
NCT03000036 | Breast Cancer Female ... more >> Doxorubicin Induced Cardiomyopathy Collapse << | Not Applicable | Completed | - | Brazil ... more >> State University of Campinas Campinas, São Paulo, Brazil, 13083-887 Collapse << |
NCT02286258 | Renal Insufficiency, Chronic ... more >> Kidney Diseases Collapse << | Phase 1 Phase 2 | Terminated(The study was suspe... more >>nded after a suspected unexpected serious adverse event.) Collapse << | - | France ... more >> Hopital Europeen Georges Pompidou (centre d'investigations cliniques) Paris, France, 75015 Hopital Europeen Georges Pompidou (Service de Nephrologie) Paris, France, 75015 Hopital Europeen Georges Pompidou (service de Physiologie et des Radioisotopes) Paris, France, 75015 CHU Rangueil (service explorations fonctionnelles physiologiques) Toulouse, France, 31059 Collapse << |
NCT01956812 | Metastatic Pancreatic Cancer ... more >> Pancreatic Cancer Collapse << | Phase 3 | Terminated(The DSMB conducted ... more >>an interim analysis on overall survival, which showed that the treatment arm did not demonstrate a sufficient improvement in OS vs. placebo.) Collapse << | March 2017 | - |
NCT01806740 | Hepatocellular Carcinoma | Phase 4 | Active, not recruiting | April 2018 | Korea, Republic of ... more >> Guerbet Korea Seoul, Gangnam Gu, Korea, Republic of, 135-920 Collapse << |
NCT02844530 | CD22+ Relapsed/Refractory B-AL... more >>L Collapse << | Phase 2 | Withdrawn | - | France ... more >> CHU de Clermont-Ferrand Clermont-Ferrand, France, 63000 Collapse << |
NCT02382380 | Renal Dysfunction | Phase 4 | Recruiting | July 2020 | United States, Illinois ... more >> Loyola University Medical Center Recruiting Maywood, Illinois, United States, 60153 Contact: Ari Goldberg, MD 708-216-2229 argoldberg@lumc.edu Collapse << |
NCT03773133 | Small Cell Lung Cancer and Bre... more >>ast Cancer Collapse << | Phase 1 Phase 2 | Not yet recruiting | November 24, 2023 | United States, Massachusetts ... more >> Dana Farber Cancer Institute Not yet recruiting Boston, Massachusetts, United States, 02215 United States, Texas MD Anderson Cancer Center Not yet recruiting Houston, Texas, United States, 77030 Austria Medical University of Innsbruck Not yet recruiting Innsbruck, Austria, 6020 Belgium University Hospital (UZ) Leuven Not yet recruiting Leuven, Belgium, 3000 France CHU de Marseille - Hôpital la Timone Not yet recruiting Marseille, France, 13385 CHU de Bordeaux - Hôpital Haut Lévêque Not yet recruiting Pessac, France, 33604 Germany Universitaetsklinikum Essen Not yet recruiting Essen, Germany, 45122 Switzerland University Hospital Basel Not yet recruiting Basel, Switzerland, CH-4031 United Kingdom Royal Marsden Hospital - Surrey Not yet recruiting Sutton, United Kingdom, SM2 5PT Collapse << |
NCT00845702 | Renal Artery Stenosis | Phase 3 | Terminated(lack of recruitment... more >>.) Collapse << | - | United States, Indiana ... more >> Guerbet LLC Bloomington, Indiana, United States, 47403 Collapse << |
NCT01510561 | Metastatic Pancreatic Adenocar... more >>cinoma Pancreatic Cancer Metastatic Pancreatic Cancer Collapse << | Phase 1 | Unknown | September 2015 | - |
NCT00845702 | - | - | Terminated(lack of recruitment... more >>.) Collapse << | - | - |
NCT03057561 | Coronary Artery Disease ... more >> Cardiomyopathy Collapse << | Not Applicable | Enrolling by invitation | September 30, 2018 | - |
NCT02609919 | - | - | Recruiting | October 2019 | United States, Missouri ... more >> Saint Louis University Recruiting Saint Louis, Missouri, United States, 63110 Contact: Shannon L Farmakis, MD 314-678-5144 farmakis@slu.edu Contact: Shannon Farmakis, MD 314-678-5144 farmakis@slu.edu Principal Investigator: Shannon Farmakis, MD Collapse << |
NCT02213029 | Embryo Transfer | Phase 1 | Terminated | - | United States, California ... more >> GSK Investigational Site Glendale, California, United States, 91206 United States, Maryland GSK Investigational Site Baltimore, Maryland, United States, 21225 Collapse << |
NCT01211873 | Diagnostic Self Evaluation ... more >> Central Nervous System Diseases Collapse << | Phase 3 | Completed | - | - |
NCT03337594 | - | - | Recruiting | October 2019 | United States, South Carolina ... more >> Medical University of South Carolina Recruiting Charleston, South Carolina, United States, 29425 Contact: Elizabeth C O'Quinn, B.S. 843-792-5578 oquinne@musc.edu Contact: Corie L Lynn, B.S. (843)792-8874 lynnc@musc.edu Principal Investigator: Donna R Roberts, M.D. Collapse << |
NCT03730051 | Breast Diseases | Phase 4 | Not yet recruiting | January 2021 | United States, Massachusetts ... more >> Boston Medical Center Not yet recruiting Boston, Massachusetts, United States, 02118 Contact: Nicolas Bloch, MD 617-414-8163 nicolas.bloch@bmc.org Collapse << |
NCT02899377 | Autoimmune Diseases | Phase 1 | Completed | - | United Kingdom ... more >> GSK Investigational Site Cambridge, United Kingdom, CB2 0GG GSK Investigational Site Cambridge, United Kingdom, CB2 0QQ GSK Investigational Site London, United Kingdom, E1 4DG GSK Investigational Site London, United Kingdom, NW1 2PG GSK Investigational Site London, United Kingdom Collapse << |
NCT01101581 | Non Hodgkin's Lymphoma ... more >> NHL Aggressive NHL Diffuse Large B-cell Lymphoma Collapse << | Phase 1 Phase 2 | Unknown | March 2017 | United States, Delaware ... more >> Helen F. Graham Cancer Center Newark, Delaware, United States, 19713 United States, Florida MDACC Orlando Orlando, Florida, United States, 32806 Moffitt Cancer Center Tampa, Florida, United States, 33612 United States, Indiana Goshen Center for Cancer Care Goshen, Indiana, United States, 46526 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, New York Weill Med College of Cornell Univ/NYH New York, New York, United States, 10021 United States, Pennsylvania University of Pennsylvania Cancer Center Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT02973633 | Heart Failure ... more >> Myocardial Infarction Left Ventricular Hypertrophy Collapse << | Early Phase 1 | Recruiting | December 2020 | United States, Massachusetts ... more >> Massachusetts General Hospital Recruiting Charlestown, Massachusetts, United States, 02129 Collapse << |
NCT02431598 | - | - | Completed | - | - |
NCT02592707 | Neuroendocrine Tumors | Phase 1 Phase 2 | Recruiting | May 2022 | Australia ... more >> Peter MacCallum Cancer Centre, Molecular Imaging and Targeted Therapeutics Laboratory Recruiting East Melbourne, Australia, 3002 Ramsay Hollywood Private Hospital, Department of Nuclear Medicine Recruiting Perth, Australia, 6009 Austria University Hospital Vienna, Department of Nuclear Medicine Recruiting Vienna, Austria, 1090 Denmark University Hospital Aarhus, Department of Hepatology and Gastroenterology Recruiting Aarhus, Denmark, 8000 France CHU de Nantes, Hotel Dieu, Service de Medecine Nucleaire Not yet recruiting Nantes, France, 44093 Institut Universitaire Cancer Toulouse Oncopole, Department of Nuclear Medicine Not yet recruiting Toulouse, France, 31059 Switzerland University Hospital Basel, Department of Nuclear Medicine Recruiting Basel, Switzerland, 4031 United Kingdom Royal Free Hospital, Department of Nuclear Medicine Recruiting London, United Kingdom, NW3 2QG Collapse << |
NCT02431598 | Transient Severe Arterial Phas... more >>e Motion Collapse << | Phase 4 | Completed | - | United States, North Carolina ... more >> Duke Medical Center Durham, North Carolina, United States, 27710 Collapse << |
NCT03602339 | Magnetic Resonance Imaging | Phase 4 | Recruiting | November 1, 2019 | - |
NCT01211873 | - | - | Completed | - | - |
NCT03091803 | Intracranial Neoplasm | Not Applicable | Recruiting | April 4, 2021 | United States, California ... more >> USC / Norris Comprehensive Cancer Center Recruiting Los Angeles, California, United States, 90033 Contact: Alexander Lerner 323-865-9914 lernera@med.usc.edu Principal Investigator: Alexander Lerner Collapse << |
NCT00554632 | Venous Thrombosis | Not Applicable | Completed | - | - |
NCT01147393 | Follicular Lymphoma | Phase 1 Phase 2 | Terminated(closed to enrollmen... more >>t due to slow patient accrual) Collapse << | - | United States, New York ... more >> Weill Cornell Medical College New York, New York, United States, 10065 Collapse << |
NCT01729169 | - | - | Completed | - | Denmark ... more >> Aarhus University Hospital Aarhus, Denmark, 8000 Collapse << |
NCT00142415 | Metastatic Renal Cell Carcinom... more >>a Collapse << | Phase 1 Phase 2 | Completed | - | Netherlands ... more >> University Medical Center Nijmegen Nijmegen, Netherlands, 6500HB Collapse << |
NCT00745901 | Contraception | Phase 4 | Completed | - | - |
NCT00142415 | - | - | Completed | - | - |
NCT00745901 | - | - | Completed | - | - |
NCT02080468 | Healthy | Phase 1 | Completed | - | United States, Texas ... more >> Covance Clinical Research Unit, Inc Dallas, Texas, United States, 75247 Collapse << |
NCT00320567 | Osteoporosis | Phase 2 | Completed | - | - |
NCT00439972 | Contraception | Phase 2 | Unknown | December 2011 | United States, Washington ... more >> University of Washington, Northwest Lipid Research Clinic Seattle, Washington, United States, 98104 Collapse << |
NCT03042312 | Metastatic Castration Resistan... more >>t Prostate Cancer Collapse << | Phase 2 | Active, not recruiting | April 11, 2019 | United States, California ... more >> David Geffen School of Medicine at UCLA Los Angeles, California, United States, 90095 United States, Texas Excel Diagnostics and Nuclear Oncology Center Houston, Texas, United States, 77042 Collapse << |
NCT02127593 | Healthy | Phase 1 | Completed | - | Netherlands ... more >> Groningen, Netherlands Collapse << |
NCT00344383 | Metrorrhagia | Phase 2 | Completed | - | - |
NCT00709332 | Drug Interactions ... more >> Contraception Pharmacokinetics Collapse << | Phase 1 | Completed | - | - |
NCT02144246 | Cystic Fibrosis Exacerbations ... more >>While on and Off Hormonal Contraception Collapse << | Phase 1 | Terminated | - | United States, Pennsylvania ... more >> Hospital of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT01475513 | Insulin Sensitivity ... more >> Cardiovascular Risk Perimenopausal Disorder Collapse << | Phase 4 | Completed | - | United States, Virginia ... more >> Virginia Commonwealth University Medical Center Richmond, Virginia, United States, 23298-0111 Collapse << |
NCT00635570 | Birth Control Compliance | Phase 4 | Completed | - | United States, Illinois ... more >> University of Chicago, Section of Family Planning Chicago, Illinois, United States, 60637 University of Chicago Chicago, Illinois, United States, 60637 University of Illinois Chicago, Illinois, United States Collapse << |
NCT01475513 | - | - | Completed | - | - |
NCT00709982 | Drug Interactions ... more >> Healthy Pharmacokinetics Collapse << | Phase 1 | Completed | - | - |
NCT00399685 | HIV Infections | Phase 1 | Completed | - | United States, California ... more >> Covance Clinical Research Unit San Diego San Diego, California, United States, 92123 United States, Washington Northwest Kinetics Tacoma, Washington, United States, 98418 Collapse << |
NCT01373931 | Depressive Disorder, Major | Phase 1 | Completed | - | United States, Wisconsin ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Madison, Wisconsin, United States Collapse << |
NCT00635570 | - | - | Completed | - | - |
NCT01147393 | - | - | Terminated(closed to enrollmen... more >>t due to slow patient accrual) Collapse << | - | - |
NCT02494609 | Healthy | Phase 1 | Unknown | - | United States, Indiana ... more >> Lexicon Investigational Site Evansville, Indiana, United States, 47710 United States, Texas Lexicon Investigational Site Dallas, Texas, United States, 75247 Collapse << |
NCT00205504 | Metabolic Syndrome X ... more >> Insulin Resistance Obesity Cardiovascular Diseases Collapse << | Phase 4 | Completed | - | United States, Virginia ... more >> Virginia Commonwealth University General Clinical Research Center Richmond, Virginia, United States, 23298 Collapse << |
NCT00357604 | HIV Infections | Phase 1 | Completed | - | United States, California ... more >> Covance Cpu, Inc San Diego, California, United States, 92123 Collapse << |
NCT02157467 | Infection, Human Immunodeficie... more >>ncy Virus Collapse << | Phase 1 | Completed | - | - |
NCT00205504 | - | - | Completed | - | - |
NCT00549666 | Pharmacokinetics | Phase 1 | Completed | - | United States, California ... more >> Covance Global Clinical Pharmacology, Inc. San Diego, California, United States, 92123 Collapse << |
NCT01373931 | - | - | Completed | - | - |
NCT01243580 | - | - | Completed | - | - |
NCT01746732 | Healthy Volunteers | Phase 1 | Completed | - | United States, Texas ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Dallas, Texas, United States, 75247 Collapse << |
NCT02533427 | HCV Infection | Phase 1 | Completed | - | New Zealand ... more >> Christchurch, New Zealand Collapse << |
NCT01498861 | Infection, Human Immunodeficie... more >>ncy Virus Collapse << | Phase 1 | Completed | - | United States, Florida ... more >> GSK Investigational Site Miami, Florida, United States, 33169 Collapse << |
NCT00901290 | Pharmacokinetics | Phase 1 | Suspended(suspended pending da... more >>ta analysis) Collapse << | September 2009 | United States, Kansas ... more >> Research Site Overland Park, Kansas, United States Collapse << |
NCT01458210 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | United States, Texas ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Dallas, Texas, United States Collapse << |
NCT01458210 | - | - | Completed | - | - |
NCT01746732 | - | - | Completed | - | - |
NCT01243580 | Healthy | Phase 1 | Completed | - | United States, Florida ... more >> Miami, Florida, United States, 33169 Collapse << |
NCT00983957 | Chronic Hepatitis C | Phase 1 | Completed | - | United States, Arizona ... more >> MDS Pharma Services (US), Inc Tempe, Arizona, United States, 85283 United States, Texas Covance Clinical Research Unit, Inc. Austin, Texas, United States, 78752 Canada, Quebec Local Institution St. Laurent, Quebec, Canada, H4R2N6 Collapse << |
NCT00754065 | Contraception | Phase 3 | Completed | - | - |
NCT00983957 | - | - | Completed | - | - |
NCT00754065 | - | - | Completed | - | - |
NCT01063023 | Hepatitis C Virus | Phase 1 | Completed | - | United States, Kansas ... more >> Pra International Lenexa, Kansas, United States, 66219 Collapse << |
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