生物活性

• 描述Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT01508507	-	-	Unknown	March 2014	India ... more >> Regional Medical Research Center Recruiting Chandrashekharpur, Bhubaneswar, Odisha, India, 751016 Contact: Shantanu K Kar, MD    91-674-301322    rmrcdir@sancharnet.in    Contact: Anna S Kerketta, MBBS    91-674-2301387    solani_bara@rediffmail.com    Sub-Investigator: Hemant K Khuntia, MBBS Collapse <<
  NCT02099240	Osteomyelitis	Early Phase 1	Recruiting	September 2019	United States, Kentucky ... more >> University of Louisville Recruiting Louisville, Kentucky, United States, 40202 Contact: Julio A Ramirez, MD    502-852-1148    jarami01@louisville.edu    Contact: David Seligson, MD    502-852-0923    d0seli01@louisville.edu    Sub-Investigator: Forest Arnold, DO          Sub-Investigator: Timothy Wiemkwn, PhD          Sub-Investigator: Robert Kelley, PhD          Sub-Investigator: James Summersgill, PhD          Sub-Investigator: Ruth Carrico, PhD          Sub-Investigator: Julie Harting, PharmD          Sub-Investigator: Paula Peyrani, MD          Principal Investigator: David Seligson, MD          Sub-Investigator: Craig Roberts, MD          Principal Investigator: Julio Ramirez, MD Collapse <<
  NCT00701792	Cirrhosis	Not Applicable	Completed	-	France ... more >> service d'hépatologie CHU jean Minjoz Besancon, France, 25000 CHRU CAEN - Service d'hépato-gastroentérologie Caen, France, 14033 Hôpital Beaujon - Hépato-gastroentérologie Clichy, France, 92110 CHU Henri Mondor - Hépato-gastroentérologie Creteil, France, 94010 Hépato-gastroenterologie CHU Bocage Dijon, France, 21034 Centre d'épidémiologie de population EPI 106 Dijon, France, 21079 Hôpital Bon secours - Hépato-gastroentérologie Metz, France, 57000 Hôpital Saint-Eloi - Hépato-gastroentérologie Montpellier, France, 34295 Hôpital Pitié-Salpétrière - Hépato-gastroentérologie Paris, France, 75013 Hepato-gastroenterologie Poitiers, France, 86021 CHU Reims - hépato-gestroentérologie Reims, France, 51092 Clinique des maladies du foie Hôpital Pontchailloux Rennes, France, 35000 Hôpital Purpan - Hépato-gastroentérologie Toulouse, France, 31059 Collapse <<

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• 参考文献

• [1] Dong J, Ruan J, et al. In vitro synergistic effects of fisetin and norfloxacin against aquatic isolates of Serratia marcescens. FEMS Microbiol Lett. 2016 Jan;363(1):fnv220.

  [2] Gadebusch HH, Shungu DL, et al. Comparison of the antibacterial activity of norfloxacin (MK 0366, AM 715), a new organic acid, with that of other orally absorbed chemotherapeutic agents. Infection. 1982 Jan;10(1):41-4.