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CAS No.: 18883-66-4
Synonyms: Streptozotocin;U 9889;NSC 85998
Streptozocin is a potent DNA alkylator with antitumor effects, also used to induce diabete model.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01362530 | Chemotherapy Induced Nausea an... more >>d Vomiting Collapse << | Phase 3 | Completed | - | - |
NCT01362530 | - | - | Completed | - | - |
NCT00003543 | Colorectal Cancer | Phase 1 | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Collapse << |
实验方案
技术信息
CAS号 | 18883-66-4 | 储存条件 |
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分子式 | C8H15N3O7 | 运输 | 蓝冰 | |||||||
分子量 | 265.22 | 别名 | Streptozotocin;U 9889;NSC 85998;STZ;Estreptozocin;NSC 37917;NCI-C03167;AI3-50821;NRRL 2697;SZC;SZN;streptozotocin. US brand name: Zanosar;链脲佐菌素 | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01362530 | Chemotherapy Induced Nausea an... more >>d Vomiting Collapse << | Phase 3 | Completed | - | - |
NCT01362530 | - | - | Completed | - | - |
NCT00003543 | Colorectal Cancer | Phase 1 | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Collapse << |
NCT01709123 | Diabetes Mellitus, Type 1 | Not Applicable | Unknown | September 2013 | United States, Louisiana ... more >> Louisiana State University Health Sciences Center in Shreveport Recruiting Shreveport, Louisiana, United States, 71130 Contact: Sushil K Jain, Ph.D. 318-675-6086 sjain@lsuhsc.edu Sub-Investigator: Robert McVie, M.D. Sub-Investigator: Tommie Stapleton, RN, CCRC Sub-Investigator: Cynthia Brewer, RN Sub-Investigator: John Rowell, RN, MSN Sub-Investigator: Henry R McKnight, RPH Sub-Investigator: Pat F Bass, M.D. Sub-Investigator: Shikha Mane, M.D. Sub-Investigator: David Micinski, BS Sub-Investigator: Neslihan Gungor, M.D. Collapse << |
NCT03758014 | GBM | Phase 2 Phase 3 | Recruiting | April 30, 2021 | China, Beijing ... more >> Beijing Tiantan Hospital, Capital Medical University Recruiting Beijing, Beijing, China Contact: Wenbin Li Collapse << |
NCT00448136 | Neoplasms | Phase 2 | Completed | - | France ... more >> Angers, France, 49933 Bordeaux, France, 33075 Boulogne Billancourt, France, 92104 Caen, France, 14033 Chambray Les Tours, France, 37171 Clichy, France, 92118 Creteil, France, 94010 Dijon, France, 21079 Lille, France, 59020 Lyon, France, 69437 Marseille, France, 13273 Marseille, France, 13285 Marseille, France, 13385 Montpellier, France, 34298 Nantes, France, 44093 Nice, France, 06189 Paris, France, 75571 Paris, France, 75651 Paris, France, 75908 Paris, France, 75970 Poitiers, France, 86021 Reims, France, 51092 Rouen, France, 76031 Saint Brieuc, France, 22015 Strasbourg, France, 67091 Toulouse, France, 31059 Villejuif, France, 94805 Collapse << |
NCT03217097 | Neuroendocrine Tumors | Phase 4 | Not yet recruiting | October 2021 | France ... more >> Hôpital Sud - CHU Amiens Not yet recruiting Amiens, France, 80054 Contact: Vincent HAUTEFEUILLE, MD Principal Investigator: Vincent HAUTEFEUILLE, MD CHU d'Angers Not yet recruiting Angers, France, 49933 Contact: Sandrine LABOUREAU, MD Principal Investigator: Sandrine LABOUREAU, MD Hôpital Beaujon - APHP Not yet recruiting Clichy, France, 92118 Contact: Olivia HENTIC, MD Principal Investigator: Olivia HENTIC, MD Hôpital François Mitterrand - CHU Dijon Bourgogne Not yet recruiting Dijon, France, 21000 Contact: Côme LEPAGE, MD Principal Investigator: Côme LEPAGE, MD Hôpital André Michalon - CHU Grenoble Alpes Not yet recruiting La Tronche, France, 38700 Contact: Victoire GRANGER, MD Principal Investigator: Victoire GRANGER, MD Centre Oscar Lambret Not yet recruiting Lille, France, 59020 Contact: Eric DANSIN, MD Principal Investigator: Eric DANSIN, MD Hôpital Claude Hurriet - CHRU Lille Not yet recruiting Lille, France, 59037 Contact: Christine DO CAO, MD Principal Investigator: Christine DO CAO, MD Hôpital Edouard Herriot - Hospices Civils de Lyon Not yet recruiting Lyon, France, 69003 Contact: Thomas WALTER, MD Principal Investigator: Catherine LOMBARD BOHAS, MD Sub-Investigator: Thomas WALTER, MD Hôpital Privé Jean Mermoz Not yet recruiting Lyon, France, 69008 Contact: Jérôme DESRAMES, MD Principal Investigator: Jérôme DESRAMES, MD Centre Léon Bérard Not yet recruiting Lyon, France, 69373 Contact: Matthieu SARABI, MD Principal Investigator: Matthieu SARABI, MD Institut Paoli Calmettes Not yet recruiting Marseille, France, 13009 Contact: Patricia NICCOLI, MD Principal Investigator: Patricia NICCOLI, MD Hôpital Saint Eloi - CHU Montpellier Not yet recruiting Montpellier, France, 34090 Contact: Eric ASSENAT, MD Principal Investigator: Eric ASSENAT, MD Hôpital Saint Louis - APHP Not yet recruiting Paris, France, 75010 Contact: Thomas APARICIO, MD Principal Investigator: Thomas APARICIO, MD Hôpital Cochin - APHP Not yet recruiting Paris, France, 75014 Contact: Romain CORIAT, MD Principal Investigator: Romain CORIAT, MD CH Annecy Genevois Not yet recruiting Pringy, France, 74374 Contact: Mathieu BACONNIER, MD Principal Investigator: Mathieu BACONNIER, MD Hôpital Robert Debré - CHU Reims Not yet recruiting Reims, France, 51092 Contact: Guillaume CADIOT, MD Principal Investigator: Guillaume CADIOT, MD Hôpital Nord - CHU Saint Etienne Not yet recruiting Saint-Priest-en-Jarez, France, 42270 Contact: Nicolas WILLIET, MD Principal Investigator: Nicolas WILLIET, MD Institut de Cancérologie de la Loire Not yet recruiting Saint-Priest-en-Jarez, France, 42270 Contact: Léa SABAN-ROCHE, MD Principal Investigator: Léa SABAN-ROCHE, MD Hôpital Rangueil - CHU Toulouse Not yet recruiting Toulouse, France, 31059 Contact: Rosine GUIMBAUD, MD Principal Investigator: Rosine GUIMBAUD, MD Hôpital Trousseau - CHU Tours Not yet recruiting Tours, France, 37044 Contact: Thierry LECOMTE, MD Principal Investigator: Thierry LECOMTE, MD Institut Gustave Roussy Not yet recruiting Villejuif, France, 94805 Contact: Eric BAUDIN, MD Principal Investigator: Eric BAUDIN, MD Collapse << |
NCT00633763 | - | - | Completed | - | United States, California ... more >> University of California Irvine Medical Center Orange, California, United States, 92868 Collapse << |
NCT02246127 | Neuroendocrine Tumors | Phase 3 | Recruiting | June 2020 | - |
NCT00094497 | Carcinoma, Adrenal Cortical | Phase 3 | Completed | - | United States, Maryland ... more >> National Cancer Institute - Center for Cancer Research Bethesda, Maryland, United States United States, Michigan University of Michigan, Department of Internal Medicine Ann Arbor, Michigan, United States, 48109 Australia Royal Adelaide Hospital Adelaide, Australia, SA 5000 Austria University of Graz Graz, Austria, 8036 France Clinique Marc Linquette Lille, France Centre Leon Berard Lyon, France Hospital de Marseille la timone Marseille, France, 13385 Cochin Hospital Paris, France, 75679 Hospital Bordeaux haut leveque Pessac, France, 33600 Institut Gustave Roussy Villejuif, France, 94805 Germany Charité-University, Dept. of Endocrinology; Campus Benjamin Franklin Berlin, Germany Charité-Universitätsmedizin Berlin - Campus Mitte Berlin, Germany Dept. of Medicine III Dresden, Germany University of Duesseldorf, Dept. of Endocrrinology Duesseldorf, Germany, 40001 Zentrum für Innere Medizin - Endokrinologie des Universitätsklinikum Essen Essen, Germany Endokrinologie Medizinische Hochschule Hannover Hannover, Germany Otto-von-Guericke University; Dept. of Endocrinology Magdeburg, Germany, 39120 Dept of Medicine I Mainz, Germany University of Munich, Dept. of Internal Medicine (Innenstadt) Munich, Germany, 80336 University of Wuerzburg - Dept. of Medicine Wuerzburg, Germany, 97080 Italy University of Turin, Dept of Internal Medicine Orbassano, Italy, 10043 Clinica Endocrinologica, Università di Padova, Azienda Ospedaliera di Padova Padova, Italy Netherlands Vrije Universiteit Medisch Centrum Amsterdam, Netherlands, 1007 Academisch Medisch Centrum; Dept. of Endocrinology Amsterdam, Netherlands, 1105 AZ Maxima Medisch Centrum; Dept. of Internal Medicine Eindhoven, Netherlands, 5631 BM University Hospital Groningen; Dept. of Internal Medine Groningen, Netherlands, 9700 Leiden University Medical Center Leiden, Netherlands Sweden Department of Oncology, Sahlgrenska University Hospital Gothenburg, Sweden Department of Oncology, Linköping University Hospital Linköping, Sweden Department of Medicine, The Jubileum Institute, Lund University Lund, Sweden Dept of Surgery, Karolinska Hospital, Stockholm Stockholm, Sweden Uppsala University Hospital - Dept of Medical Sciences Uppsala, Sweden, 751 85 Collapse << |
NCT00094497 | - | - | Completed | - | - |
NCT00001165 | Islet Cell Adenoma ... more >> Neoplasm Metastasis Zollinger Ellison Syndrome Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Bethesda, Maryland, United States, 20892 Collapse << |
NCT03351296 | Pancreatic Cancer | Phase 2 | Not yet recruiting | June 2023 | France ... more >> Gustave Roussy Not yet recruiting Villejuif, Val De Marne, France, 94805 Contact: Michel Ducreux, MD, PhD 0142116017 ext +33 michel.ducreux@gustaveroussy.fr Contact: Dune Lemettre 0142116643 ext +33 dune.lemettre@gustaveroussy.fr Collapse << |
NCT00602082 | Gastrointestinal Carcinoid Tum... more >>or Islet Cell Tumor Collapse << | Phase 2 | Completed | - | United Kingdom ... more >> Basildon University Hospital Basildon, England, United Kingdom, SS16 5NL Addenbrooke's Hospital Cambridge, England, United Kingdom, CB2 2QQ Cookridge Hospital Leeds, England, United Kingdom, LS16 6QB Leicester Royal Infirmary Leicester, England, United Kingdom, LE1 5WW Aintree University Hospital Liverpool, England, United Kingdom, L9 7AL UCL Cancer Institute London, England, United Kingdom, NW3 2QG St. Thomas' Hospital London, England, United Kingdom, SE1 7EH Mid Kent Oncology Centre at Maidstone Hospital Maidstone, England, United Kingdom, ME16 9QQ Christie Hospital Manchester, England, United Kingdom, M20 4BX Clatterbridge Centre for Oncology Merseyside, England, United Kingdom, CH63 4JY Northern Centre for Cancer Treatment at Newcastle General Hospital Newcastle-Upon-Tyne, England, United Kingdom, NE4 6BE Oxford Radcliffe Hospital Oxford, England, United Kingdom, 0X3 9DU Royal Marsden - Surrey Sutton, England, United Kingdom, SM2 5PT Southend University Hospital NHS Foundation Trust Westcliff-On-Sea, England, United Kingdom, SS0 0RY Edinburgh Cancer Centre at Western General Hospital Edinburgh, Scotland, United Kingdom, EH4 2XU Beatson West of Scotland Cancer Centre Glasgow, Scotland, United Kingdom, G12 0YN Velindre Cancer Center at Velindre Hospital Cardiff, Wales, United Kingdom, CF14 2TL Collapse << |
NCT00609765 | Pancreatic Cancer | Phase 2 | Terminated(Development of new ... more >>chemotherapy standard of care for treatment rendered the trial obsolete.) Collapse << | - | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 Collapse << |
NCT00609765 | - | - | Terminated(Development of new ... more >>chemotherapy standard of care for treatment rendered the trial obsolete.) Collapse << | - | - |
NCT00448136 | - | - | Completed | - | - |
NCT00004688 | Anaplastic Astrocytoma ... more >> Anaplastic Oligodendroglioma Mixed Gliomas Glioblastoma Multiforme Recurrent Brain Tumor Collapse << | Phase 2 | Completed | - | - |
NCT03612232 | Adrenocortical Carcinoma | Phase 2 | Not yet recruiting | June 2022 | Germany ... more >> University Hospital Würzburg Not yet recruiting Würzburg, Germany, 97080 Contact: Matthias Kroiss, MD, PhD +4993120139740 Kroiss_M@ukw.de Contact: Martin Fassnacht, MD +4993120139200 Fassnacht_M@ukw.de Collapse << |
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