CAS No.: 1449-05-4
18α-Glycyrrhetinic acid/18-α-甘草次酸 Catalog No. CSN17219
Synonyms: 18alpha-Glycyrrhetinic Acid;18-α-甘草次酸
18α-Glycyrrhetinic acid has been shown to inhibit connexin-26 (gap junction β-2 protein), a tumor suppressor gene expressed in HeLa cells.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Mahmoud AM, Hussein OE, et al. Methotrexate hepatotoxicity is associated with oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18β-Glycyrrhetinic acid. Chem Biol Interact. 2017 May 25;270:59-72.
- [2] Piwowarczyk K, Paw M, et al. Connexin43(high) prostate cancer cells induce endothelial connexin43 up-regulation through the activation of intercellular ERK1/2-dependent signaling axis. Eur J Cell Biol. 2017 Apr 1. pii: S0171-9335(16)30299-0.
- [3] Huang YC, Kuo CL, Lu KW, Lin JJ, Yang JL, Wu RS, Wu PP, Chung JG. 18α-Glycyrrhetinic Acid Induces Apoptosis of HL-60 Human Leukemia Cells through Caspases- and Mitochondria-Dependent Signaling Pathways. Molecules. 2016 Jul 1;21(7):872. doi: 10.3390/molecules21070872. PMID: 27376261; PMCID: PMC6273602.
- [4] Papaevgeniou N, Sakellari M, Jha S, Tavernarakis N, Holmberg CI, Gonos ES, Chondrogianni N. 18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures. Antioxid Redox Signal. 2016 Dec 1;25(16):855-869. doi: 10.1089/ars.2015.6494. Epub 2016 Mar 30. PMID: 26886723; PMCID: PMC5124744.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1449-05-4 | 储存条件 |
|
|
| 分子式 | C30H46O4 | 运输 | 蓝冰 | |
| 分子量 | 470.68 | 别名 | 18alpha-Glycyrrhetinic Acid;18-α-甘草次酸 |
