|2,5,7,8-四甲基-2-(4,8,12-三甲基十三烷基)苯并二氢吡喃-6-醇|CsnPharm

CAS No.: 10191-41-0

DL-α-生育酚 Catalog No. CSN25154

Synonyms: DL-α-生育酚;DL-α-Tocopherol

(±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage. It is one of the components in MF59 and AS03 adjuvant.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述(±)-α-Tocopherol is the compound demonstrating the highest vitamin E activity, which is available both in its natural form as RRR-alpha-tocopherol isolated from plant sources^[1]. The alpha-tocopherol transfer protein (TTP) is a critical regulator of vitamin E status that stimulates the movement of vitamin E between membrane vesicles in vitro and facilitates the secretion of tocopherol from hepatocytes^[2]. α-Tocopherol serves as a peroxyl radical scavenger that protects polyunsaturated fatty acids in membranes and lipoproteins. The biological activity of vitamin E is highly dependent upon regulatory mechanisms that serve to retain α-tocopherol and excrete the non-α-tocopherol forms. This preference is dependent upon the combination of the function of α-tocopherol transfer protein (α-TTP) to enrich the plasma with α-tocopherol and the metabolism of non-α-tocopherols^[3]. In patients with Abetalipoproteinemia, tocofersolan and α-tocopherol acetate bioavailabilities were extremely low (2.8% and 3.1%, respectively) ^[4].
参考文献

[1] Jensen SK, Lauridsen C. Alpha-tocopherol stereoisomers. Vitam Horm. 2007;76:281-308
[2] Manor D, Morley S. The alpha-tocopherol transfer protein. Vitam Horm. 2007;76:45-65
[3] Niki E, Traber MG. A history of vitamin E. Ann Nutr Metab. 2012;61(3):207-12
[4] Cuerq C, Henin E, Restier L, Blond E, Drai J, Marçais C, Di Filippo M, Laveille C, Michalski MC, Poinsot P, Caussy C, Sassolas A, Moulin P, Reboul E, Charriere S, Levy E, Lachaux A, Peretti N. Efficacy of two vitamin E formulations in patients with abetalipoproteinemia and chylomicron retention disease. J Lipid Res. 2018 Sep;59(9):1640-1648

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.3218 mL
- 11.6088 mL
- 23.2177 mL
- 5 mM
- 0.4644 mL
- 2.3218 mL
- 4.6435 mL
- 10 mM
- 0.2322 mL
- 1.1609 mL
- 2.3218 mL

技术信息

CAS号	10191-41-0	储存条件	粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C29H50O2	运输	蓝冰
分子量	430.71	别名	DL-α-生育酚;DL-α-Tocopherol

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

DL-α-生育酚 Catalog No. CSN25154

靶点选择性

请登录您的专属账户

确认信息