|2-(3,4-二羟基苯基)-5,7-二羟基-3-(((2S,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-4H-苯并吡喃-4-酮|CsnPharm

CAS No.: 522-12-3

槲皮苷 Catalog No. CSN16618

Synonyms: Quercetin 3-rhamnoside;C.I. 75720;NSC 9221

Quercitrin, a natural product isolated and purified from the herb of Apocynum venetum L.It can be found in a wide range of medicinal plants and has been reported to have antioxidant, antiviral, and anti-inflammatory properties.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Quercitrin, a natural product isolated and purified from the herb of Apocynum venetum L. Quercitrin (50, 100, and 200 mg/kg, p.o.) can maintain the level of mitochondrial complex I in injured cells and restore its activity, which reduces the production of ROS (reactive oxygen species), protects the mitochondria from oxidative stress, and has a protective effect on the liver^[3]. Intra-articular injection of quercitrin increased bone volume/tissue volume of tibial subchondral bone and cartilage thickness and reduced the Osteoarthritis Research Society International scores in OA (osteoarthritis) rats. Meanwhile, immunohistochemical results showed that quercitrin exerted anti-OA effect by delaying ECM (extracellular matrix) degradation^[4]. Quer improves dysregulated lipid metabolism and reduces hepatic steatosis and inflammation by compensating for estrogen deficiency^[5]. In addition, quercitrin exhibited the most antiallergic activity against antigen-induced β-hexosaminidase release and IL-4 mRNA expression, which are markers of degranulation in RBL-2H3 cells. After a 7-sensitizing period, 14 days of DNCB (2,4-dinitrochlorobenzene) treatment with or without topical pimecrolimus (1%) or quercitrin (0.5%) treatment, quercitrin was found to suppress DNCB-induced increases in serum IL-4 and IgE concentrations and transepidermal water loss^[6].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.2303 mL
- 11.1513 mL
- 22.3027 mL
- 5 mM
- 0.4461 mL
- 2.2303 mL
- 4.4605 mL
- 10 mM
- 0.2230 mL
- 1.1151 mL
- 2.2303 mL

技术信息

CAS号

522-12-3

储存条件

粉末: Keep in dark place,Sealed in dry,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C21H20O11

运输

蓝冰

分子量

448.38

别名

Quercetin 3-rhamnoside;C.I. 75720;NSC 9221;Quercetin 3-L-rhamnoside;Thujin;槲皮苷

溶解度

DMSO	255.0 mg/mL (568.7 mM)
Water	insoluble

动物实验配方

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

槲皮苷 Catalog No. CSN16618

靶点选择性

请登录您的专属账户

确认信息