|2-甲基-3-((7R,11R,E)-3,7,11,15-四甲基十六烷-2-烯-1-基)萘-1,4-二酮|CsnPharm

CAS No.: 84-80-0

植物甲萘醌 Catalog No. CSN23541

Synonyms: Phylloquinone;Phytomenadione;NSC 270681

Vitamin K1 a fat-soluble, naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Vitamin K1 a fat-soluble, naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. Vitamin K1 treatment caused a significant antiproliferative effect and induced apoptosis in all the cell lines, with the involvement of the MAPK pathway. A significant polyamine decrease in addition to the antiproliferative and proapoptotic effects following vitamin K1 administration to colon cancer cell lines^[1]. Vitamin K1 strengthens coagulation as measured by PT decrease and increases in the activity of vitamin K-dependent clotting factors and thrombin generation^[2]. Maternal vitamin K supplementation increases milk vitamin K levels and can improve vitamin K status in breastfed infants who receive intramuscular vitamin K shortly after birth^[3].
参考文献

[1] Orlando A, Linsalata M, Tutino V, D'Attoma B, Notarnicola M, Russo F. Vitamin K1 exerts antiproliferative effects and induces apoptosis in three differently graded human colon cancer cell lines. Biomed Res Int. 2015;2015:296721
[2] Dahlberg S, Schött U, Eriksson EÄ, Tahirsylaj Y, Schurgers L, Kander T. Intravenous Vitamin K1 for the Correction of Prolonged Prothrombin Times in Non-Bleeding Critically Ill Patients: A Prospective Observational Study. Nutrients. 2021 Jul 27;13(8):2580
[3] Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. Vitamin K. 2021 Oct 18

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.2188 mL
- 11.0939 mL
- 22.1877 mL
- 5 mM
- 0.4438 mL
- 2.2188 mL
- 4.4375 mL
- 10 mM
- 0.2219 mL
- 1.1094 mL
- 2.2188 mL

技术信息

CAS号

84-80-0

储存条件

粉末: Keep in dark place,Inert atmosphere,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C31H46O2

运输

蓝冰

分子量

450.70

别名

Phylloquinone;Phytomenadione;NSC 270681;ɑ-Phylloquinone;trans-Phylloquinone;VITAMIN K1;3-Phytylmenadione;Alpha-Phylloquinone;Aquamephyton;Konakion;Phyllohydroquinone;叶绿醌;维生素K1

溶解度

DMSO	5.6 mg/mL (12.4 mM)
Ethanol	50.0 mg/mL (110.9 mM)

动物实验配方

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

植物甲萘醌 Catalog No. CSN23541

靶点选择性

请登录您的专属账户

确认信息