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CAS No.: 5234-68-4

萎锈灵 Catalog No. CSN23804

Synonyms: Carboxine;Fenoxan;CCRIS 5217

Carboxin is an fungicide used in agriculture.

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技术信息

生物活性

描述Carboxin (Carboxine) is a systemic agricultural fungicide and seed protectant. Carboxin demonstrates high specificity against the fungal class Basideomycetes, Deuteromycetes and Phycomycetes^[1]. Carboxin is a potent inhibitor of the enzyme of certain organisms. The bacterium Paracoccus denitrificans was found to be sensitive to carboxin in vivo, and mutants that grow in the presence of 3'-methyl carboxin were isolated^[2]. The systemic fungicide carboxin (5,6-dihydro-2-methyl-1,4-oxathiin-3-carboxanilide) inhibited oxidation of succinate by membranes prepared from Micrococcus denitrificans, the K(i) being 16 muM. Carboxin also inhibited dichlorophenol indophenol (DCIP) reductase activities in a manner both qualitatively and quantitatively similar to the inhibition of oxidation of the various substrates^[3].
参考文献

[1] Frampton CS, Frampton ES, Thomson PA. Two polymorphic forms of the oxathiin systemic fungicide active carboxine. Acta Crystallogr E Crystallogr Commun. 2018;74(Pt 12):1741-1745. Published 2018 Nov 9
[2] Matsson M, Ackrell BA, Cochran B, Hederstedt L. Carboxin resistance in Paracoccus denitrificans conferred by a mutation in the membrane-anchor domain of succinate:quinone reductase. Arch Microbiol. 1998 Jul;170(1):27-37
[3] Tucker AN, Lillich TT. Effect of the systemic fungicide carboxin on electron transport function in membranes of Micrococcus denitrificans. Antimicrob Agents Chemother. 1974 Nov;6(5):572-8

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.2499 mL
- 21.2495 mL
- 42.4989 mL
- 5 mM
- 0.8500 mL
- 4.2499 mL
- 8.4998 mL
- 10 mM
- 0.4250 mL
- 2.1249 mL
- 4.2499 mL

技术信息

CAS号

5234-68-4

储存条件

粉末: Sealed in dry,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C12H13NO2S

运输

蓝冰

分子量

235.30

别名

Carboxine;Fenoxan;CCRIS 5217;Cerevax;D-735;萎锈灵;卡波辛

溶解度

DMSO	47.0 mg/mL (199.7 mM)

动物实验配方

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