CAS No.: 66-76-2
双香豆素 Catalog No. CSN12453
Synonyms: Dicumarol;NSC 17860;NSC 41834
Dicoumarolis a widely used potent competitive NQO1 inhibitor.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Bian J, Li X, et al. Affinity-based small fluorescent probe for NAD(P)H:quinone oxidoreductase 1 (NQO1). Design, synthesis and pharmacological evaluation. Eur J Med Chem. 2017 Feb 15;127:828-839.
- [2] Zhang W, Su J, et al. Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells. PLoS One. 2017 Jun 15;12(6):e0179672.
- [3] Bian J, Li X, Xu L, Wang N, Qian X, You Q, Zhang X. Affinity-based small fluorescent probe for NAD(P)H:quinone oxidoreductase 1 (NQO1). Design, synthesis and pharmacological evaluation. Eur J Med Chem. 2017 Feb 15;127:828-839
- [4] Zhang W, Su J, Xu H, Yu S, Liu Y, Zhang Y, Sun L, Yue Y, Zhou X. Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells. PLoS One. 2017 Jun 15;12(6):e0179672
- [5] Qadri SM, Kucherenko Y, Zelenak C, Jilani K, Lang E, Lang F. Dicoumarol activates Ca2+-permeable cation channels triggering erythrocyte cell membrane scrambling. Cell Physiol Biochem. 2011;28(5):857-64
- [6] Jing YW, Yi J, Chen YY, Hu QS, Shi GY, Li H, Tang XM. Dicoumarol alters cellular redox state and inhibits nuclear factor kappa B to enhance arsenic trioxide-induced apoptosis. Acta Biochim Biophys Sin (Shanghai). 2004 Mar;36(3):235-42
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 66-76-2 | 储存条件 |
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| 分子式 | C19H12O6 | 运输 | 蓝冰 | |||||||||||||
| 分子量 | 336.30 | 别名 | Dicumarol;NSC 17860;NSC 41834;NSC 221570;Bishydroxycoumarin;Dicoumarin;Melitoxin;Antitrombosin;双香豆素 | |||||||||||||
| 溶解度 |
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动物实验配方 |
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