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CAS No.: 41100-52-1

盐酸美金刚 Catalog No. CSN16342

Synonyms: Memantine (hydrochloride);Akatinol;Axura

Memantine HCl, an amantadine derivative with low to moderate-affinity for NMDA receptors, inhibit CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively, is used for the treatment of Alzheimer's disease.

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  • 描述
  • 临床研究
  • NCT号适应症或疾病临床期招募状态预计完成时间地点
    NCT03043001AOD Effects and ConsequencesPhase 3Enrolling by invitationDecember 31, 2017Taiwan ... more >> National Cheng Kung University Hospital Tainan, Taiwan, 704 Collapse <<
    NCT00646204Parkinson's DiseasePhase 4Completed-United States, Texas ... more >> PDCMDC 6550 Fannin, Suite 1801 Houston, Texas, United States, 77030 Collapse <<
    NCT01261741Memory Disorder ... more >> Retention Disorder, Cognitive Subjective Cognitive Impairment Memory, Concentration or Attention Problems Collapse <<Phase 2Completed-Germany ... more >> Universitätsklinikum der RWTH Aachen Aachen, Germany, 52074 Klinische Forschung Berlin-Mitte Berlin-Mitte, Germany, 10117 Praxis Dr. Heidenreich Böblingen, Germany, 71032 Universitätsklinikum Carl Gustav Carus Dresden, Germany, 01307 Praxis Dr. Albrecht Ellwangen, Germany, 73479 Praxis Dr. Reifschneider Erbach, Germany, 64711 Klinische Forschung Hannover-Mitte Hannover, Germany, 30159 ZSL Zentrum für medizinische Studien in Leipzig Leipzig, Germany, 04157 Praxis Dr. Pauls München, Germany, 80331 Praxis Dr. Kühn Oranienburg, Germany, 16515 Praxis Dr. Krause Wolfratshausen, Germany, 82515 United Kingdom Royal United Hospital Bath, United Kingdom, BA1 3NG Community Pharmacology Services (CPS) Glasgow, United Kingdom, G20 0XA Moorgreen Hospital West End, Southampton, United Kingdom, SO30 3JB Collapse <<
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  • 参考文献

实验方案

技术信息

CAS号 41100-52-1 储存条件
分子式 C12H22ClN 运输 蓝冰
分子量 215.76 别名 Memantine (hydrochloride);Akatinol;Axura;Ebix;Namenda;NSC 102290;SUN Y7017;D-145 HCl;Memantine Hydrochloride;Memantine HCl;D-145;Ebixa;Ebixza;盐酸美金刚;D-145 hydrochloride
溶解度
DMSO43.0 mg/mL (199.3 mM)
Water29.0 mg/mL (134.4 mM)
Ethanol42.0 mg/mL (194.7 mM)
动物实验配方

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