|3,7,7-三甲基双环[4.1.0]庚-3-烯|CsnPharm

CAS No.: 13466-78-9

Synonyms: Carene;Delta-3-Carene;3-蒈烯

3-Carene is a bicyclic monoterpene which occurs naturally as a constituent of turpentine.

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400-920-2911

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描述3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation. The stimulatory effect of 3-carene on mineralization might be associated with its potential to induce the protein expression/activation of the mitogen-activated protein kinases and the transcript levels of osteoblast mineralization-related genes such as osteopontin and type I collagen^[3]. Oral administration of 3-carene increases the sleep duration and reduces sleep latency in pentobarbital- induced sleep test. 3-Carene potentiates the GABAA receptor-mediated synaptic responses by prolonging the decay time constant of inhibitory synaptic responses^[4]. 3-carene had strong antibacterial activity against B. thermosphacta and P. fluorescens via membrane damage, bacterial metabolic perturbations, and genomic DNA structure disruption, interfering in cellular functions and even causing cell death^[5].
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技术信息

CAS号	13466-78-9	储存条件	粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6 月 -80°C:12月
分子式	C10H16	运输	蓝冰
分子量	136.23	别名	Carene;Delta-3-Carene;3-蒈烯

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