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CAS No.: 86347-15-1

盐酸美托咪定 Catalog No. CSN16498

Synonyms: MPV785;Medetomidine HCl;Precedex. Domitor. Selektope

Medetomidine HCl is an α2 adrenergic agonist used as both a surgical anesthetic and analgesic.

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技术信息

生物活性

描述Medetomidine hydrochloride is a highly selective alpha-2 agonist, which has sedative, anxiolytic, muscle relaxant, and analgesic properties. Medetomidine has a selectivity ratio of 1620/1 (α2/α1), which is 5–10 times higher than that for detomidine (260/1) and xylazine (160/1). Earlier studies of medetomidine in clinical practice suggested the optimal dose to be 30–40 μg/kg BW (bodyweight) for dogs. The highest dose of medetomidine recommended for dogs is 80 μg/kg BW^[3]. IM administration of medetomidine or xylazine to dogs reduced tear flow in a dose-related manner^[4]. Recovery from hypoinsulinemia induced by the medetomidine–midazolam combination tended to be more rapid than when the same dose of medetomidine was used alone^[5].
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01524367	Agitation	Phase 4	Completed	-	Korea, Republic of ... more >> Gangnam severance hospital Seoul, Korea, Republic of Collapse <<

参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.2240 mL
- 21.1202 mL
- 42.2403 mL
- 5 mM
- 0.8448 mL
- 4.2240 mL
- 8.4481 mL
- 10 mM
- 0.4224 mL
- 2.1120 mL
- 4.2240 mL

技术信息

CAS号

86347-15-1

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C13H17ClN2

运输

蓝冰

分子量

236.74

别名

MPV785;Medetomidine HCl;Precedex. Domitor. Selektope;盐酸美托咪定

溶解度

DMSO	12.0 mg/mL (50.7 mM)
Ethanol	47.0 mg/mL (198.5 mM)

动物实验配方

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