CAS No.: 1134-47-0
巴氯芬 Catalog No. CSN10524
Synonyms: (±)-Baclofen;(RS)-Baclofen;Lioresal
Baclofen, a gamma-amino-butyric acid derivative, is a selective GABAB agonist with IC50 of 200 nM which used as a skeletal muscle relaxant.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00814632 Vulvodynia Phase 2 Completed - United States, Michigan ... more >> William Beaumont Hospital Royal Oak, Michigan, United States, 48073 Collapse << NCT01244113 Cerebral Palsy Not Applicable Completed - Korea, Republic of ... more >> Severance Hospital Seoul, Korea, Republic of, 120-752 Collapse << NCT02771925 Alcohol Dependence Phase 4 Unknown May 2018 India ... more >> Dyanand Medical College and Hospital Recruiting Ludhiana, Punjab, India, 141001 Contact: Sandeep Singh Sidhu, MD,DM +919814025085 sandeepsidhu1963@gmail.com Contact: Omesh Goyal, MD,DM +919914821155 goyalomesh@yahoo.co.in Principal Investigator: Sandeep Singh Sidhu, MD,DM Collapse << - 更多
- 参考文献
- [1] Bexis S, Phillis BD, et al. Baclofen prevents MDMA-induced rise in core body temperature in rats. Drug Alcohol Depend. 2004 Apr 9;74(1):89-96.
- [2] Perry HE, Wright RO, et al. Baclofen overdose: drug experimentation in a group of adolescents. Pediatrics. 1998 Jun;101(6):1045-8.
- [3] Farokhnia M, Deschaine SL, Sadighi A, Farinelli LA, Lee MR, Akhlaghi F, Leggio L. A deeper insight into how GABA-B receptor agonism via baclofen may affect alcohol seeking and consumption: lessons learned from a human laboratory investigation. Mol Psychiatry. 2021 Feb;26(2):545-555
- [4] Lake W, Shah H. Intrathecal Baclofen Infusion for the Treatment of Movement Disorders. Neurosurg Clin N Am. 2019 Apr;30(2):203-209
- [5] Bexis S, Phillis BD, Ong J, White JM, Irvine RJ. Baclofen prevents MDMA-induced rise in core body temperature in rats. Drug Alcohol Depend. 2004 Apr 9;74(1):89-96
- [6] Chartier M, Tannous S, Benturquia N, Labat L, Reis R, Risède P, Chevillard L, Mégarbane B. Baclofen-Induced Neuro-Respiratory Toxicity in the Rat: Contribution of Tolerance and Characterization of Withdrawal Syndrome. Toxicol Sci. 2018 Jul 1;164(1):153-165
- [7] Logge WB, Baillie AJ, Haber PS, Morley KC. Baclofen modulates cardiovascular responses to appetitive cues in treatment-seeking alcohol use disorder individuals. Hum Psychopharmacol. 2020 Mar;35(2):e2722
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1134-47-0 | 储存条件 |
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| 分子式 | C10H12ClNO2 | 运输 | 蓝冰 | |||
| 分子量 | 213.66 | 别名 | (±)-Baclofen;(RS)-Baclofen;Lioresal;Liofen;Gablofen;Baclon;Kemstro;巴氯芬 | |||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT00814632 | Vulvodynia | Phase 2 | Completed | - | United States, Michigan ... more >> William Beaumont Hospital Royal Oak, Michigan, United States, 48073 Collapse << |
| NCT01244113 | Cerebral Palsy | Not Applicable | Completed | - | Korea, Republic of ... more >> Severance Hospital Seoul, Korea, Republic of, 120-752 Collapse << |
| NCT02771925 | Alcohol Dependence | Phase 4 | Unknown | May 2018 | India ... more >> Dyanand Medical College and Hospital Recruiting Ludhiana, Punjab, India, 141001 Contact: Sandeep Singh Sidhu, MD,DM +919814025085 sandeepsidhu1963@gmail.com Contact: Omesh Goyal, MD,DM +919914821155 goyalomesh@yahoo.co.in Principal Investigator: Sandeep Singh Sidhu, MD,DM Collapse << |
| NCT00814632 | - | - | Completed | - | - |
| NCT01457352 | Spasticity | Phase 3 | Active, not recruiting | March 2018 | - |
| NCT03682978 | Autism Spectrum Disorder | Phase 2 | Not yet recruiting | January 31, 2021 | - |
| NCT01325220 | Fragile X Syndrome | Phase 3 | Completed | - | - |
| NCT03347240 | Secondary Dystonia | Not Applicable | Completed | - | - |
| NCT01288716 | Autism Spectrum Disorders | Phase 2 | Completed | - | - |
| NCT01797185 | Spasticity | Phase 3 | Active, not recruiting | March 2018 | - |
| NCT02485145 | Osteoarthritis of the Hands | Early Phase 1 | Unknown | March 2016 | - |
| NCT02107352 | - | - | Completed | - | Belgium ... more >> CHU Brugmann Brussels, Belgium, 1020 Collapse << |
| NCT01013480 | Fragile X Syndrome | Phase 2 | Terminated(all active subjects... more >> rolled into 209FX303/NCT01013480) Collapse << | - | United States, California ... more >> University of California-Los Angeles Neuropsychiatric Institute Los Angeles, California, United States, 90024 M.I.N.D. Institute Sacramento, California, United States, 95817 United States, Illinois Rush University Medical Center Chicago, Illinois, United States, 60612 United States, New York NYS Institute for Basic Research in Developmental Disabilities Staten Island, New York, United States, 10314 United States, North Carolina University of North Carolina Neurosciences Hospital Chapel Hill, North Carolina, United States, 27514 United States, Pennsylvania Suburban Research Associates Media, Pennsylvania, United States, 19063 United States, Tennessee Vanderbilt Kennedy Center Nashville, Tennessee, United States, 37203 United States, Texas Red Oaks Psychiatry Associates, PA Houston, Texas, United States, 77090 United States, Washington Seattle Children's Hospital Seattle, Washington, United States, 98101 Collapse << |
| NCT03594552 | Autism Spectrum Disorder | Not Applicable | Recruiting | February 2, 2020 | United Kingdom ... more >> King's College London Recruiting London, United Kingdom, SE5 8AF Contact: Gráinne McAlonan, PhD 02078480831 grainne.mcalonan@kcl.ac.uk Collapse << |
| NCT03199417 | Knee Osteoarthritis | Phase 2 Phase 3 | Recruiting | December 1, 2019 | Canada, Ontario ... more >> Oakville Trafalgar Memorial Hospital Recruiting Oakville, Ontario, Canada, L6M 0L8 Contact: Moin Khan, MD 7346607601 moinkhanmd@gmail.com Collapse << |
| NCT02361242 | Alzheimer Disease | Phase 2 | Completed | - | France ... more >> CMRR Bordeaux, France Collapse << |
| NCT01064973 | Autism Spectrum Disorders | Phase 2 | Terminated(all active subjects... more >> were rolled into study 209AS209/NCT01706523) Collapse << | - | United States, Arizona ... more >> Southwest Autism Research & Resource Center Phoenix, Arizona, United States, 85006 United States, California University of California-Los Angeles Neuropsychiatric Institute Los Angeles, California, United States, 90024 United States, Connecticut Yale Child Study Center New Haven, Connecticut, United States, 06520 United States, Indiana Riley Hospital for Children Indianapolis, Indiana, United States, 46202 United States, North Carolina University of North Carolina Neurosciences Hospital Chapel Hill, North Carolina, United States, 27514 United States, Tennessee Vanderbilt Kennedy Center Nashville, Tennessee, United States, 37203 United States, Texas Red Oaks Psychiatry Associates, P.A. Houston, Texas, United States, 77090 United States, Washington Seattle Children's Hospital Seattle, Washington, United States, 98101 Collapse << |
| NCT00004793 | - | - | Completed | - | - |
| NCT02361424 | Alzheimer Disease | Phase 2 | Completed | - | France ... more >> CMRR Bordeaux, France Collapse << |
| NCT00179114 | Spasticity | Phase 4 | Completed | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Collapse << |
| NCT00164801 | Non-Cardiac Chest Pain | Not Applicable | Terminated(Funding ended) | - | China ... more >> Endoscopy Centre, Prince of Wales Hospital Hong Kong, China Collapse << |
| NCT00488839 | Multiple Sclerosis | Phase 3 | Completed | - | - |
| NCT00218166 | Cocaine-Related Disorders | Phase 2 | Completed | - | United States, Kentucky ... more >> University of Kentucky Medical Center Lexington, Kentucky, United States, 40536 0086 Collapse << |
| NCT00414856 | Gastroesophageal Reflux Diseas... more >>e Collapse << | Phase 1 | Completed | - | Belgium ... more >> Novartis Investigative site Brussels, Belgium France Novartis Investigative site Paris, France Germany Novartis Investigative Site Nuernberg, Germany Switzerland Novartis Investigative site Bern, Switzerland Collapse << |
| NCT00255073 | Spastic Diplegic Cerebral Pals... more >>y Collapse << | Phase 2 | Completed | - | United States, California ... more >> Stanford University Stanford, California, United States, 94305-5235 Collapse << |
| NCT00461604 | - | - | Completed | - | Germany ... more >> Technical University of Munich Munich, Bavaria, Germany, 81675 Collapse << |
| NCT01265550 | GERD | Phase 3 | Completed | - | United States, Alabama ... more >> Birmingham VA Medical Center, Birmingham, AL Birmingham, Alabama, United States, 35233 United States, Arizona Southern Arizona VA Health Care System, Tucson, AZ Tucson, Arizona, United States, 85723 United States, California VA Loma Linda Healthcare System, Loma Linda, CA Loma Linda, California, United States, 92357 VA Long Beach Healthcare System, Long Beach, CA Long Beach, California, United States, 90822 United States, Connecticut VA Connecticut Healthcare System West Haven Campus, West Haven, CT West Haven, Connecticut, United States, 06516 United States, Maryland Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD Baltimore, Maryland, United States, 21201 United States, Massachusetts VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA Boston, Massachusetts, United States, 02130 United States, Michigan VA Ann Arbor Healthcare System, Ann Arbor, MI Ann Arbor, Michigan, United States, 48105 United States, Missouri Kansas City VA Medical Center, Kansas City, MO Kansas City, Missouri, United States, 64128 United States, New York Syracuse VA Medical Center, Syracuse, NY Syracuse, New York, United States, 13210 United States, North Carolina Durham VA Medical Center, Durham, NC Durham, North Carolina, United States, 27705 Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC Salisbury, North Carolina, United States, 28144 United States, Texas VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX Dallas, Texas, United States, 75216 Michael E. DeBakey VA Medical Center, Houston, TX Houston, Texas, United States, 77030 United States, Washington VA Puget Sound Health Care System Seattle Division, Seattle, WA Seattle, Washington, United States, 98108 Collapse << |
| NCT03058237 | Healthy Volunteers | Phase 1 | Completed | - | United Kingdom ... more >> Quotient Clinical Ruddington, Nottingham, United Kingdom, NG11 6JS Collapse << |
| NCT01265550 | - | - | Completed | - | - |
| NCT00914290 | Spasticity Mu... more >>ltiple Sclerosis Collapse << | Phase 2 | Completed | - | United States, Arizona ... more >> Northwest NeuroSpecialists, PLLC Tucson, Arizona, United States, 85741 United States, Colorado University of Colorado Aurora, Colorado, United States, 80045 United States, Florida Meridien Research Tampa, Florida, United States, 33606 United States, Indiana Fort Wayne Neurological Center Fort Wayne, Indiana, United States, 46805 United States, Kansas MidAmerica Neuroscience Institute Lenexa, Kansas, United States, 66214 United States, Michigan QUEST Research Institute Bingham Farms, Michigan, United States, 48025 United States, Montana Great Falls Cllinic Great Falls, Montana, United States, 59405 United States, New York Empire Neurology, PC Latham, New York, United States, 12110 Winthrop University Hospital Mineola, New York, United States, 11501 United States, North Carolina Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 United States, Texas Central Texas Neurology Consultants Round Rock, Texas, United States, 78681 Collapse << |
| NCT01712087 | - | - | Terminated(Lack of enrollment) | July 2020 | United States, Massachusetts ... more >> UMass Memorial Medical Center Worcester, Massachusetts, United States, 01655 United States, Texas Methodist Hospital Research Institute Houston, Texas, United States, 77030 Collapse << |
| NCT00139789 | Multiple Sclerosis | Phase 3 | Completed | - | United States, Wisconsin ... more >> Schwarz Milwaukee, Wisconsin, United States Collapse << |
| NCT01053585 | Gastroesophageal Reflux Diseas... more >>e Collapse << | Not Applicable | Completed | - | Switzerland ... more >> Division of Gastroenterology Zurich, Switzerland, CH-8091 Collapse << |
| NCT00640003 | Ataxia Telangiectasia | Early Phase 1 | Completed | - | United States, Maryland ... more >> Johns Hopkins Hospital Baltimore, Maryland, United States, 21108 Johns Hopkins Hospital Baltimore, Maryland, United States, 21287 Collapse << |
| NCT01743651 | Spasticity Mu... more >>ltiple Sclerosis Collapse << | Phase 3 | Completed | - | - |
| NCT01563224 | No Condition ... more >>Brain GABA-B Function Collapse << | Not Applicable | Completed | - | United Kingdom ... more >> Neuropsychopharmacology, Imperial College London, United Kingdom, W12 0NN Collapse << |
| NCT00004431 | Trigeminal Neuralgia | Not Applicable | Completed | - | United States, Pennsylvania ... more >> University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania, United States, 15261 Collapse << |
| NCT00367068 | Cerebral Palsy ... more >> Spasticity Collapse << | Phase 3 | Completed | - | Netherlands ... more >> University Hospital Maastricht Maastricht, Netherlands, NL 6202 AZ Collapse << |
| NCT02001584 | Healthy Volunteers; ... more >> Obese, Otherwise Healthy Volunteers Collapse << | Phase 1 | Completed | - | United Kingdom ... more >> Quintiles Drug Research Unit at Guy's Hospital London, United Kingdom Collapse << |
| NCT01955655 | Recurrent Crying Spells | Phase 4 | Completed | - | India ... more >> Sathbhavana Brain Clinic Secunderabad, Andhra Pradesh, India, 500025 Collapse << |
| NCT01032239 | Severe Spasticity | Phase 4 | Completed | - | - |
| NCT03068897 | Low Back Pain | Phase 4 | Completed | - | United States, New York ... more >> Montefiore Medical Center Bronx, New York, United States, 10467 Collapse << |
| NCT00082485 | Cocaine-Related Disorders | Phase 2 | Completed | - | United States, California ... more >> San Francisco General Hosptial San Francisco, California, United States, 94110 Torrance Site Torrance, California, United States, 90502 United States, Colorado Denver VA Medical Center Denver, Colorado, United States, 80220 United States, Maryland VA Maryland Healthcare System Baltimore, Maryland, United States, 21201 United States, Pennsylvania U of Penn School of Medicine Philadelphia, Pennsylvania, United States, 19104 6178 United States, Texas South TX VA Health Care System San Antonio, Texas, United States, 78284 4404 United States, Utah Salt Lake City VA Medical Center Salt Lake City, Utah, United States, 84148 United States, Virginia Institute of Resch & Educ Inova Fairfax Hospital Falls Church, Virginia, United States, 22042 3300 Collapse << |
| NCT01032239 | - | - | Completed | - | - |
| NCT03151941 | - | - | Completed | - | United Kingdom ... more >> Solent NHS Trust Portsmouth, Hampshire, United Kingdom Collapse << |
| NCT00000303 | Cocaine-Related Disorders | Phase 2 | Completed | - | United States, California ... more >> Friends Research Institute Los Angeles, California, United States, 90025 Collapse << |
| NCT00802035 | Alcohol Dependence | Phase 1 | Completed | - | United States, Texas ... more >> CEDRA Clinical Research, LLC Austin, Texas, United States, 78759 Collapse << |
| NCT03427216 | Pelvic Floor Dyssynergia | Not Applicable | Not yet recruiting | December 31, 2018 | - |
| NCT00493428 | Hepatocellular Carcinoma | Phase 2 | Withdrawn(The study have been ... more >>stoped because the protocol is going to be modify.) Collapse << | - | Canada, Manitoba ... more >> Liver Unit, Section of Hepatology, Department of Medicine,Health Sciences Centre Winnipeg, Manitoba, Canada, R3E 3P4 Liver Unit, health sciences Centre Winnipeg, Manitoba, Canada Collapse << |
| NCT00221611 | Cerebral Palsy | Phase 2 | Completed | - | Belgium ... more >> University Hospital Ghent Ghent, Belgium, 9000 Collapse << |
| NCT00647738 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Algorithme Pharma Montreal, Quebec, Canada, H4N 2Y8 Collapse << |
| NCT00752934 | Cerebral Palsy | Phase 4 | Unknown | September 2012 | Israel ... more >> Saare Zedek Medical Center Recruiting Jerusalem, Israel Contact: Hilla Ben Pazi, MD Benpazi@gmail.com Collapse << |
| NCT01051128 | Spasticity | Phase 3 | Withdrawn(Study was never star... more >>ted. Full IDE-approval not obtained. new IDE will be submitted) Collapse << | December 2010 | - |
| NCT01711125 | Alcoholic Liver Disease ... more >> Alcohol Dependence Collapse << | Phase 3 | Completed | - | Australia, New South Wales ... more >> Drug Health Services, Royal Prince Alfred Hospital Sydney, New South Wales, Australia, 2050 Collapse << |
| NCT02462317 | Muscle Spasticity | Phase 4 | Recruiting | September 2020 | France ... more >> University Hospital, Toulouse Recruiting Toulouse, Haute-Garonne, France, 31059 Contact: Philippe MARQUE, MD PHD 5 61 32 28 01 ext 33 marque.ph@chu-toulouse.fr Principal Investigator: Philippe MARQUE, MD PHD CHU Jean Minjoz Not yet recruiting Besançon, France, 25030 Contact: Bernard PARRATTE, MD PHD 3 63 08 25 51 ext 33 bernard.parratte@univfcomte.fr Groupe Pellegrin, University Hospital Bordeaux Not yet recruiting Bordeaux, France, 33076 Contact: Patrick DEHAIL, PHD MD 556796006 ext 33 patrick.dehail@chubordeaux.fr Centre de rééducation MARIENIA Not yet recruiting Cambo Les Bains, France, 64250 Contact: Michel BEGUE, MD 559936801 ext 33 m.begue@marienia.fr Centre Bouffard- Vercelli Not yet recruiting Cerbere, France, 66290 Contact: Michel ENJALBERT, MD 4 68 88 75 00 ext 33 michel.enjalbert@wanadoo.fr University Hospital Dijon Not yet recruiting Dijon, France, 21079 Contact: Charles BENAIM, MD PHD 380293643 ext 33 charles.benaim@chu-dijon.fr University Hospital Grenoble Not yet recruiting Echirolles, France, 38434 Contact: Dominic PERENNOU, MD PHD 4 76 76 60 83 ext 33 DPerennou@chu-grenoble.fr Hôpital R. Poincarré Not yet recruiting Garches, France, 92380 Contact: Alexis SCHNITZER, MD 1 47 10 77 26 ext 33 alexis.schnitzler@rpc.aphp.fr Hôpital Swynghedauw Not yet recruiting Lille, France, 59000 Contact: Etienne ALLART, MD 3-20-44-58-32 ext 33 Etienne.ALLART@CHRU-LILLE.FR Hôpital J Rebeyrol Not yet recruiting Limoges, France, 87042 Contact: Jean- Christophe DAVIET, MD PHD 5 55 05 65 13 ext 33 jean-Christophe.Daviet@chu-limoges.fr CHU Gui de Chauliac Not yet recruiting Montpellier, France, 34295 Contact: Isabelle LAFFOND, MD 4 67 33 87 17 ext 33 i-laffont@chu-montpellier.fr University Hospital Carémeau Not yet recruiting Nimes, France, 30029 Contact: Frédéric PELLAS, MD PHD 4 66 68 34 59 ext 33 frederic.pellas@chu-nimes.fr Hopital Rothschild Not yet recruiting Paris, France, 75012 Contact: Gilberte ROBAIN, MD PHD 1 49 59 46 97 ext 33 gilberte.robain@rth.aphp.fr GH Lariboisière F.Widal Not yet recruiting Paris, France, 75013 Contact: Alain YELNIK, MD PHD 1 40 05 48 51 ext 33 alain.yelnik@lrb.aphp.fr Groupe Hospitalier Pitié-Salpêtrière Not yet recruiting Paris, France, 75013 Contact: Dominique MAZEVET, MD 1 42 16 11 48 ext 33 dominique.mazevet@psl.aphp.fr Université Reims Champagne Ardenne Not yet recruiting Reims, France, 51092 Contact: François BOYER, MD PHD 3 26 78 44 80 ext 33 fboyer@chu-reims.fr Pôle MPR St Hélier Not yet recruiting Rennes, France, 35000 Contact: Philippe GALLIEN, MD 2 99 29 50 80 ext 33 philippe.gallien@polesthelier.com Collapse << |
| NCT00221689 | Traumatic Brain Injury ... more >> Cerebral Anoxia Coma Hypertonia Dysautonomia Collapse << | Phase 2 | Terminated(very slow recruitme... more >>nt and treatments beyond expiry date) Collapse << | - | France ... more >> Service de neurochirurgie B, Hôpital Pellergin Tripode Bordeaux, France, 33076 Collapse << |
| NCT00516503 | Chronic Myeloproliferative Dis... more >>orders Leukemia Lymphoma Lymphoproliferative Disorder Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms Neurotoxicity Pain Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 3 | Completed | - | - |
| NCT00516503 | - | - | Completed | - | - |
| NCT00525252 | Liver Cirrhosis, Alcoholic | Phase 1 Phase 2 | Completed | - | - |
| NCT00373295 | Marijuana Dependence | Phase 2 | Completed | - | United States, New York ... more >> New York State Psychiatric Institute New York, New York, United States, 10032 Collapse << |
| NCT00257894 | Nicotine Use Disorder ... more >> Nicotine Dependence Smoking Tobacco Use Disorder Collapse << | Phase 2 | Terminated(Enrollment was comp... more >>leted with insufficient sample size for publishable results) Collapse << | - | United States, Rhode Island ... more >> VA Medical Center, Providence Providence, Rhode Island, United States, 02908 Collapse << |
| NCT03034408 | Alcohol Use Disorder | Phase 2 | Recruiting | December 2018 | Switzerland ... more >> Service d'Addictologie, Hôpitaux Universitaires de Genève Recruiting Geneva, Switzerland, 1202 Contact: Zullino F Daniele, MD +41223725750 daniele.zullino@hcuge.ch Collapse << |
| NCT00373295 | - | - | Completed | - | - |
| NCT02011516 | - | - | Completed | - | - |
| NCT03065998 | Drug Abuse | Early Phase 1 | Recruiting | January 2019 | Israel ... more >> Retorno rehabilitation center Recruiting Bet Shemesh, Israel Contact: Eitan Eckstein 9-73-210439 eitan@retorno.org Contact: Shira Eckstein 972-2-5318123 shiraeckbiu@gmail.com Collapse << |
| NCT00320047 | Eating Disorders ... more >> Bulimia Nervosa Collapse << | Not Applicable | Completed | - | United States, New York ... more >> Eating Disorders Clinic, New York State Psychiatric Institute New York, New York, United States, 10032 Collapse << |
| NCT00280280 | Spasticity | Phase 1 | Terminated(low patient accrual... more >>) Collapse << | - | United States, Tennessee ... more >> Vanderbilt University Nashville, Tennessee, United States, 37232-2551 Collapse << |
| NCT01266655 | Alcohol Dependence | Phase 2 Phase 3 | Completed | - | Germany ... more >> Department of Psychiatry, Charité Campus Mitte, Charité - Universitätsmedizin Berlin Berlin, Germany, 10117 Collapse << |
| NCT00257894 | - | - | Terminated(Enrollment was comp... more >>leted with insufficient sample size for publishable results) Collapse << | - | - |
| NCT02011516 | Marijuana Dependence | Phase 2 | Completed | - | United States, Pennsylvania ... more >> University of Pennsylvania Center for Studies of Addiction Philadelphia, Pennsylvania, United States, 19104 Collapse << |
| NCT01751386 | Alcoholism Al... more >>cohol Dependence Alcohol Drinking Related Problems Alcohol Drinking Anxiety Disorder Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00614328 | Alcohol Dependence | Phase 1 | Completed | - | - |
| NCT01751386 | - | - | Completed | - | - |
| NCT01008280 | Hepatitis C A... more >>lcohol Use Disorders Collapse << | Phase 4 | Completed | - | United States, California ... more >> VA Long Beach Healthcare System, Long Beach, CA Long Beach, California, United States, 90822 VA San Diego Healthcare System, San Diego, CA San Diego, California, United States, 92161 United States, Minnesota VA Medical Center, Minneapolis Minneapolis, Minnesota, United States, 55417 United States, Oregon VA Medical Center, Portland Portland, Oregon, United States, 97201 Collapse << |
| NCT01172509 | Autism | Phase 1 | Terminated(too much variabilit... more >>y in the TMS measures) Collapse << | - | United States, Massachusetts ... more >> Berenson-Allen Center for Noninvansive Brain Stimulation Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 Collapse << |
| NCT01008280 | - | - | Completed | - | - |
| NCT03720717 | Pain | Phase 4 | Not yet recruiting | February 1, 2020 | - |
| NCT01095679 | CHEYNE Stokes Respiration | Phase 1 | Completed | - | France ... more >> Pitié-Salpêtrière Hospital Paris, France, 75013 Collapse << |
| NCT02705950 | Neuropathic Pain | Not Applicable | Unknown | March 2016 | Spain ... more >> Institut Guttmann Recruiting Badalona, Barcelona, Spain, 08916 Collapse << |
| NCT01003249 | Overactive Bladder ... more >> Constipation Lower Urinary Tract Symptoms Collapse << | Phase 4 | Terminated(recruitment was goi... more >>ng too slowly) Collapse << | - | United States, North Carolina ... more >> Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 Collapse << |
| NCT02298868 | Muscle Cramps ... more >> Cirrhosis Collapse << | Phase 2 | Completed | - | - |
| NCT02298868 | - | - | Completed | - | - |
| NCT02529514 | Sleep | Phase 4 | Suspended | June 2016 | Belgium ... more >> Centre Hospitalier Universitaire de Liège Liège, Belgium, 4000 Collapse << |
| NCT02723383 | Alcoholism | Phase 3 | Recruiting | March 27, 2020 | France ... more >> CHU ANGERS - réanimation chirurgicale Recruiting Angers, France Principal Investigator: Sigismond LASOCKI CHU de Brest Réanimation Chirurgicale Recruiting Brest, France Contact: Olivier HUET, MD olivier.huet@chu-brest.fr Principal Investigator: Olivier HUET CHU de Brest Réanimation Médicale Recruiting Brest, France Contact: Erwan L'HER, MD erwan.lher@chu-brest.fr Principal Investigator: Erwan L'HER, MD CHU de Caen Réanimation Médicale Not yet recruiting Caen, France Contact: Damien Du Cheyron, MD ducheyron-d@chu-caen.fr Principal Investigator: Damien Du Cheyron, MD CHD La Roche Sur YON Recruiting La Roche Sur Yon, France Principal Investigator: Jean-Claude Lacherade CH Le Mans Not yet recruiting Le Mans, France Contact: Christophe GUITTON, MD Principal Investigator: Christophe GUITTON Centre Hospitalier de Bretagne Sud Réanimation Polyvalente Lorient Not yet recruiting Lorient, France Contact: Roland SMONIG, MD r.smonig@ghbs.bzh Principal Investigator: Roland SMONIG, MD CHU MONTPELLIER - Lapeyronie Recruiting Montpellier, France Principal Investigator: Boris JUNG Chu Montpellier Recruiting Montpellier, France Principal Investigator: Samir JABER CHU NANTES - réanimation chirurgicale Recruiting Nantes, France Principal Investigator: Pierre Joachim MAHE CHU NANTES -réanimation médicale Recruiting Nantes, France Principal Investigator: NOELLE BRULE Hopital Saint Antoine Recruiting Paris, France Principal Investigator: Thomas LESCOT Chu Poitiers Recruiting Poitiers, France Principal Investigator: Claire Dahyot-Fizelier Ch Cornouaille Recruiting Quimper, France Principal Investigator: Yann-Mickaël MORICONI Chu Rennes Recruiting Rennes, France Principal Investigator: Arnaud GACOUIN CHR Saint Nazaire Recruiting Saint Nazaire, France Principal Investigator: Maud JONAS CHRU Tours Bretonneau Recruiting Tours, France Contact: Stephan EHRMANN, MD stephan.ehrmann@univ-tours.fr Principal Investigator: Stephan EHRMANN, MD Chu Tours Recruiting Tours, France Principal Investigator: Martine FERRANDIERE Collapse << |
| NCT00877734 | Alcohol Dependence | Phase 2 Phase 3 | Completed | - | United States, North Carolina ... more >> University of North Carolina at Chapel Hill School of Medicine Chapel Hill, North Carolina, United States, 27599-7160 Collapse << |
| NCT01002105 | Alcohol Dependence | Phase 4 | Completed | - | Israel ... more >> Alexander Grinshpoon Hadera, Israel, Mobil Post Hefer 37806 Collapse << |
| NCT00597701 | - | - | Completed | - | - |
| NCT01003249 | - | - | Terminated(recruitment was goi... more >>ng too slowly) Collapse << | - | - |
| NCT00597701 | Alcohol Withdrawal Delirium | Not Applicable | Completed | - | United States, Minnesota ... more >> Essentia Health Duluth, Minnesota, United States, 55805 Collapse << |
| NCT01002105 | - | - | Completed | - | - |
| NCT01076283 | Alcoholism | Phase 2 | Completed | - | United States, Rhode Island ... more >> Brown University Center for Alcohol and Addiction Studies Providence, Rhode Island, United States, 02903 Collapse << |
| NCT01352611 | Autism Spectrum Disorder | Not Applicable | Withdrawn(No subjects enrolled... more >>.) Collapse << | - | United States, Missouri ... more >> University Hospital/University of Missouri Health Care Columbia, Missouri, United States, 65212 Collapse << |
| NCT00607542 | Spasticity Ce... more >>rebral Palsy Collapse << | Phase 1 Phase 2 | Completed | - | United States, Illinois ... more >> Rehabilitation Institute of Chicago Chicago, Illinois, United States, 60611 United States, Louisiana Children's Hospital of Lousiana New Orleans, Louisiana, United States, 70118 United States, Maryland Kennedy Krieger Institute Baltimore, Maryland, United States, 21205 United States, Minnesota Gillette Children's Speciality Healthcare St. Paul, Minnesota, United States, 55101 United States, Missouri Children's Mercy Hospital and Clinics Kansas City, Missouri, United States, 64108 Washington Univeristy - St. Louis Children's hospital St. Louis, Missouri, United States, 63110-1093 United States, New York SUNY Upstate Medical University Syracuse, New York, United States, 13210 United States, Ohio Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229-3039 United States, Texas Texas Children's Hospital Houston, Texas, United States, 77030 United States, Virginia Kluge Children's Rehabilitation Center - University of Virginia Charlottesville, Virginia, United States, 22903 United States, Washington Seattle Children's Hospital Seattle, Washington, United States, 98105 Collapse << |
| NCT02835365 | - | - | Active, not recruiting | January 2020 | France ... more >> Centre hospitalier yves LEFOLL Saint Brieux, Côtes d'Armor, France, 22023 Centre Hospitalier Régional Universitaire Hôpital Jean Minjoz Besançon, Franche-Comté, France, 25030 CH Béziers Béziers, Hérault, France, 34525 Hôpital saint denis Saint denis, Ile de France, France, 93205 CH Orleans Orleans, Loiret, France, 45067 GHPSO Creil-Senlis Creil, Oise, France, 60109 CH meaux Meaux, Seine et marne, France, 77100 CHI CRETEIL addictology Creteil, France, 94000 Collapse << |
| NCT01604330 | Alcoholism | Phase 2 Phase 3 | Completed | - | France ... more >> Paris Descartes University Paris, France, 75014 Collapse << |
| NCT01980706 | Alcoholism | Phase 2 | Completed | - | United States, North Carolina ... more >> University of North Carolina at Chapel Hill Chapel Hill, North Carolina, United States, 27599 Collapse << |
| NCT00871455 | Spinal Cord Injury | Not Applicable | Completed | - | United States, New York ... more >> VA Medical Center, Bronx Bronx, New York, United States, 10468 Collapse << |
| NCT02003664 | Cocaine Dependence | Phase 2 | Withdrawn(This study never sta... more >>rted due to delays in medication development) Collapse << | November 2014 | United States, Pennsylvania ... more >> Center for the Studies of Addiction Philadelphia, Pennsylvania, United States, 19104 Collapse << |
| NCT03293017 | Alcohol Use Disorder ... more >> Alcohol Withdrawal Collapse << | Phase 4 | Recruiting | February 1, 2020 | Belgium ... more >> University Hospital Brussels Recruiting Brussels, Belgium, 1090 Contact: Cleo L Crunelle, PhD nacstudie@gmail.com Collapse << |
| NCT01738282 | Alcohol Dependence | Phase 3 | Completed | - | France ... more >> Angers, France Bron, France Clermont de l'Oise, France CHU Clermont Ferrand, France Hopital Beaujon Clichy, France Dax, France Centre hospitalier Dijon, France Centre hospitalier Erstein, France L'Arbresle, France Centre hospitalier La Membrolle sur Choisille, France Hopital Michallon La Tronche, France Centre hospitalier Le Mans, France CHRU Lille, France CSAPA Lille, France Limoges, France Hopital de la Croix Rousse Lyon, France Hopital Sainte Marguerite Marseille, France Centre hospitalier Montauban, France Morlaix, France Hopital Villemin Nancy, France CHU Nantes, France Centre hospitalier Nice, France CHRU Nimes, France Hopital Bichat Claude Bernard Paris, France Hopital Cochin Paris, France Hopital Fernand Widal Paris, France Hopital Saint Anne Paris, France Centre hospitalier Perpignan, France Centre hospitalier Pont du Casse, France Reims, France Hopital Pontchaillou Rennes, France Hopital de la Fraternité Roubaix, France Saint Egreve, France Hopital René Muret Sevran, France CSAPA Seynod, France Centre hospitalier intercommunal Toulon, France Hopital Brabois Vandoeuvre les Nancy, France Hopital Paul Brousse Villejuif, France Collapse << |
| NCT01386255 | Cerebral Palsy ... more >> GERD Collapse << | Phase 4 | Withdrawn(No participants were... more >> enrolled) Collapse << | - | United States, Massachusetts ... more >> Children's Hospital Boston Boston, Massachusetts, United States, 02115 Collapse << |
| NCT01821560 | Nicotine Dependence | Phase 2 | Completed | - | United States, Pennsylvania ... more >> University of Pennsylvania Center for Studies of Addiction Philadelphia, Pennsylvania, United States, 19104 Collapse << |
| NCT02052440 | Alcohol Withdrawal Syndrome | Phase 3 | Terminated(Insufficient fundin... more >>g to complete with low enrollment rate) Collapse << | - | United States, Colorado ... more >> Denver Health Hospital Denver, Colorado, United States, 80204 Collapse << |
| NCT01076283 | - | - | Completed | - | - |
| NCT01937364 | - | - | Terminated(The enrollment in t... more >>he study was too limited for meaningful data analysis.) Collapse << | - | - |
| NCT01228994 | Nicotine Dependence | Phase 2 | Terminated(The study was termi... more >>nated because of difficulties recruiting subjects.) Collapse << | - | Canada, Ontario ... more >> Centre for Addiction and Mental Health- 33 Russell St Toronto, Ontario, Canada, M5S2S1 Collapse << |
| NCT02052440 | - | - | Terminated(Insufficient fundin... more >>g to complete with low enrollment rate) Collapse << | - | - |
| NCT02221570 | Muscle Cramps ... more >> Liver Cirrhosis Collapse << | Not Applicable | Unknown | November 2014 | Egypt ... more >> Tanta University Hospital Recruiting Tanta, Gharbia, Egypt Contact: Asem A Elfert, MD +20-122-437-8188 asem1967@yahoo.com Principal Investigator: Asem A Elfert, MD Collapse << |
| NCT01931319 | Safety and Pharmacokinetics of... more >> Intravenous Baclofen Collapse << | Phase 1 | Completed | - | United States, Minnesota ... more >> University of Minnesota Minneapolis, Minnesota, United States, 55455 Collapse << |
| NCT03113396 | Rumination Su... more >>pra-gastric Belching Collapse << | Phase 4 | Completed | - | - |
| NCT01520545 | Severe Spasticity | Phase 3 | Completed | - | United States, Arkansas ... more >> Arkansas Children's Hospital Little Rock, Arkansas, United States, 72202 United States, California Loma Linda University Loma Linda, California, United States, 92354 United States, Florida Rehabilitation Medicine Department, University of Miami, Miller School of Medicine Miami, Florida, United States, 33136 United States, Illinois Rehabilitation Institute of Chicago Chicago, Illinois, United States, 60611 United States, Michigan Wayne State University, School of Medicine Dearborn, Michigan, United States, 48124 United States, Minnesota Gillette Children's Specialty Healthcare Saint Paul, Minnesota, United States, 55101 United States, Ohio Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 The Ohio State University Columbus, Ohio, United States, 43221 United States, Tennessee Vanderbilt University Medical Center, Department of Pediatrics Nashville, Tennessee, United States, 37232 United States, Texas Cook Children's Health Care System Fort Worth, Texas, United States, 76104 TIRR Memorial Hermann Houston, Texas, United States, 77030 United States, Utah University of Utah, Division of PM&R Salt Lake City, Utah, United States, 84132 United States, Wisconsin The Medical College of Wisconsin Department of Physical Medicine and Rehabilitation Milwaukee, Wisconsin, United States, 53226 Collapse << |
| NCT01937364 | Alcoholism Al... more >>cohol Withdrawal Collapse << | Phase 2 | Terminated(The enrollment in t... more >>he study was too limited for meaningful data analysis.) Collapse << | - | United States, Minnesota ... more >> St. Mary's Medical Center Duluth, Minnesota, United States, 55805 United States, North Dakota Essentia Health Innovis Hospital Fargo, North Dakota, United States, 58103 Collapse << |
| NCT02903823 | Muscle Spasticity | Phase 4 | Recruiting | December 2019 | United States, Tennessee ... more >> Vanderbilt University Recruiting Nashville, Tennessee, United States, 37232 Contact: Peter E Konrad, MD, Ph.D. 615-343-9822 peter.konrad@vanderbilt.edu Contact: Melba T Isom 615-343-9822 melba.isom@vanderbilt.edu Principal Investigator: Peter E Konrad, MD, Ph.D. Collapse << |
| NCT01749319 | Baclofen Withdrawal Syndrome | Phase 1 | Completed | - | United States, Minnesota ... more >> University of Minnesota Minneapolis, Minnesota, United States, 55455 Collapse << |
| NCT02760992 | Intravenous Baclofen | Phase 1 Phase 2 | Unknown | December 2017 | - |
| NCT02596763 | Alcohol Use Disorder | Phase 4 | Recruiting | January 2019 | France ... more >> Hospital Center Recruiting Abbeville, France, 80100 Contact: Maroussia WILQUIN, MD Centres de Soins, d'Accompagnement et de Prévention en Addictologie (CSAPA) Le Cèdre Bleu Recruiting Armentières, France, 59280 Contact: Marie-Christine BLANQUARD, MD Hospital Center Recruiting Arras, France, 62000 Contact: Dominique LEJEUNE, MD Service d'Aide aux Toxicomanes (SATO-Picardie) Recruiting Beauvais, France, 60000 Contact: Jean-Jacques PIK, MD Hospital Center Recruiting Boulogne, France, 62200 Contact: Frédéric TEISSIERE, MD University Hospital of Caen Not yet recruiting Caen, France Contact: François VABRET, MD, PhD Contact: Nicolas CABE, MD Hospital Center Recruiting Carvin, France, 62220 Contact: Hugo FAVRE, MD Hospital Center Recruiting Clermont, France, 60600 Contact: Sophie VELASTEGUI, MD Hospital Center Recruiting Dunkerque, France, 59300 Contact: Cécile RICHEZ, MD Hospital Center Recruiting Ham, France, 80400 Contact: Michel SOCHALA, MD Hospital Center Recruiting Hazebrouck, France, 59190 Contact: Lucie MOLMY, MD Hospital Center Recruiting Lens, France, 62300 Contact: Christelle DUBOCAGE, MD Etablissement Public de Santé Mentale (EPSM) Recruiting Lille, France, 59000 Contact: Véronique VOSGIEN, MD Hospital Center Recruiting Roubaix, France, 59100 Contact: Laurent URSO, MD University Hospital of Rouen Not yet recruiting Rouen, France Contact: Alexandre BAGUET, MD Hospital Center Recruiting Saint Pol sur Ternoise, France, 62130 Contact: Dominique LEJEUNE, MD Hospital Center Recruiting Saint-Amand-les-Eaux, France, 59230 Contact: Charles LESCUT, MD Hospital Center Recruiting Tourcoing, France, 59200 Contact: Laure SPINOSI, MD Hospital Center Recruiting Valenciennes, France, 59300 Contact: Alexandre BONORD, MD Collapse << |
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