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CAS No.: 122-11-2

磺胺地索辛 Catalog No. CSN12002

Synonyms: Sulphadimethoxine;NSC 683544;Madriqid

Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections and most frequently used in veterinary medicine.

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纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Sulfadimethoxine (SDM) is an antibiotic often used in combination with ormetoprim to prevent the spread of disease in freshwater aquaculture^[1]. At antibiotic concentrations between 5 and 7 mg/L, SDM inhibited the growth of anammox bacteria and resulted in a decrease of Candidatus Brocadia abundance from 2.57% to 0.39%^[2]. The excess sulfadimethoxine (SDM) in the environment could lead to antibiotic resistance by microorganisms and may do harm to many aquatic organisms. H2PO4- improved the efficiency of SDM removal by KMnO4. Humic acid (0-10 mg L-1) promoted the removal of SDM, which was attributed to the generation of in situ MnO2^[3].
临床研究
NCT号适应症或疾病临床期招募状态预计完成时间地点
NCT00770250 - - Completed - -
NCT00695838 - - Completed - -
NCT00882128 - - Completed - -
更多
参考文献

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00770250	-	-	Completed	-	-
NCT00695838	-	-	Completed	-	-
NCT00882128	-	-	Completed	-	-

[1] Guerard JJ, Chin YP, Mash H, Hadad CM. Photochemical fate of sulfadimethoxine in aquaculture waters. Environ Sci Technol. 2009;43(22):8587–8592
[2] Du L, Cheng S, Hou Y, Sun X, Zhou D, Liu B. Influence of sulfadimethoxine (SDM) and sulfamethazine (SM) on anammox bioreactors: Performance evaluation and bacterial community characterization. Bioresour Technol. 2018;267:84–92
[3] Du L, Cheng S, Hou Y, Sun X, Zhou D, Liu B. Influence of sulfadimethoxine (SDM) and sulfamethazine (SM) on anammox bioreactors: Performance evaluation and bacterial community characterization. Bioresour Technol. 2018;267:84–92

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.2224 mL
- 16.1119 mL
- 32.2238 mL
- 5 mM
- 0.6445 mL
- 3.2224 mL
- 6.4448 mL
- 10 mM
- 0.3222 mL
- 1.6112 mL
- 3.2224 mL

技术信息

CAS号

122-11-2

储存条件

粉末: Keep in dark place,Inert atmosphere,Room temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C12H14N4O4S

运输

蓝冰

分子量

310.33

别名

Sulphadimethoxine;NSC 683544;Madriqid;Madroxin;磺胺二甲氧嗪;磺胺二甲氧嘧啶

溶解度

DMSO	65.0 mg/mL (209.5 mM)

动物实验配方

5% DMSO+30% PEG400+ 2% tween80 + 63% water

3 mg/mL

clear

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NCT00770250	-	-	Completed	-	-
NCT00695838	-	-	Completed	-	-
NCT00882128	-	-	Completed	-	-
NCT00909038	-	-	Completed	-	-
NCT01055353	-	-	Completed	-	-
NCT00909038	-	-	Completed	-	-
NCT03306537	-	-	Active, not recruiting	September 7, 2018	United Kingdom ... more >> Queen Alexandra Hospital Portsmouth, United Kingdom, PO6 3LY Collapse <<
NCT00833573	-	-	Completed	-	-

磺胺地索辛 Catalog No. CSN12002

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